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• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Pyridines and derivatives 2-halopyridines
• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Pyridines and derivatives Halopyridines 2-halopyridines

Introduction to 2-Bromo-3-methylpyridine (CAS No. 3430-17-9)

2-Bromo-3-methylpyridine, with the chemical formula C?H?BrN, is a significant intermediate in modern organic synthesis and pharmaceutical research. This compound, identified by its CAS number 3430-17-9, has garnered considerable attention due to its versatile applications in the development of bioactive molecules. Its unique structural features—comprising a brominated pyridine ring with a methyl substituent—make it a valuable building block for constructing more complex heterocyclic systems.

The< strong>2-bromo-3-methylpyridine molecule serves as a crucial precursor in the synthesis of various pharmacologically relevant compounds. Its bromine atom provides a reactive site for nucleophilic substitution reactions, enabling the introduction of diverse functional groups. This property is particularly useful in medicinal chemistry, where such intermediates are often employed to generate novel drug candidates targeting neurological disorders, infectious diseases, and cancer.

In recent years, 2-bromo-3-methylpyridine has been extensively studied for its role in the development of small-molecule inhibitors. For instance, researchers have leveraged this compound to synthesize kinase inhibitors, which are critical in oncology therapy. The pyridine core is a common motif in many approved drugs, and modifications at the 2- and 3-positions can significantly alter biological activity. A notable study published in *Journal of Medicinal Chemistry* highlighted the use of 2-bromo-3-methylpyridine to develop potent JAK2 inhibitors, which show promise in treating inflammatory diseases and certain leukemias.

Moreover, the< strong> CAS No. 3430-17-9 identifier ensures consistency and traceability in research and industrial applications. This standardized nomenclature is essential for regulatory compliance and collaboration across global scientific communities. The compound’s stability under standard storage conditions further enhances its utility as an industrial intermediate, allowing for efficient scaling up of synthetic pathways without degradation.

The< strong> 2-bromo-3-methylpyridine scaffold has also found utility in materials science, particularly in the design of organic electronic materials. Pyridine derivatives are known for their electron-withdrawing properties, which can influence charge transport in semiconductors and light-emitting diodes (LEDs). Recent advancements have demonstrated its incorporation into conjugated polymers used in flexible electronics, showcasing its broader applicability beyond traditional pharmaceuticals.

From a synthetic chemistry perspective, 2-bromo-3-methylpyridine offers a balance between reactivity and stability, making it an ideal candidate for multi-step syntheses. Its halogenated nature allows for cross-coupling reactions such as Suzuki-Miyaura and Buchwald-Hartwig couplings, which are pivotal in constructing biaryl structures found in many bioactive molecules. These reactions enable chemists to introduce aryl or heteroaryl groups with high selectivity and yield.

In conclusion, 2-Bromo-3-methylpyridine (CAS No. 3430-17-9) remains a cornerstone in synthetic organic chemistry and drug discovery. Its structural versatility and reactivity make it indispensable for researchers aiming to develop innovative therapeutic agents and advanced materials. As scientific understanding progresses, the utility of this compound is expected to expand further, solidifying its role as a fundamental building block in modern chemical research.

• 32864-29-2(2-Bromo-3-phenylpyridine)
• 117846-58-9(2,6-Dibromo-3,5-dimethylpyridine)
• 33204-85-2(2-bromo-3,4-dimethyl-pyridine)
• 3510-66-5(2-Bromo-5-methylpyridine)
• 101002-03-3(3,3'-Bipyridine, 2-bromo-)
• 35740-86-4(2-Bromo-3-methylquinoline)
• 887571-15-5(2,6-dibromo-3-methyl-pyridine)
• 205744-15-6((2-bromo-3-pyridyl)methanamine)
• 128071-93-2(2,4-Dibromo-3-methylpyridine)
• 92992-85-3(2-Bromo-3,5-dimethylpyridine)