Cas no 33889-68-8 ((R)-Fangchinoline)
(R)-Fangchinoline is a bioactive bisbenzylisoquinoline alkaloid derived from natural sources, notably the Stephania genus. It exhibits notable pharmacological properties, including anti-inflammatory, antitumor, and immunomodulatory activities. The compound's stereospecific (R)-configuration enhances its binding affinity to biological targets, contributing to its efficacy in modulating cellular pathways. (R)-Fangchinoline is widely utilized in research for studying signal transduction mechanisms, particularly in cancer and autoimmune disease models. Its high purity and well-characterized structure make it a reliable reference standard in analytical and pharmacological studies. The compound's stability and solubility profile further support its applicability in both in vitro and in vivo experimental settings.
(R)-Fangchinoline structure
Product Name:(R)-Fangchinoline
CAS No:33889-68-8
MF:C37H40N2O6
MW:608.7233
MDL:MFCD03427706
CID:54149
PubChem ID:321937
Update Time:2025-06-08
(R)-Fangchinoline Chemical and Physical Properties
Names and Identifiers
-
- Fangchinoline
- Menisidine
- (S,S)-(+)-tetrandine
- d,l-Fangchinolin
- Fangquinoline
- FF-0018
- I06-1344
- N1799
- THALRUGOSINE
- Limacine
- Demethyl tetrandrine
- Hanfangchin B
- Frangchinoline
- Cycleadrine
- NSC277171
- 7-O-Demethyltetrandine
- BCP26186
- 6,6',12-trimethoxy-2,2'-dimethylberbaman-7-ol
- 9,20,25-Trimethoxy-15,30-dimethyl-7,23-dioxa-15,30-diazaheptacyclo[22.6.2.23,6.18,12.114,18.027,31.0
- (R)-Fangchinoline
- MFCD03427706
- D78289
- AS-75329
- NSC-277171
- Thaligine
- SCHEMBL15042386
- (1S,14R)-9,20,25-trimethoxy-15,30-dimethyl-7,23-dioxa-15,30-diazaheptacyclo[22.6.2.23,6.18,12.114,18.027,31.022,33]hexatriaconta-3(36),4,6(35),8,10,12(34),18,20,22(33),24,26,31-dodecaen-21-ol
- Q-100478
- (+)-Thalrugosine
- 16H-1,24:6,9-DIETHENO-11,15-METHENO-2H-PYRIDO(2',3':17,18)(1,11)DIOXACYCLOEICOSINO(2,3,4-IJ)ISOQUINOLIN-22-OL, 3,4,4A,5,16A,17,18,19-OCTAHYDRO-12,21,26-TRIMETHOXY-4,17-DIMETHYL-, (4AS,16AR)-
- D-ISOFANGCHINOLINE
- Fangchinoline,(S)
- Thalrugosine;Thaligine
- s3606
- 863BR78K9R
- CCG-270221
- CHEMBL500614
- J17.831D
- 33889-68-8
- Berbaman-7-ol, 6,6',12-trimethoxy-2,2'-dimethyl-
- AKOS025402310
- AC-8013
- CS-0016779
- HY-N1372
- NSC 277171
- (1S,14R)-9,20,25-trimethoxy-15,30-dimethyl-7,23-dioxa-15,30-diazaheptacyclo[22.6.2.2(3),?.1?,(1)(2).1(1)?,(1)?.0(2)?,(3)(1).0(2)(2),(3)(3)]hexatriaconta-3,5,8(34),9,11,18(33),19,21,24(32),25,27(31),35-dodecaen-21-ol
- BDBM85443
- (11S,31R)-16,36,54-trimethoxy-12,32-dimethyl-11,12,13,14,31,32,33,34-octahydro-2,6-dioxa-1(7,1),3(8,1)-diisoquinolina-5(1,3),7(1,4)-dibenzenacyclooctaphan-37-ol
- THALRUGOSINE, (+)-
- Limacine (R,R)
- FT-0689329
- A924511
- B2703-465545
- (1S,14S)-9,20,25-trimethoxy-15,30-dimethyl-7,23-dioxa-15,30-diazaheptacyclo[22.6.2.2^{3,6.1^{8,12.1^{14,18.0^{27,31.0^{22,33]hexatriaconta-3(36),4,6(35),8,10,12(34),18,20,22(33),24,26,31-dodecaen-21-ol
- DTXSID90955479
- BS-42411
- AKOS015895878
- (1S,14R)-9,20,25-trimethoxy-15,30-dimethyl-7,23-dioxa-15,30-diazaheptacyclo[22.6.2.2^{3,6.1^{8,12.1^{14,18.0^{27,31.0^{22,33]hexatriaconta-3(36),4,6(35),8,10,12(34),18,20,22(33),24,26,31-dodecaen-21-ol
- Isofangchinoline
- SCHEMBL19236300
- FT-0686612
- DB-050260
- 436-77-1
- 9,20,25-TRIMETHOXY-15,30-DIMETHYL-7,23-DIOXA-15,30-DIAZAHEPTACYCLO[22.6.2.2(3),?.1?,(1)(2).1(1)?,(1)?.0(2)?,(3)(1).0(2)(2),(3)(3)]HEXATRIACONTA-3,5,8(34),9,11,18(33),19,21,24(32),25,27(31),35-DODECAEN-21-OL
-
- MDL: MFCD03427706
- Inchi: 1S/C37H40N2O6/c1-38-14-12-24-19-31(42-4)33-21-27(24)28(38)16-22-6-9-26(10-7-22)44-32-18-23(8-11-30(32)41-3)17-29-35-25(13-15-39(29)2)20-34(43-5)36(40)37(35)45-33/h6-11,18-21,28-29,40H,12-17H2,1-5H3
- InChI Key: IIQSJHUEZBTSAT-UHFFFAOYSA-N
- SMILES: O1C2=C(C([H])=C3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])(C([H])([H])C4C([H])=C([H])C(=C([H])C=4[H])OC4=C(C([H])=C([H])C(=C4[H])C([H])([H])C4([H])C5=C1C(=C(C([H])=C5C([H])([H])C([H])([H])N4C([H])([H])[H])OC([H])([H])[H])O[H])OC([H])([H])[H])C3=C2[H])OC([H])([H])[H]
Computed Properties
- Exact Mass: 608.28900
- Monoisotopic Mass: 608.28863700g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 8
- Heavy Atom Count: 45
- Rotatable Bond Count: 3
- Complexity: 963
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 2
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 72.9
- XLogP3: 6.1
Experimental Properties
- Color/Form: Cryst.
- Density: 1.2040
- Melting Point: Not available
- Boiling Point: 709.7°C at 760 mmHg
- Flash Point: 383.0±32.9 °C
- Refractive Index: 1.601
- PSA: 72.86000
- LogP: 6.73520
- Vapor Pressure: 0.0±2.3 mmHg at 25°C
(R)-Fangchinoline Security Information
- Signal Word:Warning
- Hazard Statement: H315; H319; H335
- Warning Statement: P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501
- Safety Instruction: H303+H313+H333
- Storage Condition:Store long-term at 2-8°C
(R)-Fangchinoline Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | F110200-20mg |
(R)-Fangchinoline |
33889-68-8 | ,>98% | 20mg |
¥205.90 | 2023-09-03 | |
| S e l l e c k ZHONG GUO | S3606-5mg |
Fangchinoline |
33889-68-8 | 99.89% | 5mg |
¥794.94 | 2023-09-15 | |
| SHANG HAI YUAN YE Biotechnology Co., Ltd. | B20388-20mg |
Isofangchinoline |
33889-68-8 | ,HPLC≥98% | 20mg |
¥220.00 | 2022-01-07 | |
| SHANG HAI YUAN YE Biotechnology Co., Ltd. | B20388-200mg |
Isofangchinoline |
33889-68-8 | ,HPLC≥98% | 200mg |
¥1480.00 | 2022-01-07 | |
| TRC | F102365-100mg |
Fangchinoline |
33889-68-8 | 100mg |
$ 97.00 | 2023-09-07 | ||
| TRC | F102365-250mg |
Fangchinoline |
33889-68-8 | 250mg |
$ 184.00 | 2023-09-07 | ||
| TRC | F102365-2.5g |
Fangchinoline |
33889-68-8 | 2.5g |
$ 1455.00 | 2023-09-07 | ||
| SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd. | F24911-20mg |
Isofangchinoline |
33889-68-8 | ,HPLC≥98% | 20mg |
¥218.0 | 2023-09-07 | |
| SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd. | F24910-20mg |
Isofangchinoline |
33889-68-8 | 98%() | 20mg |
¥208.0 | 2023-09-07 | |
| WU HAN AN JIE KAI Biomedical Technology Co., Ltd. | ajcn5572-20mg |
Fangchinoline |
33889-68-8 | 98% | 20mg |
¥1018.00 | 2023-09-07 |
(R)-Fangchinoline Related Literature
-
Albertus D. Handoko,Khoong Hong Khoo,Teck Leong Tan,Hongmei Jin,Zhi Wei Seh J. Mater. Chem. A, 2018,6, 21885-21890
-
Jason Wan Lab Chip, 2020,20, 4528-4538
-
Bo Wei,Zhenyu Liu,Chen Xie,Shu Yang,Wentao Tang,Aiwei Gu,Wing-Tak Wong,Ka-Leung Wong J. Mater. Chem. C, 2015,3, 12322-12327
-
Yong Ping Huang,Tao Tao,Zheng Chen,Wei Han,Ying Wu,Chunjiang Kuang,Shaoxiong Zhou,Ying Chen J. Mater. Chem. A, 2014,2, 18831-18837
-
Xinhuan Wang,Shuangfei Cai,Cui Qi Analyst, 2017,142, 2500-2506
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