Cas no 33574-02-6 ((IODOMETHYL)CYCLOPROPANE)

(Iodomethyl)cyclopropane is a versatile cyclopropane derivative featuring an iodomethyl functional group, which enhances its reactivity in organic synthesis. This compound is particularly valuable as a building block for cross-coupling reactions, nucleophilic substitutions, and cyclopropanation processes. Its strained cyclopropane ring and reactive C-I bond make it useful for constructing complex molecular frameworks, including pharmaceuticals and agrochemical intermediates. The compound's stability under controlled conditions ensures reliable handling, while its high purity allows for precise synthetic applications. (Iodomethyl)cyclopropane is commonly employed in medicinal chemistry and materials science due to its ability to introduce cyclopropyl motifs efficiently. Proper storage in a cool, dark environment is recommended to maintain its integrity.
(IODOMETHYL)CYCLOPROPANE structure
(IODOMETHYL)CYCLOPROPANE structure
Product Name:(IODOMETHYL)CYCLOPROPANE
CAS No:33574-02-6
MF:C4H7I
MW:182.002853631973
MDL:MFCD06410734
CID:294336
PubChem ID:2763048
Update Time:2025-10-07

(IODOMETHYL)CYCLOPROPANE Chemical and Physical Properties

Names and Identifiers

    • (IODOMETHYL)CYCLOPROPANE
    • Iodomethylcyclopropane
    • Cyclopropane,(iodomethyl)-
    • (cyclopropyl)methyl iodide
    • AmbkkkkK549
    • Cyclopropane,(iodomethyl)
    • cyclopropylcarbinyl iodide
    • 2-(Iodomethyl)cyclopropane
    • Cyclopropylmethyl iodide
    • AMY6123
    • FT-0763805
    • AS-9979
    • Iodomethylcyclopropane over Cu
    • Cyclopropane, (iodomethyl)-
    • EN300-211415
    • SCHEMBL171373
    • JHKJQWFHNIOUKY-UHFFFAOYSA-N
    • SY266775
    • (Iodomethyl)cyclopropane, >=96.0% (GC)
    • CS-0056033
    • 33574-02-6
    • DTXSID00376696
    • P19124
    • MFCD06410734
    • (Iodomethyl)cyclopropane, 95% (stab. with copper)
    • PB42571
    • AKOS006283240
    • DB-215147
    • DB-081381
    • iodomethyl-cyclopropane
    • MDL: MFCD06410734
    • Inchi: 1S/C4H7I/c5-3-4-1-2-4/h4H,1-3H2
    • InChI Key: JHKJQWFHNIOUKY-UHFFFAOYSA-N
    • SMILES: ICC1CC1

Computed Properties

  • Exact Mass: 181.95900
  • Monoisotopic Mass: 181.959
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 0
  • Heavy Atom Count: 5
  • Rotatable Bond Count: 1
  • Complexity: 30.6
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 0A^2
  • XLogP3: 2.6

Experimental Properties

  • Density: 1.954
  • Melting Point: 88-90 oC
  • Boiling Point: 142 oC
  • Flash Point: 57 oC
  • Refractive Index: n20/D 1.542
  • PSA: 0.00000
  • LogP: 1.83140
  • Sensitiveness: Light Sensitive

(IODOMETHYL)CYCLOPROPANE Security Information

  • Symbol: GHS07
  • Signal Word:Warning
  • Hazard Statement: H315-H319-H335
  • Warning Statement: P305+P351+P338
  • Hazardous Material transportation number:NONH for all modes of transport
  • WGK Germany:3
  • Hazard Category Code: 36/37/38
  • Safety Instruction: 26
  • Hazardous Material Identification: Xi

(IODOMETHYL)CYCLOPROPANE Customs Data

  • HS CODE:2903890090
  • Customs Data:

    China Customs Code:

    2903890090

    Overview:

    2903890090. Other naphthenic hydrocarbons\Halogenated derivatives of cycloalkenes or cycloterpene alkenes. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:5.5%. general tariff:30.0%

    Declaration elements:

    Product Name, component content, use to

    Summary:

    2903890090. halogenated derivatives of cyclanic, cyclenic or cyclotherpenic hydrocarbons. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

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(IODOMETHYL)CYCLOPROPANE Suppliers

Amadis Chemical Company Limited
Gold Member
Audited Supplier Audited Supplier
(CAS:33574-02-6)(IODOMETHYL)CYCLOPROPANE
Order Number:A1033063
Stock Status:in Stock
Quantity:25g
Purity:99%
Pricing Information Last Updated:Thursday, 29 August 2024 16:50
Price ($):438.0

Additional information on (IODOMETHYL)CYCLOPROPANE

Comprehensive Overview of (IODOMETHYL)CYCLOPROPANE (CAS No. 33574-02-6): Properties, Applications, and Industry Insights

(IODOMETHYL)CYCLOPROPANE (CAS No. 33574-02-6) is a specialized cyclopropane derivative widely recognized for its unique chemical structure and versatile applications in organic synthesis. This compound, featuring an iodomethyl functional group, has garnered significant attention in pharmaceutical research, agrochemical development, and material science due to its reactivity as a building block for complex molecular architectures. Its CAS registry number, 33574-02-6, serves as a critical identifier for researchers and regulatory compliance.

The growing demand for cyclopropane-based intermediates like (IODOMETHYL)CYCLOPROPANE aligns with trends in green chemistry and sustainable synthesis. Recent studies highlight its role in C-C bond formation reactions, particularly in cross-coupling methodologies such as Suzuki-Miyaura and Negishi reactions. Industry professionals frequently search for "iodomethyl cyclopropane synthesis" or "CAS 33574-02-6 applications," reflecting its relevance in modern drug discovery pipelines and catalysis research.

From a molecular perspective, the three-membered ring of cyclopropane introduces notable ring strain, which enhances the compound's reactivity. This property makes (IODOMETHYL)CYCLOPROPANE valuable for constructing sterically constrained bioactive molecules. Analytical techniques like NMR spectroscopy and mass spectrometry are essential for characterizing this compound, with its iodine atom providing a distinct spectroscopic signature.

In pharmaceutical contexts, researchers explore (IODOMETHYL)CYCLOPROPANE as a precursor for protease inhibitors and kinase modulators. Its incorporation into small-molecule libraries supports fragment-based drug design. Meanwhile, material scientists leverage its halogenated cyclopropane structure to develop advanced polymers with tailored thermal stability. These interdisciplinary applications address trending queries such as "halogenated cyclopropanes in drug design" and "33574-02-6 material science uses."

Handling (IODOMETHYL)CYCLOPROPANE requires adherence to standard laboratory safety protocols, including inert atmosphere techniques for moisture-sensitive reactions. While not classified as hazardous under normal conditions, proper storage in amber glass containers under nitrogen is recommended to maintain stability. Suppliers often provide technical data sheets detailing its physicochemical properties, including melting point, solubility, and purity specifications.

The commercial availability of CAS 33574-02-6 through specialty chemical vendors has expanded with the rise of custom synthesis services. Procurement strategies increasingly focus on scalable production routes, with manufacturers optimizing iodination methodologies to improve yield. Recent patents disclose novel applications in click chemistry and bioorthogonal labeling, further driving market interest.

Environmental considerations for (IODOMETHYL)CYCLOPROPANE emphasize waste minimization strategies in industrial settings. Researchers are investigating catalytic recycling of iodine byproducts, aligning with circular economy principles. Such developments respond to search trends like "green synthesis of iodomethyl compounds" and "33574-02-6 environmental impact," demonstrating the compound's evolving role in sustainable chemistry.

Future research directions may explore enantioselective variants of (IODOMETHYL)CYCLOPROPANE for chiral synthesis applications. Computational chemistry studies predict potential in metal-organic frameworks (MOFs) and energy storage materials. As the scientific community prioritizes atom-efficient transformations, this compound's unique attributes position it as a valuable tool for next-generation molecular engineering.

Recommended suppliers
Amadis Chemical Company Limited
(CAS:33574-02-6)(IODOMETHYL)CYCLOPROPANE
A1033063
Purity:99%
Quantity:25g
Price ($):438.0
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