Cas no 3334-05-2 (Tetrahydrothiophen-3-ol)

Tetrahydrothiophen-3-ol is a sulfur-containing heterocyclic compound characterized by a saturated five-membered ring with a hydroxyl group at the 3-position. This structure imparts unique reactivity and polarity, making it a valuable intermediate in organic synthesis and pharmaceutical applications. Its thioether functionality enhances chelating properties, while the hydroxyl group allows for further derivatization, such as esterification or etherification. The compound’s stability and solubility in common organic solvents facilitate its use in catalytic processes and as a building block for more complex molecules. Its versatility in medicinal chemistry, particularly in the development of bioactive compounds, underscores its significance in research and industrial settings.
Tetrahydrothiophen-3-ol structure
Tetrahydrothiophen-3-ol structure
Product Name:Tetrahydrothiophen-3-ol
CAS No:3334-05-2
MF:C4H8OS
MW:104.170720100403
MDL:MFCD00121060
CID:315086
PubChem ID:315652
Update Time:2025-05-27

Tetrahydrothiophen-3-ol Chemical and Physical Properties

Names and Identifiers

    • Tetrahydrothiophen-3-ol
    • TETRAHYDRO-THIOPHEN-3-OL
    • Thiophene-3-ol,tetrahydro-
    • (R)-tetrahydrothiophen-3-ol
    • 3(S)-hydroxytetrahydrothiophene
    • 3-hydroxytetrahydrothiofuran
    • 3-hydroxy-tetrahydrothiophene
    • 3-hydroxythiolane
    • tetrahydro-3-thiopheneol(SALTDATA: FREE)
    • 4-(1H-1,2,4-TRIAZOL-1-YLMETHYL)BENZOICACID
    • AM20090505
    • AKOS000249684
    • Thiophene-3-ol, tetrahydro-
    • thiolan-3-ol
    • Thiophene-3-ol, tetrahydro-, (3R)-
    • NSC-241152
    • MFCD00121060
    • AKOS016051617
    • SB12141
    • A839585
    • SCHEMBL69923
    • 3334-05-2
    • FT-0650764
    • Tetrahydro-3-thiophenol #
    • tetrahydro-3-thiopheneol
    • SY185762
    • EN300-66691
    • 3-Hydroxytetrahydrothiophene
    • CS-0185375
    • 3-thiolanol
    • NSC241152
    • AS-54855
    • tetrahydrothiophene-3-ol
    • 79107-71-4
    • Thiacyclopentane-3-ol
    • FT-0653314
    • W10543
    • Z335244836
    • DB-007915
    • MDL: MFCD00121060
    • Inchi: 1S/C4H8OS/c5-4-1-2-6-3-4/h4-5H,1-3H2
    • InChI Key: BJYXNFYVCZIXQC-UHFFFAOYSA-N
    • SMILES: S1CCC(C1)O

Computed Properties

  • Exact Mass: 104.02964
  • Monoisotopic Mass: 104.03
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 1
  • Heavy Atom Count: 6
  • Rotatable Bond Count: 0
  • Complexity: 46.8
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 1
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 45.5A^2
  • XLogP3: 0.4

Experimental Properties

  • Density: 1.222
  • Boiling Point: 201.2°Cat760mmHg
  • Flash Point: 98.7°C
  • Refractive Index: 1.576
  • PSA: 20.23
  • LogP: 0.48420

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