Cas no 32908-36-4 ((S)-cyclohexyl(phenyl)methanamine)

(S)-Cyclohexyl(phenyl)methanamine is a chiral amine compound featuring a cyclohexyl and phenyl substituent on the central carbon atom. Its stereospecific (S)-configuration makes it valuable as a chiral building block in asymmetric synthesis, particularly for pharmaceuticals and fine chemicals. The rigid cyclohexyl group enhances conformational stability, while the phenyl ring provides opportunities for further functionalization. This compound is commonly employed as a ligand or intermediate in catalytic reactions, including enantioselective hydrogenations and C–C bond formations. Its high purity and well-defined stereochemistry ensure reproducibility in synthetic applications. Storage under inert conditions is recommended to maintain stability.
(S)-cyclohexyl(phenyl)methanamine structure
32908-36-4 structure
Product Name:(S)-cyclohexyl(phenyl)methanamine
CAS No:32908-36-4
MF:C13H19N
MW:189.29666352272
MDL:MFCD20544743
CID:1454108
PubChem ID:12280950
Update Time:2025-11-02

(S)-cyclohexyl(phenyl)methanamine Chemical and Physical Properties

Names and Identifiers

    • Benzenemethanamine, a-cyclohexyl-, (S)-
    • (R)-cyclohexyl(phenyl)methanamine
    • (+)-α-Cicloesilbenzilamin
    • (S)-cyclohexyl(phenyl)methanamine
    • Benzenemethanamine, α-cyclohexyl-, (αS)-
    • MDL: MFCD20544743
    • Inchi: 1S/C13H19N/c14-13(11-7-3-1-4-8-11)12-9-5-2-6-10-12/h1,3-4,7-8,12-13H,2,5-6,9-10,14H2/t13-/m1/s1
    • InChI Key: JQCBKIHKSZUZKT-CYBMUJFWSA-N
    • SMILES: C1([C@H](C2CCCCC2)N)=CC=CC=C1

Computed Properties

  • Exact Mass: 189.15200

Experimental Properties

  • Density: 1.000±0.06 g/cm3(Predicted)
  • Boiling Point: 83-85 °C(Press: 0.6 Torr)
  • PSA: 26.02000
  • LogP: 3.96700
  • pka: 9.30±0.10(Predicted)

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Additional information on (S)-cyclohexyl(phenyl)methanamine

Exploring (S)-Cyclohexyl(phenyl)methanamine (CAS No. 32908-36-4): Properties, Applications, and Market Insights

(S)-Cyclohexyl(phenyl)methanamine (CAS No. 32908-36-4) is a chiral amine compound with significant importance in pharmaceutical and chemical research. This compound, characterized by its cyclohexyl and phenyl groups, is widely studied for its unique stereochemical properties and potential applications. The (S)-enantiomer of this molecule is particularly notable for its role in asymmetric synthesis and drug development.

The molecular structure of (S)-cyclohexyl(phenyl)methanamine features a chiral center, making it a valuable building block in the synthesis of optically active compounds. Researchers often utilize this compound in the development of chiral catalysts and pharmaceutical intermediates. Its high enantiomeric purity and stability under various conditions make it a preferred choice for many synthetic applications.

In recent years, the demand for chiral amines like (S)-cyclohexyl(phenyl)methanamine has grown significantly, driven by advancements in asymmetric synthesis and the pharmaceutical industry's focus on enantioselective drugs. This compound is often searched in relation to topics such as "chiral amine synthesis", "enantioselective catalysis", and "pharmaceutical intermediates", reflecting its relevance in current research trends.

One of the key applications of (S)-cyclohexyl(phenyl)methanamine is in the preparation of active pharmaceutical ingredients (APIs). Its ability to serve as a chiral auxiliary or ligand in metal-catalyzed reactions has made it indispensable in modern drug discovery. Additionally, its use in organocatalysis and stereoselective transformations has been widely documented in scientific literature.

The synthesis of (S)-cyclohexyl(phenyl)methanamine typically involves enantioselective reduction or resolution techniques to achieve high optical purity. Recent innovations in biocatalysis and green chemistry have also explored more sustainable routes to produce this compound, aligning with the growing emphasis on environmentally friendly synthesis.

Market analysis indicates that the global demand for (S)-cyclohexyl(phenyl)methanamine is expected to rise, particularly in regions with strong pharmaceutical and fine chemical industries. Researchers and manufacturers are increasingly interested in cost-effective synthesis methods and scalable production processes for this compound, as reflected in frequent searches for "bulk (S)-cyclohexyl(phenyl)methanamine suppliers" and "CAS 32908-36-4 price trends".

From a regulatory perspective, (S)-cyclohexyl(phenyl)methanamine is generally regarded as safe for research and industrial use when handled according to standard laboratory protocols. However, users often search for "(S)-cyclohexyl(phenyl)methanamine safety data" and "CAS 32908-36-4 handling precautions", emphasizing the importance of proper chemical management practices.

In conclusion, (S)-Cyclohexyl(phenyl)methanamine (CAS No. 32908-36-4) represents an important chiral building block with diverse applications in pharmaceutical chemistry and beyond. Its unique structural features and synthetic versatility continue to make it a subject of active research and commercial interest. As the field of asymmetric synthesis evolves, this compound is likely to maintain its significance in the development of novel chiral compounds and therapeutic agents.

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