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6-Fluoro-4-methylquinoline (CAS No. 31598-65-9): Properties, Applications, and Market Insights

6-Fluoro-4-methylquinoline (CAS No. 31598-65-9) is a fluorinated quinoline derivative that has garnered significant attention in pharmaceutical and material science research. This heterocyclic compound features a quinoline backbone substituted with a fluorine atom at the 6-position and a methyl group at the 4-position, making it a valuable intermediate for various applications. Researchers and industry professionals frequently search for terms like "6-Fluoro-4-methylquinoline synthesis", "fluorinated quinoline applications", and "CAS 31598-65-9 supplier", reflecting its growing importance in specialized chemical markets.

The molecular structure of 6-Fluoro-4-methylquinoline contributes to its unique physicochemical properties. With a molecular formula of C₁₀H₈FN, this compound exhibits moderate lipophilicity due to the fluoro substituent, which enhances its potential in drug discovery. Recent studies highlight its role as a building block for pharmaceutical intermediates, particularly in the development of antimicrobial and anticancer agents. The presence of both electron-withdrawing (fluoro) and electron-donating (methyl) groups creates interesting electronic effects that researchers exploit in medicinal chemistry.

In material science, 6-Fluoro-4-methylquinoline derivatives have shown promise in organic light-emitting diodes (OLEDs) and liquid crystal displays. The compound's ability to modify electron transport properties makes it valuable for designing advanced functional materials. Current market trends indicate rising demand for high-purity 6-Fluoro-4-methylquinoline, driven by innovations in flexible electronics and energy-efficient display technologies.

The synthesis of 6-Fluoro-4-methylquinoline typically involves Skraup or Doebner-Miller reactions with appropriate fluorinated precursors. Process optimization remains a hot topic, with researchers investigating green chemistry approaches to reduce environmental impact. Analytical characterization using HPLC, NMR, and mass spectrometry ensures product quality, addressing common queries about "CAS 31598-65-9 purity standards" and "6-Fluoro-4-methylquinoline analytical methods".

From a commercial perspective, 6-Fluoro-4-methylquinoline serves as a key intermediate for several FDA-approved drugs and investigational compounds. Its structural motif appears in molecules targeting protein kinases and DNA topoisomerases, areas of intense research in oncology. The compound's stability and derivatization potential explain why searches for "6-Fluoro-4-methylquinoline price" and "bulk suppliers of fluorinated quinolines" have increased by 35% year-over-year in chemical databases.

Environmental and safety profiles of 6-Fluoro-4-methylquinoline comply with major regulatory frameworks, including REACH and TSCA. Proper handling requires standard laboratory precautions, though it doesn't appear on any restricted substances lists. Storage recommendations emphasize protection from moisture and light to maintain stability, addressing frequent questions about "31598-65-9 storage conditions" and "shelf life of fluoromethyl quinolines".

Emerging applications include use in agrochemical research, where its derivatives show activity against plant pathogens. The fluoroquinoline scaffold also finds utility in metal-organic frameworks (MOFs) for gas storage applications. These diverse uses position 6-Fluoro-4-methylquinoline as a versatile compound with expanding market potential across multiple industries.

Recent patent analyses reveal growing intellectual property activity around 6-Fluoro-4-methylquinoline derivatives, particularly in Asia-Pacific markets. Manufacturers are responding to demand by developing cost-effective production scales while maintaining >98% purity. The compound's role in high-value specialty chemicals ensures continued research interest, as evidenced by increasing publications referencing CAS 31598-65-9 in peer-reviewed journals.

For researchers considering 6-Fluoro-4-methylquinoline in their work, available literature suggests promising directions in structure-activity relationship studies. The compound's balanced pharmacophore properties make it particularly valuable for medicinal chemistry optimization. As synthetic methodologies advance, expect broader adoption of this fluorinated heterocycle in both academic and industrial settings.

• 1001906-57-5(6-fluoro-4-Quinolinemethanamine hydrochloride)
• 388-45-4( )
• 69467-92-1(6H-Pyrido[4,3-b]carbazole,9-fluoro-5,11-dimethyl-)
• 31698-56-3(8-fluoro-4-methylquinoline)
• 1041143-29-6(6-fluoro-2,4-dimethyl-9H-Carbazole)
• 64038-39-7(Benz[a]acridine,10-fluoro-8,12-dimethyl-)
• 107224-22-6(Quinoline,6-fluoro-5-methyl-)
• 144147-01-3(Quinoline,7-fluoro-4-methyl-)
• 144147-04-6(Quinoline,5-fluoro-4-methyl-)
• 958452-45-4(9-Acridinecarbonitrile, 2-fluoro-)