Cas no 309962-67-2 (tert-butyl N-methyl-N-[(3R)-piperidin-3-yl]carbamate)

Tert-butyl N-methyl-N-[(3R)-piperidin-3-yl]carbamate is a chiral piperidine derivative commonly employed as a key intermediate in pharmaceutical synthesis. Its stereospecific (3R) configuration ensures high enantiopurity, making it valuable for the production of optically active compounds. The tert-butyloxycarbonyl (Boc) protecting group enhances stability and facilitates selective deprotection under mild acidic conditions, enabling controlled functionalization. This compound is particularly useful in medicinal chemistry for the development of receptor-targeting molecules, including CNS-active drugs and enzyme inhibitors. Its well-defined structure and compatibility with standard coupling reactions contribute to efficient synthetic workflows. The compound is typically supplied with rigorous purity standards to ensure reproducibility in research and industrial applications.
tert-butyl N-methyl-N-[(3R)-piperidin-3-yl]carbamate structure
309962-67-2 structure
Product Name:tert-butyl N-methyl-N-[(3R)-piperidin-3-yl]carbamate
CAS No:309962-67-2
MF:C11H22N2O2
MW:214.304583072662
MDL:MFCD09878596
CID:304032
PubChem ID:28875356
Update Time:2025-10-31

tert-butyl N-methyl-N-[(3R)-piperidin-3-yl]carbamate Chemical and Physical Properties

Names and Identifiers

    • (R)-tert-Butyl methyl(piperidin-3-yl)carbamate
    • (R)-3-N-Boc-3-(methylamino)piperidine
    • Carbamic acid, methyl(3R)-3-piperidinyl-, 1,1-dimethylethyl ester (9CI)
    • R-3-N-Boc-3-(Methylamino)piperidine
    • tert-butyl (R)-methyl(piperidin-3-yl)carbamate
    • Methyl-(R)-piperidin-3-yl-carbamic acid tert-butyl ester
    • R-3-Boc-3-methylaminopiperidine
    • tert-butyl methyl[(3R)-piperidin-3-yl]carbamate
    • tert-butyl methyl[(3R)-piperidinyl]carbamate
    • tert-butyl N-methyl-N-[(3R)-piperidin-3-yl]carbamate
    • Carbamic acid, N-methyl-N-(3R)-3-piperidinyl-, 1,1-dimethylethyl ester
    • (R)-Tert-Butylmethyl(Piperidin-3-yl)Carbamate
    • (R)-3-Boc-3-methylaminopiperidine
    • KS-0
    • LCZC2857
    • AKOS007930615
    • RTXNDTNDOHQMTI-SECBINFHSA-N
    • methyl (R)-piperidin-3-ylcarbamic acid tert-butyl ester
    • A25772
    • AM90337
    • SCHEMBL1267151
    • DTXSID00651733
    • 309962-67-2
    • LS-1028
    • AC-24266
    • MFCD09878596
    • CS-B0443
    • MDL: MFCD09878596
    • Inchi: 1S/C11H22N2O2/c1-11(2,3)15-10(14)13(4)9-6-5-7-12-8-9/h9,12H,5-8H2,1-4H3/t9-/m1/s1
    • InChI Key: RTXNDTNDOHQMTI-SECBINFHSA-N
    • SMILES: O(C(C)(C)C)C(N(C)[C@H]1CNCCC1)=O

Computed Properties

  • Exact Mass: 214.16800
  • Monoisotopic Mass: 214.168
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 15
  • Rotatable Bond Count: 3
  • Complexity: 223
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 1
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 41.6
  • XLogP3: 1.2

Experimental Properties

  • Color/Form: No data avaiable
  • Density: 1.01
  • Melting Point: No data available
  • Boiling Point: 288 oC
  • Flash Point: 128 oC
  • Refractive Index: 1.485
  • PSA: 41.57000
  • LogP: 1.93410
  • Vapor Pressure: No data available

tert-butyl N-methyl-N-[(3R)-piperidin-3-yl]carbamate Pricemore >>

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abcr
AB443094-250 mg
(R)-tert-Butyl methyl(piperidin-3-yl)carbamate, 95%; .
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abcr
AB443094-1 g
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abcr
AB443094-5 g
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abcr
AB443094-10 g
(R)-tert-Butyl methyl(piperidin-3-yl)carbamate, 95%; .
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abcr
AB443094-25 g
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SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd.
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tert-butyl N-methyl-N-[(3R)-piperidin-3-yl]carbamate Production Method

Additional information on tert-butyl N-methyl-N-[(3R)-piperidin-3-yl]carbamate

Professional Introduction to Compound with CAS No. 309962-67-2 and Product Name: *tert-butyl N-methyl-N-[(3R)-piperidin-3-yl]carbamate*

The compound with the CAS number 309962-67-2 and the product name tert-butyl N-methyl-N-[(3R)-piperidin-3-yl]carbamate represents a significant advancement in the field of medicinal chemistry. This compound, characterized by its unique structural and functional properties, has garnered considerable attention due to its potential applications in the development of novel therapeutic agents. The detailed analysis of its chemical structure, synthesis methods, and biological activities provides valuable insights into its utility in pharmaceutical research.

In recent years, there has been a growing interest in the development of carbamate-based compounds for their diverse pharmacological properties. The carbamate functional group, particularly when incorporated into a piperidine scaffold, exhibits remarkable bioactivity. The specific configuration of the piperidine ring, denoted as (3R), plays a crucial role in determining the compound's interactions with biological targets. This stereochemical specificity is a key factor in its potential therapeutic efficacy.

The synthesis of tert-butyl N-methyl-N-[(3R)-piperidin-3-yl]carbamate involves a multi-step process that requires precise control over reaction conditions and reagent selection. Advanced synthetic methodologies, such as asymmetric hydrogenation and nucleophilic substitution reactions, are employed to achieve the desired stereochemical purity. These synthetic strategies not only highlight the compound's complexity but also underscore the expertise required to produce it on an industrial scale.

One of the most compelling aspects of this compound is its potential application in the treatment of neurological disorders. Research has demonstrated that carbamate derivatives can modulate neurotransmitter activity by interacting with specific receptors and enzymes. The (3R)-configuration of the piperidine ring enhances binding affinity to these targets, making it an attractive candidate for further investigation. Preclinical studies have shown promising results in animal models, suggesting that this compound may have therapeutic benefits in conditions such as epilepsy and Parkinson's disease.

The pharmacokinetic profile of tert-butyl N-methyl-N-[(3R)-piperidin-3-yl]carbamate is another critical factor that contributes to its potential clinical utility. Studies have indicated that this compound exhibits favorable solubility and metabolic stability, which are essential properties for any drug candidate. Additionally, its low toxicity profile suggests that it may be well-tolerated by patients, reducing the risk of adverse effects.

In conclusion, the compound with CAS number 309962-67-2 and the product name tert-butyl N-methyl-N-[(3R)-piperidin-3-yl]carbamate represents a significant advancement in medicinal chemistry. Its unique structural features, synthetic pathways, and biological activities make it a promising candidate for further research and development. As our understanding of its pharmacological properties continues to grow, this compound holds great potential for contributing to the treatment of various diseases.

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