Cas no 3084-40-0 (Diethyl P-(Hydroxymethyl)phosphonic Acid Ester)
Diethyl P-(Hydroxymethyl)phosphonic Acid Ester Chemical and Physical Properties
Names and Identifiers
-
- Diethyl (hydroxymethyl)phosphonate
- 4-Hydroxymethyldiethylphosphonate
- Diethyl hydroxymethylphosphonate
- (Hydroxymethyl)phosphonic acid diethyl ester
- (Hydroxymethyl)phosphonic acid diethyl ester Diethyl phosphonomethanol
- AURORA KA-1421
- diethyl hydroxy-methanephosphonate
- Diethyl Phosphonometanol
- Diethyl phosphonomethanol
- Phosphonicacid, (hydroxymethyl)-, diethyl ester (6CI,7CI,8CI,9CI)
- (Hydroxymethyl)phosphonate diethyl ester
- diethoxyphosphoryl-methanol
- diethyl hydroxylmethylphosphonate
- NS00028976
- Phosphonic acid, P-(hydroxymethyl)-, diethyl ester
- Diethyl(hydroxymethyl)phosphonate
- diethyl P-(hydroxymethyl)phosphonate
- AS-15772
- MFCD00014418
- diethoxyphosphorylmethanol
- Phosphonic acid, (hydroxymethyl)-, diethyl ester
- NR74SN9XT3
- EN300-258561
- A842986
- AKOS015951125
- Diethyl (hydroxymethyl)phosphonate, technical grade
- SY037754
- DTXSID6062838
- EINECS 221-391-6
- A820643
- FT-0602274
- UNII-NR74SN9XT3
- W-106926
- 3084-40-0
- (Hydroxymethyl)phosphonic acid, diethyl ester
- CS-W017818
- hydroxymethylphosphonic acid diethylester
- diethylhydroxymethylphosphonate
- hydroxymethyl phosphonic acid diethylester
- SCHEMBL246097
- hydroxymethyl-phosphonic acid diethyl ester
- D3813
- diethyl (hydroxymethyl) phosphonate
- diethyl hydroxymethanephosphonate
- DB-013137
- DTXCID9038268
- 221-391-6
- Diethyl P-(Hydroxymethyl)phosphonic Acid Ester
-
- MDL: MFCD00014418
- Inchi: 1S/C5H13O4P/c1-3-8-10(7,5-6)9-4-2/h6H,3-5H2,1-2H3
- InChI Key: RWIGWWBLTJLKMK-UHFFFAOYSA-N
- SMILES: P(CO)(=O)(OCC)OCC
Computed Properties
- Exact Mass: 168.05500
- Monoisotopic Mass: 168.055145
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 4
- Heavy Atom Count: 10
- Rotatable Bond Count: 5
- Complexity: 115
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Surface Charge: 0
- Tautomer Count: nothing
- XLogP3: -0.4
- Topological Polar Surface Area: 55.8
Experimental Properties
- Color/Form: Not determined
- Density: 1.14?g/mL?at 25?°C(lit.)
- Boiling Point: 105°C/0.2mmHg(lit.)
- Flash Point: Degrees Fahrenheit:>235.4°F
Degrees Celsius:>113°C - Refractive Index: n20/D 1.444(lit.)
- PSA: 65.57000
- LogP: 1.20230
- Solubility: Not determined
- Sensitiveness: Sensitivity to humidity and heat
- Vapor Pressure: 0.0±1.1 mmHg at 25°C
Diethyl P-(Hydroxymethyl)phosphonic Acid Ester Security Information
-
Symbol:
- Prompt:warning
- Signal Word:Warning
- Hazard Statement: H315-H319
- Warning Statement: P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
- Hazardous Material transportation number:NONH for all modes of transport
- WGK Germany:3
- Hazard Category Code: R36/37/38
- Safety Instruction: S37/39-S26
-
Hazardous Material Identification:
- Safety Term:S26;S37/39
- Risk Phrases:R36/37/38
- TSCA:Yes
- Storage Condition:0-10°C
Diethyl P-(Hydroxymethyl)phosphonic Acid Ester Customs Data
- HS CODE:2931900090
- Customs Data:
China Customs Code:
2931900090Overview:
2931900090. Other organic-Inorganic compound. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:AB(Customs clearance form for Inbound Goods,Customs clearance form for outbound goods). MFN tariff:6.5%. general tariff:30.0%
Summary:
2931900090. other organo-inorganic compounds. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0%
Diethyl P-(Hydroxymethyl)phosphonic Acid Ester Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| XI GE MA AO DE LI QI ( SHANG HAI ) MAO YI Co., Ltd. | 392626-25ML |
Diethyl P-(Hydroxymethyl)phosphonic Acid Ester |
3084-40-0 | 25ml |
¥2018.68 | 2023-12-07 | ||
| SHANG HAI MAI KE LIN SHENG HUA Technology Co., Ltd. | D808377-500g |
Diethyl(hydroxymethyl)phosphonate |
3084-40-0 | 97.0% | 500g |
748.00 | 2021-05-17 | |
| Fluorochem | 215179-1g |
Diethyl (hydroxymethyl)phosphonate |
3084-40-0 | 95% | 1g |
£10.00 | 2022-03-01 | |
| Fluorochem | 215179-10g |
Diethyl (hydroxymethyl)phosphonate |
3084-40-0 | 95% | 10g |
£20.00 | 2022-03-01 | |
| Fluorochem | 215179-25g |
Diethyl (hydroxymethyl)phosphonate |
3084-40-0 | 95% | 25g |
£35.00 | 2022-03-01 | |
| Fluorochem | 215179-100g |
Diethyl (hydroxymethyl)phosphonate |
3084-40-0 | 95% | 100g |
£70.00 | 2022-03-01 | |
| ChemScence | CS-W017818-500g |
Diethyl (hydroxymethyl)phosphonate |
3084-40-0 | 500g |
$114.0 | 2022-04-27 | ||
| ChemScence | CS-W017818-1000g |
Diethyl (hydroxymethyl)phosphonate |
3084-40-0 | 1000g |
$200.0 | 2021-09-02 | ||
| TRC | D474295-1g |
Diethyl P-(Hydroxymethyl)phosphonic Acid Ester |
3084-40-0 | 1g |
$ 50.00 | 2022-06-05 | ||
| TRC | D474295-5g |
Diethyl P-(Hydroxymethyl)phosphonic Acid Ester |
3084-40-0 | 5g |
$ 60.00 | 2022-06-05 |
Diethyl P-(Hydroxymethyl)phosphonic Acid Ester Suppliers
Diethyl P-(Hydroxymethyl)phosphonic Acid Ester Related Literature
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Yuming Zhao,Wen Zhu,Ying Wu,Lin Qu,Zhengping Liu,Ke Zhang Polym. Chem. 2016 7 6513
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Mudassir Iqbal,Jurriaan Huskens,Michal Sypula,Giuseppe Modolo,Willem Verboom New J. Chem. 2011 35 2591
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Peter J. Rayner,Ben. J. Tickner,Wissam Iali,Marianna Fekete,Alastair D. Robinson,Simon B. Duckett Chem. Sci. 2019 10 7709
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Peter J. Rayner,Ben. J. Tickner,Wissam Iali,Marianna Fekete,Alastair D. Robinson,Simon B. Duckett Chem. Sci. 2019 10 7709
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Saad Touqeer,Laura Ielo,Margherita Miele,Ernst Urban,Wolfgang Holzer,Vittorio Pace Org. Biomol. Chem. 2021 19 2425
Additional information on Diethyl P-(Hydroxymethyl)phosphonic Acid Ester
Introduction to Diethyl P-(Hydroxymethyl)phosphonic Acid Ester and Its Applications
Diethyl P-(Hydroxymethyl)phosphonic Acid Ester (CAS No: 3084-40-0) is a significant compound in the field of chemical and pharmaceutical research. This compound, characterized by its unique structural properties, has garnered considerable attention due to its versatile applications in various scientific domains. The Hydroxymethyl group and the phosphonic acid ester moiety contribute to its distinctive reactivity, making it a valuable intermediate in synthetic chemistry and a potential candidate for drug development.
The chemical structure of Diethyl P-(Hydroxymethyl)phosphonic Acid Ester consists of a phosphonic acid backbone with an ester group at one end and a Hydroxymethyl group at the other. This configuration imparts a balance of reactivity and stability, allowing it to participate in a wide range of chemical transformations. The presence of the ester group enhances its solubility in organic solvents, facilitating its use in various synthetic protocols.
In recent years, there has been growing interest in the applications of Diethyl P-(Hydroxymethyl)phosphonic Acid Ester, particularly in the development of novel pharmaceuticals. Its ability to act as a chelating agent makes it useful in the synthesis of metal-organic frameworks (MOFs) and coordination polymers. These materials have potential applications in catalysis, gas storage, and separation technologies.
The compound's role as an intermediate in organic synthesis has also been explored extensively. Researchers have leveraged its reactivity to develop new methodologies for constructing complex molecules. For instance, it has been used in the synthesis of phosphonate esters, which are crucial in the development of agrochemicals and pharmaceuticals. The Hydroxymethyl group provides a nucleophilic site that can be selectively modified, enabling the construction of diverse molecular architectures.
One of the most exciting areas where Diethyl P-(Hydroxymethyl)phosphonic Acid Ester is making an impact is in drug discovery. Phosphonate compounds have shown promise as inhibitors of enzymes involved in cancer metabolism. The ester functionality allows for easy derivatization, enabling the creation of libraries of compounds that can be screened for biological activity. Recent studies have highlighted its potential as an anti-inflammatory agent, with preliminary findings suggesting that derivatives of this compound may modulate inflammatory pathways effectively.
The compound's stability under various conditions makes it an attractive choice for industrial applications as well. It can be stored for extended periods without significant degradation, ensuring consistency in its use across different processes. This stability is particularly important in pharmaceutical manufacturing, where batch-to-batch consistency is critical.
The environmental impact of using Diethyl P-(Hydroxymethyl)phosphonic Acid Ester has also been a focus of research. Efforts have been made to develop greener synthetic routes that minimize waste and reduce energy consumption. These efforts align with the broader goal of sustainable chemistry, which aims to develop processes that are environmentally friendly while maintaining high efficiency.
In conclusion, Diethyl P-(Hydroxymethyl)phosphonic Acid Ester (CAS No: 3084-40-0) is a multifaceted compound with significant potential across multiple scientific disciplines. Its unique structural features and reactivity make it a valuable tool in synthetic chemistry, drug development, and material science. As research continues to uncover new applications for this compound, its importance is likely to grow further.
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