Cas no 10419-80-4 (Diethyl (ethoxymethyl)phosphonate)

Diethyl (ethoxymethyl)phosphonate is a versatile organophosphorus compound with applications in organic synthesis and pharmaceutical intermediates. Its key advantages include its role as a phosphorylating agent, enabling efficient introduction of phosphonate groups into target molecules. The ethoxymethyl moiety enhances reactivity and solubility in organic solvents, facilitating diverse transformations. This compound is particularly useful in Horner-Wadsworth-Emmons reactions for olefination and in the synthesis of bioactive molecules. Its stability under standard conditions and compatibility with various reaction conditions make it a reliable reagent for researchers. Proper handling is required due to its sensitivity to moisture and potential reactivity with strong acids or bases.
Diethyl (ethoxymethyl)phosphonate structure
10419-80-4 structure
Product Name:Diethyl (ethoxymethyl)phosphonate
CAS No:10419-80-4
MF:C7H17O4P
MW:196.181243658066
MDL:MFCD00137939
CID:1141855
PubChem ID:354333738
Update Time:2025-06-27

Diethyl (ethoxymethyl)phosphonate Chemical and Physical Properties

Names and Identifiers

    • Phosphonic acid, (ethoxymethyl)-, diethyl ester
    • Diethyl (Ethoxymethyl)phosphonate
    • 1-(diethoxyphosphorylmethoxy)ethane
    • Aethoxymethyl-phosphonsaeure-diaethylester
    • diethyl ethoxymethylphosphonate
    • ethoxymethyl-phosphonic acid diethyl ester
    • Ethoxymethyl-phosphonsaeure-diethylester
    • (Ethoxymethyl)phosphonic Acid Diethyl Ester
    • D5095
    • Diethyl(ethoxymethyl)phosphonate
    • MFCD00137939
    • D90365
    • AKOS037646220
    • SCHEMBL7940743
    • DTXSID60520370
    • AS-67371
    • 10419-80-4
    • Diethyl (ethoxymethyl)phosphonate
    • MDL: MFCD00137939
    • Inchi: 1S/C7H17O4P/c1-4-9-7-12(8,10-5-2)11-6-3/h4-7H2,1-3H3
    • InChI Key: PELDURRTQRGRMV-UHFFFAOYSA-N
    • SMILES: P(COCC)(=O)(OCC)OCC

Computed Properties

  • Exact Mass: 196.08600
  • Monoisotopic Mass: 196.08644602g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 12
  • Rotatable Bond Count: 7
  • Complexity: 138
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 44.8
  • XLogP3: 0.5

Experimental Properties

  • Boiling Point: 103°C/10mmHg(lit.)
  • PSA: 54.57000
  • LogP: 2.24650

Diethyl (ethoxymethyl)phosphonate Security Information

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Diethyl (ethoxymethyl)phosphonate Suppliers

Amadis Chemical Company Limited
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(CAS:10419-80-4)Diethyl (ethoxymethyl)phosphonate
Order Number:A1012051
Stock Status:in Stock
Quantity:25g
Purity:99%
Pricing Information Last Updated:Thursday, 29 August 2024 15:12
Price ($):301.0

Additional information on Diethyl (ethoxymethyl)phosphonate

Comprehensive Guide to Diethyl (ethoxymethyl)phosphonate (CAS No. 10419-80-4): Properties, Applications, and Innovations

Diethyl (ethoxymethyl)phosphonate (CAS No. 10419-80-4) is a specialized organophosphorus compound with a wide range of applications in organic synthesis, pharmaceuticals, and material science. Known for its unique phosphonate ester structure, this chemical has garnered significant attention due to its versatility as a building block in modern chemistry. Researchers and industries value its role in facilitating C-P bond formation, a critical step in synthesizing bioactive molecules and advanced materials.

The compound's molecular formula, C7H17O4P, highlights its ethoxy and phosphonate functional groups, which contribute to its reactivity and solubility in organic solvents. Its CAS number 10419-80-4 is frequently searched in chemical databases, reflecting its importance in academic and industrial research. Recent trends show growing interest in sustainable synthesis methods, aligning with global demands for greener chemistry. Diethyl (ethoxymethyl)phosphonate is often discussed in the context of atom-efficient reactions and catalytic processes, making it a hotspot for innovation.

One of the most searched questions about this compound revolves around its synthetic applications. For instance, it serves as a key intermediate in the preparation of α-aminophosphonates, which are pivotal in drug discovery for their bioactivity. Another trending topic is its use in flame retardants and coating additives, where its phosphorus content enhances material properties. These applications are frequently explored in patents and scientific literature, driving further interest in CAS 10419-80-4.

From a technical perspective, Diethyl (ethoxymethyl)phosphonate exhibits stability under standard conditions but requires careful handling due to its sensitivity to moisture. Its boiling point and refractive index are often cited in purity assessments, ensuring quality control in industrial batches. Analytical techniques like NMR spectroscopy and GC-MS are commonly employed to characterize this compound, addressing another frequent query among researchers.

In the context of green chemistry, recent studies focus on optimizing the synthesis of Diethyl (ethoxymethyl)phosphonate to reduce waste and energy consumption. This aligns with broader industry shifts toward circular economy principles. Additionally, its potential in agrochemical formulations has sparked discussions about eco-friendly pest control solutions, a trending topic in sustainable agriculture.

As the demand for high-performance chemicals grows, Diethyl (ethoxymethyl)phosphonate continues to be a subject of cutting-edge research. Its compatibility with microwave-assisted synthesis and flow chemistry techniques positions it as a forward-looking candidate for scalable production. For those searching "CAS 10419-80-4 suppliers" or "phosphonate derivatives uses," this compound represents a bridge between traditional chemistry and modern technological advancements.

Recommended suppliers
Amadis Chemical Company Limited
(CAS:10419-80-4)Diethyl (ethoxymethyl)phosphonate
A1012051
Purity:99%
Quantity:25g
Price ($):301.0
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