Cas no 30511-77-4 ((2E,4Z)-5-(1,3-dioxaindan-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one)

(2E,4Z)-5-(1,3-dioxaindan-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one is a structurally complex enone derivative featuring a conjugated diene system and a 1,3-dioxaindane moiety. Its unique (2E,4Z) configuration enhances reactivity in Michael addition and cycloaddition reactions, making it valuable in synthetic organic chemistry. The piperidinyl group contributes to solubility in polar aprotic solvents, facilitating purification and downstream functionalization. The 1,3-dioxaindane unit provides stability while allowing selective deprotection for further modifications. This compound is particularly useful as an intermediate in pharmaceuticals and agrochemicals, where its conjugated system enables efficient scaffold diversification. Its balanced lipophilicity and steric profile make it suitable for cross-coupling and asymmetric catalysis applications.
(2E,4Z)-5-(1,3-dioxaindan-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one structure
30511-77-4 structure
Product Name:(2E,4Z)-5-(1,3-dioxaindan-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one
CAS No:30511-77-4
MF:C17H19NO3
MW:285.337664842606
CID:314318
PubChem ID:1548914
Update Time:2025-10-31

(2E,4Z)-5-(1,3-dioxaindan-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one Chemical and Physical Properties

Names and Identifiers

    • 2,4-Pentadien-1-one,5-(1,3-benzodioxol-5-yl)-1-(1-piperidinyl)-, (2E,4Z)-
    • Isochavicine
    • (2E,4Z)-5-(1,3-dioxaindan-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one
    • 2,4-PENTADIEN-1-ONE, 5-(1,3-BENZODIOXOL-5-YL)-1-(1-PIPERIDINYL)-, (2E,4Z)-
    • Q27287485
    • UNII-QTK8MIO5Z7
    • HY-N0144B
    • Piperidine, 1-(5-(1,3-benzodioxol-5-yl)-1-oxo-2,4-pentadienyl)-, (E,Z)-
    • 30511-77-4
    • CS-0040394
    • PIPERIDINE, 1-((2E,4Z)-5-(1,3-BENZODIOXOL-5-YL)-1-OXO-2,4-PENTADIENYL)-
    • EN300-27122036
    • QTK8MIO5Z7
    • SCHEMBL13151642
    • Inchi： 1S/C17H19NO3/c19-17(18-10-4-1-5-11-18)7-3-2-6-14-8-9-15-16(12-14)21-13-20-15/h2-3,6-9,12H,1,4-5,10-11,13H2/b6-2-,7-3+
    • InChI Key： MXXWOMGUGJBKIW-MFDSWNTHSA-N
    • SMILES： O=C(/C=C/C=C\C1C=CC2=C(C=1)OCO2)N1CCCCC1

Computed Properties

  • Exact Mass: 285.13657
  • Monoisotopic Mass: 285.13649347g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 21
  • Rotatable Bond Count: 3
  • Complexity: 412
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 2
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 3.5
  • Topological Polar Surface Area: 38.8?2

Experimental Properties

  • PSA: 38.77

(2E,4Z)-5-(1,3-dioxaindan-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
Enamine
EN300-27122036-0.05g
(2E,4Z)-5-(1,3-dioxaindan-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one
 30511-77-4 95.0%
0.05g
 $2755.0 2025-03-20
Ambeed
A2423106-5mg
Isochavicine
 30511-77-4 98%
5mg
 $609.0 2024-07-28

(2E,4Z)-5-(1,3-dioxaindan-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one Suppliers

Amadis Chemical Company Limited
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(CAS:30511-77-4)(2E,4Z)-5-(1,3-dioxaindan-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one
Order Number:A967690
Stock Status:in Stock
Quantity:5mg
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 16:20
Price ($):548.0

(2E,4Z)-5-(1,3-dioxaindan-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one Related Literature

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Additional information on (2E,4Z)-5-(1,3-dioxaindan-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one

Introduction to (2E,4Z)-5-(1,3-dioxaindan-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one (CAS No. 30511-77-4)

(2E,4Z)-5-(1,3-dioxaindan-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one (CAS No. 30511-77-4) is a complex organic compound that has garnered significant attention in the fields of medicinal chemistry and pharmaceutical research. This compound is characterized by its unique structural features, including a piperidine ring and a conjugated diene system, which contribute to its potential biological activities and therapeutic applications.

The chemical structure of (2E,4Z)-5-(1,3-dioxaindan-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one is composed of a penta-2,4-dienone backbone with a 1,3-dioxaindan substituent and a piperidine moiety. The presence of these functional groups imparts specific chemical properties and reactivity profiles that are crucial for its biological interactions. The conjugated diene system allows for the compound to participate in various chemical reactions and interactions with biological targets.

Recent studies have highlighted the potential of (2E,4Z)-5-(1,3-dioxaindan-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one in various therapeutic areas. One notable area of research is its anti-inflammatory properties. In vitro and in vivo studies have demonstrated that this compound can effectively inhibit the production of pro-inflammatory cytokines such as TNF-alpha and IL-6. This makes it a promising candidate for the treatment of inflammatory diseases such as rheumatoid arthritis and inflammatory bowel disease.

Furthermore, (2E,4Z)-5-(1,3-dioxaindan-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one has shown potential in cancer research. Studies have indicated that it can induce apoptosis in cancer cells through the activation of caspase pathways and the modulation of cell cycle regulatory proteins. This property has been particularly observed in breast cancer and colon cancer cell lines, suggesting its potential as an anticancer agent.

In addition to its anti-inflammatory and anticancer activities, (2E,4Z)-5-(1,3-dioxaindan-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one has also been investigated for its neuroprotective effects. Research has shown that it can protect neurons from oxidative stress-induced damage by scavenging free radicals and upregulating antioxidant enzymes such as superoxide dismutase (SOD) and catalase (CAT). These findings suggest that the compound may have therapeutic potential in neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease.

The pharmacokinetic properties of (2E,4Z)-5-(1,3-dioxaindan-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-one

To further explore the therapeutic potential of (2E,4Z)-5-(1,3-dioxaindan-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-one, several clinical trials are currently underway. These trials aim to evaluate the safety and efficacy of the compound in various disease models. Preliminary results from phase I clinical trials have shown that the compound is well-tolerated with no significant adverse effects observed at therapeutic doses.

In conclusion, (2E,4Z)-5-(1,3-dioxaindan-5-y\-l)-1-(piperidin\-y\-l)penta\-2\-,4\-dien\-y\-l)one (CAS No. 30511\-77\-4) is a promising compound with diverse biological activities and therapeutic applications. Its unique chemical structure and favorable pharmacokinetic properties make it an attractive candidate for further development in medicinal chemistry and pharmaceutical research. Ongoing studies continue to uncover new insights into its mechanisms of action and potential clinical uses.

30511-77-4 ((2E,4Z)-5-(1,3-dioxaindan-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one) Related Products

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Amadis Chemical Company Limited
(CAS:30511-77-4)(2E,4Z)-5-(1,3-dioxaindan-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one
A967690
Purity:99%
Quantity:5mg
Price ($):548.0
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