Cas no 7780-20-3 (5-(1,3-dioxaindan-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one)

5-(1,3-Dioxaindan-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one is a structurally distinct chemical compound featuring a conjugated diene system linked to a 1,3-dioxaindane moiety and a piperidine-derived ketone. This configuration imparts unique electronic and steric properties, making it a valuable intermediate in organic synthesis, particularly for the development of pharmacologically active molecules. The compound's extended π-conjugation enhances its reactivity in cycloaddition and nucleophilic addition reactions, while the dioxaindane group contributes to stability and solubility in polar solvents. Its modular structure allows for further functionalization, offering versatility in medicinal chemistry and materials science applications. The presence of the piperidinyl ketone moiety also suggests potential bioactivity, warranting further investigation in drug discovery.
5-(1,3-dioxaindan-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one structure
7780-20-3 structure
Product Name:5-(1,3-dioxaindan-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one
CAS No:7780-20-3
MF:C17H19NO3
MW:285.337664842606
MDL:MFCD00005839
CID:47810
PubChem ID:638024
Update Time:2025-10-19

5-(1,3-dioxaindan-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one Chemical and Physical Properties

Names and Identifiers

    • Piperine
    • 1-[5-(1,3-Benzodioxol-5-yl)-1-oxo-2,4-pentadienyl]piperidine
    • Piperidine, 1-[5-(3,4-methylenedioxyphenyl)-1-oxo-2,4-pentadienyl]-
    • 5-(1,3-dioxaindan-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one
    • Spectrum4_000708
    • Spectrum3_000868
    • NS00076855
    • KBioGR_001235
    • KBio2_003371
    • KBio1_000954
    • CHEMBL3188765
    • NCGC00094872-08
    • Bioperine;1-Piperoylpiperidine
    • Prestwick0_000474
    • Prestwick1_000474
    • SPBio_000177
    • SY048497
    • SB41065
    • Spectrum2_000049
    • SMR001548271
    • FT-0608276
    • KBio3_002015
    • Piperidine, 1-(5-(1,3-benzodioxol-5-yl)-1-oxo-2,4-pentadienyl)-
    • KBio2_000803
    • SPBio_002547
    • MLS006011979
    • Spectrum_000323
    • KBioSS_000803
    • DivK1c_000954
    • NINDS_000954
    • DTXSID50859166
    • HMS3656M07
    • 5-(1,3-benzodioxol-5-yl)-1-piperidin-1-ylpenta-2,4-dien-1-one
    • KBio2_005939
    • 2,4-Pentadien-1-one, 5-(1,3-benzodioxol-5-yl)-1-(1-piperidinyl)-, (2E,4E)-
    • 5-(3,4-methylenedioxyphenyl)-2,4-pentadienoylpiperidine
    • Piperidine
    • MDL： MFCD00005839
    • Inchi： 1S/C17H19NO3/c19-17(18-10-4-1-5-11-18)7-3-2-6-14-8-9-15-16(12-14)21-13-20-15/h2-3,6-9,12H,1,4-5,10-11,13H2
    • InChI Key： MXXWOMGUGJBKIW-UHFFFAOYSA-N
    • SMILES： O=C(C=CC=CC1C=CC2=C(C=1)OCO2)N1CCCCC1

Computed Properties

  • Exact Mass: 285.136493
  • Monoisotopic Mass: 285.136493
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 21
  • Rotatable Bond Count: 3
  • Complexity: 412
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 2
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 3.5
  • Topological Polar Surface Area: 38.8

Experimental Properties

  • Color/Form: Yellowish powder
  • Melting Point: 131.5 °C
  • PSA: 38.77000
  • LogP: 2.93510

5-(1,3-dioxaindan-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one Pricemore >>

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5-(1,3-dioxaindan-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one Suppliers

Tiancheng Chemical (Jiangsu) Co., Ltd
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(CAS:7780-20-3)Piperine
Order Number:LE12380
Stock Status:in Stock
Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Friday, 20 June 2025 12:07
Price ($):discuss personally

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Additional information on 5-(1,3-dioxaindan-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one

Introduction to 5-(1,3-dioxaindan-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one (CAS No. 7780-20-3)

5-(1,3-dioxaindan-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one (CAS No. 7780-20-3) is a complex organic compound that has garnered significant attention in the fields of medicinal chemistry and pharmaceutical research. This compound, characterized by its unique structural features, has shown promising potential in various therapeutic applications. This article aims to provide a comprehensive overview of the compound, including its chemical structure, synthesis methods, biological activities, and recent advancements in its research and development.

The chemical structure of 5-(1,3-dioxaindan-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one is particularly noteworthy. It consists of a penta-2,4-dienone backbone with a 1,3-dioxaindan and piperidine substituent. The presence of these functional groups imparts unique chemical and biological properties to the molecule. The 1,3-dioxaindan ring is known for its stability and ability to form hydrogen bonds, while the piperidine moiety contributes to the compound's lipophilicity and receptor binding affinity.

Synthesis of 5-(1,3-dioxaindan-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one has been extensively studied in recent years. One common approach involves the condensation of a suitable aldehyde with a piperidine derivative followed by cyclization to form the 1,3-dioxaindan ring. This method has been optimized to achieve high yields and purity levels, making it suitable for large-scale production. Additionally, alternative synthetic routes have been explored to enhance the efficiency and reduce the environmental impact of the process.

The biological activities of 5-(1,3-dioxaindan-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one have been the focus of numerous studies. Research has shown that this compound exhibits potent anti-inflammatory and anti-cancer properties. In vitro studies have demonstrated its ability to inhibit the production of pro-inflammatory cytokines such as TNF-alpha and IL-6. Furthermore, it has been found to induce apoptosis in cancer cells by modulating key signaling pathways such as PI3K/Akt and MAPK.

Clinical trials are currently underway to evaluate the safety and efficacy of 5-(1,3-dioxaindan-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one in treating various diseases. Preliminary results from phase I trials have shown promising outcomes with minimal adverse effects. These findings have paved the way for further clinical investigations and potential therapeutic applications.

In addition to its therapeutic potential, 5-(1,3-dioxaindan-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one has also been studied for its use in diagnostic imaging. Its unique structural features make it an excellent candidate for developing imaging agents that can target specific biomarkers in vivo. This application could significantly enhance the accuracy and sensitivity of diagnostic procedures.

The future prospects for 5-(1,3-dioxaindan-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-one are promising. Ongoing research is focused on optimizing its pharmacokinetic properties to improve bioavailability and reduce toxicity. Additionally, efforts are being made to develop novel formulations that can enhance its therapeutic efficacy and patient compliance.

In conclusion, 5-(1,3-dioxaindan-5-y l)-1-(piperidin - 1 - yl )pent a - 2 , 4 - dien - 1 - one (CAS No. 7780 - 20 - 3) is a multifaceted compound with significant potential in medicinal chemistry and pharmaceutical research. Its unique chemical structure and biological activities make it an attractive candidate for further development and clinical application. As research continues to advance, it is likely that this compound will play a crucial role in addressing unmet medical needs and improving patient outcomes.

7780-20-3 (5-(1,3-dioxaindan-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one) Related Products

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