Cas no 30489-44-2 ({2-methylimidazo1,2-apyridin-3-yl}methanol)

{2-Methylimidazo[1,2-a]pyridin-3-yl}methanol is a heterocyclic organic compound featuring a fused imidazopyridine core with a hydroxymethyl functional group at the 3-position. This structure imparts versatility in synthetic applications, particularly as an intermediate in pharmaceutical and agrochemical research. The hydroxymethyl group offers a reactive site for further derivatization, enabling the synthesis of more complex molecules. Its imidazopyridine scaffold is of interest due to its presence in bioactive compounds, making it valuable for drug discovery. The compound exhibits moderate stability under standard conditions, facilitating handling in laboratory settings. Its well-defined synthetic route ensures consistent purity, making it a reliable building block for medicinal chemistry and material science applications.
{2-methylimidazo1,2-apyridin-3-yl}methanol structure
30489-44-2 structure
Product Name:{2-methylimidazo1,2-apyridin-3-yl}methanol
CAS No:30489-44-2
MF:C9H10N2O
MW:162.188501834869
MDL:MFCD07368506
CID:303394
PubChem ID:7060539
Update Time:2025-11-06

{2-methylimidazo1,2-apyridin-3-yl}methanol Chemical and Physical Properties

Names and Identifiers

    • (2-Methylimidazo[1,2-a]pyridin-3-yl)methanol
    • (2-Methyl-lH-iMidazo[1,2-a]pyridin-3-yl)Methanol
    • {2-Methylimidazo[1,2-a]pyridin-3-yl}methanol
    • Imidazo[1,2-a]pyridine-3-methanol, 2-methyl-
    • 2-methylimidazo[1,2-a]pyridine-3-methanol
    • 3-(Hydroxymethyl)-2-methylimidazo[1,2-a]pyridine
    • 3-(hydroxymethyl)-2-methylimidazo<1,2-a>pyridine
    • 30489-44-2
    • SEKFTKBRYHPGEI-UHFFFAOYSA-N
    • DTXSID90427621
    • SCHEMBL859998
    • BG-0710
    • J-500870
    • AKOS000348756
    • CS-0450787
    • MFCD07368506
    • (2-Methylimidazo[1,2-a]pyridin-3-yl)methanol, AldrichCPR
    • AM803668
    • FT-0686335
    • AS-871/43475832
    • DB-010890
    • {2-methylimidazo1,2-apyridin-3-yl}methanol
    • MDL: MFCD07368506
    • Inchi: 1S/C9H10N2O/c1-7-8(6-12)11-5-3-2-4-9(11)10-7/h2-5,12H,6H2,1H3
    • InChI Key: SEKFTKBRYHPGEI-UHFFFAOYSA-N
    • SMILES: OCC1=C(C)N=C2C=CC=CN12

Computed Properties

  • Exact Mass: 162.07900
  • Monoisotopic Mass: 162.079312947g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 12
  • Rotatable Bond Count: 1
  • Complexity: 163
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 1.3
  • Topological Polar Surface Area: 37.5?2

Experimental Properties

  • Density: 1.22
  • Refractive Index: 1.622
  • PSA: 37.53000
  • LogP: 1.13500

{2-methylimidazo1,2-apyridin-3-yl}methanol Security Information

  • Hazard Statement: Irritant
  • Hazardous Material Identification: Xi

{2-methylimidazo1,2-apyridin-3-yl}methanol Customs Data

  • HS CODE:2933990090
  • Customs Data:

    China Customs Code:

    2933990090

    Overview:

    2933990090. Other heterocyclic compounds containing only nitrogen heteroatoms. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

    Declaration elements:

    Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date

    Summary:

    2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

{2-methylimidazo1,2-apyridin-3-yl}methanol Pricemore >>

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{2-methylimidazo1,2-apyridin-3-yl}methanol Related Literature

Additional information on {2-methylimidazo1,2-apyridin-3-yl}methanol

Comprehensive Overview of {2-methylimidazo[1,2-a]pyridin-3-yl}methanol (CAS No. 30489-44-2)

{2-methylimidazo[1,2-a]pyridin-3-yl}methanol (CAS No. 30489-44-2) is a heterocyclic organic compound that has garnered significant attention in pharmaceutical and agrochemical research due to its unique structural properties. The compound belongs to the imidazopyridine family, a class of molecules known for their diverse biological activities. Researchers and industry professionals frequently search for terms like "imidazopyridine derivatives", "pharmacological applications of 2-methylimidazopyridine", and "synthesis of CAS 30489-44-2", reflecting its relevance in drug discovery and development.

The molecular structure of {2-methylimidazo[1,2-a]pyridin-3-yl}methanol features a fused imidazole and pyridine ring system, with a hydroxymethyl group at the 3-position. This configuration contributes to its potential as a building block for bioactive molecules. Recent studies highlight its utility in designing kinase inhibitors and G-protein-coupled receptor (GPCR) modulators, aligning with trending topics such as "targeted cancer therapy" and "neurodegenerative disease treatment". The compound’s CAS No. 30489-44-2 is often referenced in patent literature, particularly in innovations related to central nervous system (CNS) drugs.

From a synthetic chemistry perspective, {2-methylimidazo[1,2-a]pyridin-3-yl}methanol can be prepared via multicomponent reactions or cyclization strategies, methods frequently explored in green chemistry initiatives. Queries like "sustainable synthesis of imidazopyridines" and "catalytic approaches for CAS 30489-44-2" underscore the demand for eco-friendly production techniques. Its solubility and stability profiles also make it a candidate for formulation optimization, a hot topic in drug delivery systems.

In agrochemical applications, derivatives of {2-methylimidazo[1,2-a]pyridin-3-yl}methanol have shown promise as plant growth regulators and pest control agents. This aligns with global interest in "sustainable agriculture" and "low-toxicity pesticides". The compound’s mechanism of action, possibly involving enzyme inhibition, is a subject of ongoing research, as indicated by searches for "imidazopyridine mode of action".

Analytical characterization of CAS No. 30489-44-2 typically involves NMR spectroscopy, mass spectrometry, and HPLC purity testing. These techniques address common questions like "how to analyze imidazopyridine compounds" and "quality control for CAS 30489-44-2". Regulatory compliance, especially concerning REACH and ICH guidelines, further emphasizes the need for precise documentation of its physicochemical properties.

In summary, {2-methylimidazo[1,2-a]pyridin-3-yl}methanol (CAS No. 30489-44-2) is a versatile scaffold with broad applications in medicinal chemistry and agrochemical innovation. Its integration into cutting-edge research on "precision medicine" and "green chemistry" ensures its continued relevance. Future studies may explore its role in bioconjugation or as a fluorescent probe, expanding its utility beyond traditional domains.

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