Cas no 30489-43-1 ({imidazo[1,2-a]pyridin-3-yl}methanol)

Technical Introduction: {Imidazo[1,2-a]pyridin-3-yl}methanol is a heterocyclic compound featuring a fused imidazole and pyridine ring system with a hydroxymethyl substituent at the 3-position. This structural motif imparts versatility in synthetic applications, particularly in medicinal chemistry and materials science. The compound serves as a valuable intermediate for the development of pharmacologically active molecules, including kinase inhibitors and antimicrobial agents, due to its ability to modulate electronic and steric properties. Its stability and reactivity under mild conditions make it suitable for diverse functionalization strategies. The hydroxymethyl group further enhances derivatization potential, enabling efficient conjugation or further synthetic elaboration. This compound is particularly useful in scaffold diversification for drug discovery programs.
{imidazo[1,2-a]pyridin-3-yl}methanol structure
30489-43-1 structure
Product Name:{imidazo[1,2-a]pyridin-3-yl}methanol
CAS No:30489-43-1
MF:C8H8N2O
MW:148.16192150116
MDL:MFCD09864457
CID:1016555
PubChem ID:13634586
Update Time:2025-10-28

{imidazo[1,2-a]pyridin-3-yl}methanol Chemical and Physical Properties

Names and Identifiers

    • Imidazo[1,2-a]pyridin-3-ylmethanol
    • 3-(hydroxymethyl)imidazo[1,2-a]-pyridine
    • 3-(Hydroxymethyl)imidazo[1,2-a]pyridine
    • 3-hydroxymethylimidazo[1,2-a]pyridine
    • AGN-PC-00NHHB
    • Ambcb4026329
    • ANW-59254
    • CTK4G5313
    • imidazo[1,2-a]pyridin-3-yl-methanol
    • imidazo[1,2-a]pyridin-3-ylmethanol(SALTDATA: FREE)
    • Imidazo[1,2-a]pyridine-3-methanol
    • Imidazo[1,2-a]pyridine-3-ylmethanol
    • SureCN9797098
    • {imidazo[1,2-a]pyridin-3-yl}methanol
    • EN300-103848
    • 3-hydroxymethyl imidazo[1,2-a]pyridine
    • 3-(Hydroxymethyl)imidazo[1 pound not2-a]pyridine
    • CS-0046995
    • DB-068301
    • SY024778
    • F2199-0350
    • AS-39573
    • DTXSID20545524
    • AM803667
    • Z1198235297
    • (Imidazo[1,2-a]pyridin-3-yl)methanol
    • SCHEMBL9797098
    • AKOS006281183
    • SB74616
    • MFCD09864457
    • 30489-43-1
    • SWAGAGZXOOYJDS-UHFFFAOYSA-N
    • MDL: MFCD09864457
    • Inchi: 1S/C8H8N2O/c11-6-7-5-9-8-3-1-2-4-10(7)8/h1-5,11H,6H2
    • InChI Key: SWAGAGZXOOYJDS-UHFFFAOYSA-N
    • SMILES: OCC1=CN=C2C=CC=CN12

Computed Properties

  • Exact Mass: 148.06400
  • Monoisotopic Mass: 148.063662883g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 11
  • Rotatable Bond Count: 1
  • Complexity: 140
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 0.9
  • Topological Polar Surface Area: 37.5?2

Experimental Properties

  • Density: 1.26
  • PSA: 37.53000
  • LogP: 0.82660

{imidazo[1,2-a]pyridin-3-yl}methanol Customs Data

  • HS CODE:2933990090
  • Customs Data:

    China Customs Code:

    2933990090

    Overview:

    2933990090. Other heterocyclic compounds containing only nitrogen heteroatoms. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

    Declaration elements:

    Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date

    Summary:

    2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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{imidazo[1,2-a]pyridin-3-yl}methanol Suppliers

Suzhou Senfeida Chemical Co., Ltd
Gold Member
Audited Supplier Audited Supplier
(CAS:30489-43-1)IMIDAZO[1,2-A]PYRIDIN-3-YLMETHANOL
Order Number:sfd640
Stock Status:in Stock
Quantity:200kg
Purity:99.9%
Pricing Information Last Updated:Friday, 19 July 2024 14:32
Price ($):discuss personally

Additional information on {imidazo[1,2-a]pyridin-3-yl}methanol

The Chemistry and Applications of {imidazo[1,2-a]pyridin-3-yl}methanol (CAS No. 30489-43-1)

{imidazo[1,2-a]pyridin-3-yl}methanol, also known by its CAS number 30489-43-1, is a heterocyclic compound with significant potential in various chemical and pharmaceutical applications. This compound belongs to the class of imidazopyridines, which are known for their unique electronic properties and structural versatility. The molecule consists of an imidazo[1,2-a]pyridine ring system attached to a methanol group, making it a valuable intermediate in organic synthesis.

The imidazo[1,2-a]pyridine core of this compound is a fused bicyclic structure comprising an imidazole ring fused to a pyridine ring. This arrangement imparts the molecule with aromaticity and conjugation, which are key factors in its reactivity and stability. The methanol group (-CH?OH) attached at the 3-position of the imidazo[1,2-a]pyridine ring introduces hydrophilic properties, enhancing its solubility in polar solvents. This makes {imidazo[1,2-a]pyridin-3-yl}methanol an ideal candidate for use in aqueous environments or as a precursor for more complex molecules.

Recent studies have highlighted the importance of {imidazo[1,2-a]pyridin-3-yl}methanol in drug discovery and development. Its structural flexibility allows for the incorporation of various functional groups, enabling the creation of bioactive compounds with potential therapeutic applications. For instance, researchers have explored its role as a building block for designing kinase inhibitors and other enzyme-targeting agents. The ability to modify the methanol group further expands its utility in medicinal chemistry.

In addition to its pharmaceutical applications, {imidazo[1,2-a]pyridin-3-yl}methanol has shown promise in materials science. Its aromaticity and conjugation make it a suitable candidate for use in organic electronics and optoelectronic devices. Recent advancements in this field have demonstrated that derivatives of this compound can exhibit desirable electronic properties, such as high electron mobility and photoluminescence efficiency. These characteristics position it as a potential material for use in light-emitting diodes (LEDs) and solar cells.

The synthesis of {imidazo[1,2-a]pyridin-3-yl}methanol typically involves multi-step organic reactions. One common approach involves the cyclization of appropriate precursors under acidic or basic conditions to form the imidazo[1,2-a]pyridine ring system. Subsequent functionalization steps allow for the introduction of the methanol group or other substituents. Recent research has focused on optimizing these synthetic routes to improve yield and selectivity while minimizing environmental impact.

From an environmental perspective, {imidazo[1,2-a]pyridin-3-yl}methanol has been studied for its biodegradability and toxicity profile. Initial findings suggest that it is not inherently hazardous under normal handling conditions; however, further studies are required to fully understand its environmental fate and potential risks.

In conclusion, {imidazo[1,2-a]pyridin-3-yl}methanol (CAS No. 30489-43-1) is a versatile compound with diverse applications across multiple disciplines. Its unique chemical structure and functional properties make it an invaluable tool in organic synthesis, drug discovery, and materials science. As research continues to uncover new possibilities for this compound, its role in advancing scientific innovation is expected to grow significantly.

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Suzhou Senfeida Chemical Co., Ltd
(CAS:30489-43-1)IMIDAZO[1,2-A]PYRIDIN-3-YLMETHANOL
sfd640
Purity:99.9%
Quantity:200kg
Price ($):Inquiry
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