Cas no 302962-49-8 (Dasatinib)
Dasatinib is a potent and selective inhibitor of BCR-ABL tyrosine kinase, effective in treating chronic myeloid leukemia (CML) and Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL). Its advantages lie in its high efficacy, even in resistant cases, as well as its ability to inhibit Src family kinases, contributing to reduced treatment resistance.
Dasatinib structure
Product Name:Dasatinib
CAS No:302962-49-8
MF:C22H26ClN7O2S
MW:488.005541324615
MDL:MFCD11046566
CID:67547
PubChem ID:3062316
Update Time:2025-09-04
Dasatinib Chemical and Physical Properties
Names and Identifiers
-
- DASATINIB
- Dasatinib & its intermediates (R&D)
- Dasatinib & its intermediates
- Dasatinib intermediate
- 5-Thiazolecarboxamide, N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-...
- 5-Thiazolecarboxamide, N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-
- Dasatinib (anhydrous)
- Dasatinib (BMS-354825,Sprycel?)
- Dasatinib anhydrous
- BMS354825
- BMS-354825
- Dasatinib Tablets
- SYR472
- Trelagliptin succinate
- N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl]amino]-1,3-thiazole-5-carboxamide
- BMS 354825
- MFCD11046566
- N-(2-chloro-6-methylphenyl)-2-(6-(4-(2-hydroxyethyl)piperazin-1-yl)-2-methylpyrimidin-4-ylamino)thiazole-5-carboxamide
- FT-0650671
- Dasatinib (BMS-354825)
- GTPL5678
- CHEBI:49375
- MLS006010904
- BDBM13216
- NCGC00181129-22
- NCGC00181129-12
- D5949
- BMS 35482513
- CAS-302962-49-8
- DTXCID2020979
- EX-A401
- BCPP000263
- NCGC00181129-03
- AKOS015902363
- NSC759877
- Q-101345
- 5-Thiazolecarboxamide, N-(2-chloro-6-methylphenyl)-2-((6-(4-(2-hydroxyethyl)-1-piperazinyl)-2-methyl-4-pyrimidinyl)amino)-
- HMS2043N05
- NSC-800087
- MLS003915609
- HMS3265C19
- CS-0100
- SR-00000000554-5
- BMS-354825-03
- HMS3244A06
- BMS 345825
- C22H26ClN7O2S
- NCGC00181129-14
- NCGC00181129-01
- DASATINIB [WHO-DD]
- BMS Dasatinib
- DTXCID50157977
- 302962-49-8 pound not863127-77-9
- N-(2-chloro-6-methyl-phenyl)-2-[[6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methyl-pyrimidin-4-yl]amino]thiazole-5-carboxamide
- BRD-K49328571-001-07-7
- DTXSID50235486
- EN300-123025
- DTXSID4040979
- HY-10181
- cid_3062316
- NS00001968
- anh. dasatinib
- 302962-49-8
- ZBNZXTGUTAYRHI-UHFFFAOYSA-N
- SCHEMBL8226
- N-(2-CHLORO-6-METHYLPHENYL)-2-({6-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]-2-METHYLPYRIMIDIN-4-YL}AMINO)-1,3-THIAZOLE-5-CARBOXAMIDE
- n-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamide
- HMS3244A05
- Q419940
- D-3307
- Pharmakon1600-01502275
- HMS3244B05
- HMS3654K05
- NSC-759877
- NCGC00181129-02
- NSC-732517
- AC-22749
- BCB03_000715
- NCGC00181129-07
- 5-Thiazolecarboxamide, monohydrate
- Tox21_112736
- dasatinib (anh.)
- HMS3744C11
- 2-(6-(4-(2-hydroxyethyl)piperazin-1-yl)-2-methylpyrimidin-4-ylamino)-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide
- DASATINIB [INN]
- DB01254
- NSC800087
- PA-3062316
- s1021
- CHEMBL1421
- CCG-264779
- UNII-RBZ1571X5H
- X78UG0A0RN
- UNII-X78UG0A0RN
- SMR002529551
- GS-6548
- Kinome_3650
- NSC 759877
- SR-00000000554
- N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl)]-2-methyl-4-pyrimidinyl]amino)]-1,3-thiazole-5-carboxamide
- NCGC00481571-01
- Tox21_112736_1
- AB01273956-02
- 1N1
- NCGC00181129-06
- HMS3265C20
- Sprycel
- MLS004774145
- Sprycel (Bristol Meyers)
- NCGC00181129-05
- AB01273956_03
- HMS3265D20
- Dasatinib [USAN:INN]
- L01XE06
- n-(2-chloro-6-methylphenyl)-2-((6-(4-(2-hydroxyethyl)piperazin-1-yl)-2-methylpyrimidin-4-yl)amino)-1,3-thiazole-5-carboxamide
- Dasatinib,BMS-354825
- BCP9000589
- BRD-K49328571-001-05-1
- CHEBI:70839
- NSC732517
- AR-270/43507994
- anhydrous dasatinib
- HMS3265D19
- Dasatinib (JAN/INN)
- DASATINIB [MI]
- AB01273956-01
- N-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl}amino)-1,3-thiazole-5-carboxamide
- Z1546610486
- BCP01797
- D03658
- SB17284
- SW208076-5
- AM20080877
- dasatinibum
- N-(2-chloro-6-methylphenyl)-2-((6-(4-(2-hydroxyethyl)piperazin-1-yl)-2-methylpyrimidin-4-yl)amino)thiazole-5-carboxamide
- BMS-354825 HYDRATE
- Dasatinib (BMS-354825)?
- BRD-K49328571-001-19-2
- BRD-K49328571-001-15-0
- SDCCGSBI-0061713.P004
- Dasatinib
-
- MDL： MFCD11046566
- Inchi： 1S/C22H26ClN7O2S/c1-14-4-3-5-16(23)20(14)28-21(32)17-13-24-22(33-17)27-18-12-19(26-15(2)25-18)30-8-6-29(7-9-30)10-11-31/h3-5,12-13,31H,6-11H2,1-2H3,(H,28,32)(H,24,25,26,27)
- InChI Key： ZBNZXTGUTAYRHI-UHFFFAOYSA-N
- SMILES： ClC1=CC=CC(C)=C1NC(C1=CN=C(NC2=CC(=NC(C)=N2)N2CCN(CCO)CC2)S1)=O
Computed Properties
- Exact Mass: 487.15600
- Monoisotopic Mass: 487.156
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 3
- Hydrogen Bond Acceptor Count: 9
- Heavy Atom Count: 33
- Rotatable Bond Count: 8
- Complexity: 642
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Surface Charge: 0
- Tautomer Count: 11
- XLogP3: 3.6
- Topological Polar Surface Area: 135A^2
Experimental Properties
- Color/Form: Powder
- Density: 1.4±0.1 g/cm3
- Melting Point: 275-286°C
- Boiling Point: No data available
- Flash Point: No data available
- Solubility: Soluble in DMSO (200 mg/mL), ethanol (very poorly ), and water (very poorly ).
- PSA: 134.75000
- LogP: 3.46240
Dasatinib Security Information
- Signal Word：Warning
- Hazard Statement： H315; H319; H335
- Warning Statement： P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501
- WGK Germany：3
- Safety Instruction： H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body
- Storage Condition：Powder -20°C 3 years ? 4°C 2 years In solvent -80°C 6 months ? -20°C 1 month
Dasatinib Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Fluorochem | 050286-1g |
Dasatinib |
302962-49-8 | 95+% | 1g |
￡42.00 | 2022-03-01 | |
| Fluorochem | 050286-5g |
Dasatinib |
302962-49-8 | 95+% | 5g |
￡145.00 | 2022-03-01 | |
| Fluorochem | 050286-10g |
Dasatinib |
302962-49-8 | 95+% | 10g |
￡272.00 | 2022-03-01 | |
| AstaTech | 62242-1/G |
DASATINIB |
302962-49-8 | 97% | 1/G |
$38 | 2022-06-01 | |
| AstaTech | 62242-5/G |
DASATINIB |
302962-49-8 | 97% | 5g |
$57 | 2023-09-16 | |
| AstaTech | 62242-10/G |
DASATINIB |
302962-49-8 | 97% | 10/G |
$250 | 2021-07-03 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | D125110-25mg |
Dasatinib |
302962-49-8 | ≥99% | 25mg |
￥41.90 | 2023-09-03 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | D125110-5g |
Dasatinib |
302962-49-8 | ≥99% | 5g |
￥712.90 | 2023-09-03 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | D125110-500mg |
Dasatinib |
302962-49-8 | ≥99% | 500mg |
￥144.90 | 2023-09-03 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | D125110-100mg |
Dasatinib |
302962-49-8 | ≥99% | 100mg |
￥51.90 | 2023-09-03 |
Dasatinib Suppliers
Suzhou Senfeida Chemical Co., Ltd
Gold Member
Audited Supplier
(CAS:302962-49-8)Dasatinib
Order Number:sfd10365
Stock Status:in Stock
Quantity:200kg
Purity:99.9%
Pricing Information Last Updated:Friday, 19 July 2024 14:35
Price ($):discuss personally
Email:[email protected]
Tiancheng Chemical (Jiangsu) Co., Ltd
Gold Member
Audited Supplier
(CAS:302962-49-8)Dasatinib
Order Number:LE736;LE5676927
Stock Status:in Stock
Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Friday, 20 June 2025 11:39
Price ($):discuss personally
Email:[email protected]
Dasatinib Related Literature
-
Benjamin J. Deadman,Mark D. Hopkin,Ian R. Baxendale,Steven V. Ley Org. Biomol. Chem. 2013 11 1766
-
Jianyi Wang,Qing Chen,Mian Wang,Cheng Zhong Phys. Chem. Chem. Phys. 2017 19 22444
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3. Gold nanoparticles and reduced graphene oxide-amplified label-free DNA biosensor for dasatinib detectionFahimeh Tahernejad-Javazmi,Mehdi Shabani-Nooshabadi,Hassan Karimi-Maleh New J. Chem. 2018 42 16378
-
Umar Ndagi,Maryam Abdullahi,Asmau N. Hamza,Mahmoud E. Soliman RSC Adv. 2020 10 145
-
Lingao Ruan,Di Su,Chang Shao,Jinjie Wang,Chaoqing Dong,Xiangyi Huang,Jicun Ren Analyst 2015 140 1207
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