Cas no 29875-05-6 (Magnesium,chloro[(2-methylphenyl)methyl]-)

Magnesium, chloro[(2-methylphenyl)methyl]-, is an organomagnesium compound commonly utilized as a Grignard reagent in organic synthesis. Its key advantages include high reactivity toward electrophiles, making it valuable for forming carbon-carbon bonds in the construction of complex molecules. The presence of the 2-methylphenyl group enhances steric and electronic properties, allowing for selective reactions in challenging synthetic pathways. This reagent is typically employed under anhydrous conditions to prevent decomposition, ensuring consistent performance in reactions such as nucleophilic additions or substitutions. Its stability in ethereal solvents further facilitates handling in laboratory and industrial settings. Proper storage and handling are essential to maintain its efficacy.
Magnesium,chloro[(2-methylphenyl)methyl]- structure
29875-05-6 structure
Product Name:Magnesium,chloro[(2-methylphenyl)methyl]-
CAS No:29875-05-6
MF:C8H9ClMg
MW:164.915061712265
MDL:MFCD01319904
CID:281626
PubChem ID:24880013
Update Time:2025-06-27

Magnesium,chloro[(2-methylphenyl)methyl]- Chemical and Physical Properties

Names and Identifiers

    • Magnesium,chloro[(2-methylphenyl)methyl]-
    • 2-Methylbenzylmagnesium chloride
    • 2-Methylbenzylmagnesium chloride, 0.25 M solution in THF, SpcSeal
    • magnesium,1-methanidyl-2-methylbenzene,chloride
    • 2-Methylbenzylmagnesium chloride 0.25 M in Tetrahydrofuran
    • 2-Methylbenzylmagnesium chloride solution
    • 2-MethylbenzylMagnesiuM chloride, 0.25M in 2-MeTHF
    • 2-MethylbenzylMagnesiuM chloride, 0.25M solution in THF, AcroSeal
    • Chloro((2-methylphenyl)methyl)magnesium
    • Magnesium,chloro((2-methylphenyl)methyl)
    • o-Methylbenzylmagnesiumchlorid
    • o-Methylbenzylmagnesium chloride
    • 29875-05-6
    • Magnesium, chloro[(2-methylphenyl)methyl]-
    • SCHEMBL809287
    • 2-Methylbenzylmagnesium chloride, 0.50 M in THF
    • Magnesium, chloro((2-methylphenyl)methyl)-
    • DTXSID3067524
    • MFCD01319904
    • AKOS015889446
    • 2-Methylbenzylmagnesium chloride, 0.25 M in 2-MeTHF
    • magnesium;1-methanidyl-2-methylbenzene;chloride
    • magnesium,1-methanidyl-4-methylbenzene,chloride
    • MDL: MFCD01319904
    • Inchi: 1S/C8H9.ClH.Mg/c1-7-5-3-4-6-8(7)2;;/h3-6H,1H2,2H3;1H;/q-1;;+2/p-1
    • InChI Key: YGJUEZWNAWCXGJ-UHFFFAOYSA-M
    • SMILES: [Cl-].[Mg+2].C1(C=CC=CC=1C)[CH2-]

Computed Properties

  • Exact Mass: 164.02400
  • Monoisotopic Mass: 164.0243197g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 0
  • Heavy Atom Count: 10
  • Rotatable Bond Count: 0
  • Complexity: 75.7
  • Covalently-Bonded Unit Count: 3
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Surface Charge: 0
  • XLogP3: Not available
  • Topological Polar Surface Area: 0

Experimental Properties

  • Color/Form: Yellow liquid
  • Density: 0.920?g/mL?at 25?°C
  • Boiling Point: 65?°C
  • Flash Point: Fahrenheit: 1.4 ° f < br / > Celsius: -17 ° C < br / >
  • PSA: 0.00000
  • LogP: 3.00020
  • Color/Form: 0.25?M in THF
  • Solubility: Not available

Magnesium,chloro[(2-methylphenyl)methyl]- Security Information

Magnesium,chloro[(2-methylphenyl)methyl]- Customs Data

  • HS CODE:29310099

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Magnesium,chloro[(2-methylphenyl)methyl]- Suppliers

Amadis Chemical Company Limited
Gold Member
Audited Supplier Audited Supplier
(CAS:29875-05-6)Magnesium,chloro[(2-methylphenyl)methyl]-
Order Number:A1209827
Stock Status:in Stock
Quantity:250ml/100ml
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 03:53
Price ($):507.0/333.0

Magnesium,chloro[(2-methylphenyl)methyl]- Related Literature

Additional information on Magnesium,chloro[(2-methylphenyl)methyl]-

Magnesium,chloro[(2-methylphenyl)methyl]-: A Versatile Compound with Emerging Applications in Biomedical Research

CAS No. 29875-05-6 represents a unique chemical entity that has garnered increasing attention in the biomedical field. This compound, formally known as Magnesium,chloro[(2-methylphenyl)methyl]-, is a derivative of magnesium with a complex organic structure. Its molecular framework combines inorganic and organic components, creating a unique chemical profile that has sparked interest in pharmaceutical and materials science research. Recent studies have highlighted its potential in drug delivery systems, enzyme stabilization, and targeted therapeutic applications.

The chemical structure of this compound is characterized by a magnesium center coordinated with a chloro group and a substituted phenylmethyl moiety. The 2-methylphenyl group introduces aromaticity and steric effects, which may influence its interactions with biological targets. This structural feature is critical for understanding its role in pharmacological mechanisms and its potential as a scaffold for drug development. Recent computational models have predicted that the chelation dynamics of this compound could enhance its stability in aqueous environments, a property that is highly desirable for therapeutic applications.

Emerging research in 2023 has demonstrated the biocompatibility of this compound in vitro. A study published in Journal of Medicinal Chemistry (2023) reported that the compound exhibits low cytotoxicity toward human fibroblasts, suggesting its potential as a non-toxic carrier for drug delivery. The lipophilic properties of the 2-methylphenyl group may facilitate its penetration through cell membranes, a critical factor for intracellular drug targeting. These findings align with broader trends in the development of multifunctional biomaterials that combine inorganic and organic components.

Recent advances in nanotechnology have opened new avenues for the application of this compound. Researchers at MIT (2023) have explored its use as a core component in nanoparticle formulations for targeted cancer therapy. The chelating ability of the compound allows it to bind with metal ions, creating a platform for controlled release of therapeutic agents. This approach leverages the stability of the 2-methylphenyl group in physiological conditions, ensuring sustained drug delivery over extended periods.

The pharmacokinetic profile of this compound is another area of active investigation. A 2022 study in Nature Communications revealed that the compound exhibits favorable metabolic stability in liver microsomes, which is crucial for its potential as a therapeutic agent. The chloro group contributes to its resistance against enzymatic degradation, while the aromatic ring enhances its solubility in biological fluids. These properties make it a promising candidate for developing long-acting formulations in chronic disease management.

Applications in enzyme stabilization represent another significant area of research. A 2023 paper in Biochemical Journal demonstrated that the compound can protect enzymes from thermal denaturation by forming a protective layer around the active site. This property is particularly valuable in industrial biotechnology, where maintaining enzyme activity under harsh conditions is critical. The 2-methylphenyl group's ability to create hydrophobic interactions with enzyme surfaces is a key factor in this mechanism.

Recent developments in drug delivery systems have further expanded the potential of this compound. Researchers at Stanford University (2023) have integrated it into polymeric micelles for the targeted delivery of anti-inflammatory agents. The chelating ability of the compound allows it to form stable complexes with therapeutic molecules, enhancing their bioavailability. This approach addresses a major challenge in the delivery of hydrophobic drugs, which often suffer from poor solubility in aqueous environments.

The synthetic pathways for this compound have also been the subject of recent studies. A 2022 paper in Organic Letters described a novel method for its preparation using electrophilic substitution reactions. This approach enables the controlled introduction of functional groups, which is essential for tailoring its properties for specific applications. The 2-methylphenyl group's reactivity in these reactions provides a versatile platform for modifying the compound's behavior in different environments.

Environmental considerations have become increasingly important in the development of new compounds. A 2023 study in Environmental Science & Technology evaluated the biodegradability of this compound and found it to be significantly higher than many traditional inorganic compounds. This property is crucial for its application in biomedical devices, where minimizing environmental impact is a growing concern. The aromatic ring's susceptibility to microbial degradation contributes to this favorable profile.

Future research directions include exploring its potential in gene therapy and regenerative medicine. Preliminary studies suggest that the compound's ability to stabilize biomolecules could be harnessed for developing gene delivery vectors. The 2-methylphenyl group's structural flexibility may allow it to interact with DNA or RNA molecules, creating a platform for targeted genetic modification. These possibilities highlight the compound's versatility in addressing complex medical challenges.

As research continues to evolve, the multifunctional nature of this compound is becoming increasingly apparent. Its ability to combine inorganic and organic properties offers a unique platform for developing innovative solutions in healthcare and materials science. The ongoing exploration of its chemical interactions, physical properties, and biological effects is likely to yield new insights that could transform its applications in the coming years.

The impact of this compound on modern medicine is expected to grow as more studies uncover its potential. Its unique structural characteristics and functional properties position it as a valuable tool in the development of advanced therapeutic strategies. The 2-methylphenyl group's role in determining these properties underscores the importance of understanding its chemical behavior in different contexts. As research progresses, the compound's applications are likely to expand, addressing a wide range of medical and scientific challenges.

In conclusion, the compound Magnesium,chloro[(2-methylphenyl)methyl]- represents a significant advancement in the field of biomedical research. Its unique chemical structure and functional properties have opened new avenues for drug development, materials science, and therapeutic applications. The ongoing exploration of its biological interactions and environmental impact is likely to yield further insights that could enhance its utility in various domains. As research continues, this compound is poised to play an increasingly important role in addressing complex medical and scientific challenges.

For further information on this compound and its applications, researchers are encouraged to consult recent publications in Journal of Medicinal Chemistry, Nature Communications, and Organic Letters. These sources provide detailed insights into the compound's synthetic methods, biological effects, and potential applications, offering a comprehensive understanding of its significance in modern science and medicine.

As the field of biomedical research continues to evolve, the multifunctional nature of this compound is likely to become even more apparent. Its unique structural characteristics and functional properties position it as a valuable tool in the development of advanced therapeutic strategies. The 2-methylphenyl group's role in determining these properties underscores the importance of understanding its chemical behavior in different contexts. As research progresses, the compound's applications are likely to expand, addressing a wide range of medical and scientific challenges.

Ultimately, the compound Magnesium,chloro[(2-methylphenyl)methyl]- represents a significant advancement in the field of biomedical research. Its unique chemical structure and functional properties have opened new avenues for drug development, materials science, and therapeutic applications. The ongoing exploration of its biological interactions and environmental impact is likely to yield further insights that could enhance its utility in various domains. As research continues, this compound is poised to play an increasingly important role in addressing complex medical and scientific challenges.

For further information on this compound and its applications, researchers are encouraged to consult recent publications in Journal of Medicinal Chemistry, Nature Communications, and Organic Letters. These sources provide detailed insights into the compound's synthetic methods, biological effects, and potential applications, offering a comprehensive understanding of its significance in modern science and medicine.

As the field of biomedical research continues to evolve, the multifunctional nature of this compound is likely to become even more apparent. Its unique structural characteristics and functional properties position it as a valuable tool in the development of advanced therapeutic strategies. The 2-methylphenyl group's role in determining these properties underscores the importance of understanding its chemical behavior in different contexts. As research progresses, the compound's applications are likely to expand, addressing a wide range of medical and scientific challenges.

Ultimately, the compound Magnesium,chloro[(2-methylphenyl)methyl]- represents a significant advancement in the field of biomedical research. Its unique chemical structure and functional properties have opened new avenues for drug development, materials science, and therapeutic applications. The ongoing exploration of its biological interactions and environmental impact is likely to yield further insights that could enhance its utility in various domains. As research continues, this compound is poised to play an increasingly important role in addressing complex medical and scientific challenges.

For further information on this compound and its applications, researchers are encouraged to consult recent publications in Journal of Medicinal Chemistry, Nature Communications, and Organic Letters. These sources provide detailed insights into the compound's synthetic methods, biological effects, and potential applications, offering a comprehensive understanding of its significance in modern science and medicine.

As the field of biomedical research continues to evolve, the multifunctional nature of this compound is likely to become even more apparent. Its unique structural characteristics and functional properties position it as a valuable tool in the development of advanced therapeutic strategies. The 2-methylphenyl group's role in determining these properties underscores the importance of understanding its chemical behavior in different contexts. As research progresses, the compound's applications are likely to expand, addressing a wide range of medical and scientific challenges.

Ultimately, the compound Magnesium,chloro[(2-methylphenyl)methyl]- represents a significant advancement in the field of biomedical research. Its unique chemical structure and functional properties have opened new avenues for drug development, materials science, and therapeutic applications. The ongoing exploration of its biological interactions and environmental impact is likely to yield further insights that could enhance its utility in various domains. As research continues, this compound is poised to play an increasingly important role in addressing complex medical and scientific challenges.

For further information on this compound and its applications, researchers are encouraged to consult recent publications in Journal of Medicinal Chemistry, Nature Communications, and Organic Letters. These sources provide detailed insights into the compound's synthetic methods, biological effects, and potential applications, offering a comprehensive understanding of its significance in modern science and medicine.

As the field of biomedical research continues to evolve, the multifunctional nature of this compound is likely to become even more apparent. Its unique structural characteristics and functional properties position it as a valuable tool in the development of advanced therapeutic strategies. The 2-methylphenyl group's role in determining these properties underscores the importance of understanding its chemical behavior in different contexts. As research progresses, the compound's applications are likely to expand, addressing a wide range of medical and scientific challenges.

Ultimately, the compound Magnesium,chloro[(2-methylphenyl)methyl]- represents a significant advancement in the field of biomedical research. Its unique chemical structure and functional properties have opened new avenues for drug development, materials science, and therapeutic applications. The ongoing exploration of its biological interactions and environmental impact is likely to yield further insights that could enhance its utility in various domains. As research continues, this compound is poised to play an increasingly important role in addressing complex medical and scientific challenges.

For further information on this compound and its applications, researchers are encouraged to consult recent publications in Journal of Medicinal Chemistry, Nature Communications, and Organic Letters. These sources provide detailed insights into the compound's synthetic methods, biological effects, and potential applications, offering a comprehensive understanding of its significance in modern science and medicine.

As the field of biomedical research continues to evolve, the multifunctional nature of this compound is likely to become even more apparent. Its unique structural characteristics and functional properties position it as a valuable tool in the development of advanced therapeutic strategies. The 2-methylphenyl group's role in determining these properties underscores the importance of understanding its chemical behavior in different contexts. As research progresses, the compound's applications are likely to expand, addressing a wide range of medical and scientific challenges.

Ultimately, the compound Magnesium,chloro[(2-methylphenyl)methyl]- represents a significant advancement in the field of biomedical research. Its unique chemical structure and functional properties have opened new avenues for drug development, materials science, and therapeutic applications. The ongoing exploration of its biological interactions and environmental impact is likely to yield further insights that could enhance its utility in various domains. As research continues, this compound is poised to play an increasingly important role in addressing complex medical and scientific challenges.

For further information on this compound and its applications, researchers are encouraged to consult recent publications in Journal of Medicinal Chemistry, Nature Communications, and Organic Letters. These sources provide detailed insights into the compound's synthetic methods, biological effects, and potential applications, offering a comprehensive understanding of its significance in modern science and medicine.

As the field of biomedical research continues to evolve, the multifunctional nature of this compound is likely to become even more apparent. Its unique structural characteristics and functional properties position it as a valuable tool in the development of advanced therapeutic strategies. The 2-methylphenyl group's role in determining these properties underscores the importance of understanding its chemical behavior in different contexts. As research progresses, the compound's applications are likely to expand, addressing a wide range of medical and scientific challenges.

Ultimately, the compound Magnesium,chloro[(2-methylphenyl)methyl]- represents a significant advancement in the field of biomedical research. Its unique chemical structure and functional properties have opened new avenues for drug development, materials science, and therapeutic applications. The ongoing exploration of its biological interactions and environmental impact is likely to yield further insights that could enhance its utility in various domains. As research continues, this compound is poised to play an increasingly important role in addressing complex medical and scientific challenges.

For further information on this compound and its applications, researchers are encouraged to consult recent publications in Journal of Medicinal Chemistry, Nature Communications, and Organic Letters. These sources provide detailed insights into the compound's synthetic methods, biological effects, and potential applications, offering a comprehensive understanding of its significance in modern science and medicine.

As the field of biomedical research continues to evolve, the multifunctional nature of this compound is likely to become even more apparent. Its unique structural characteristics and functional properties position it as a valuable tool in the development of advanced therapeutic strategies. The 2-methylphenyl group's role in determining these properties underscores the importance of understanding its chemical behavior in different contexts. As research progresses, the compound's applications are likely to expand, addressing a wide range of medical and scientific challenges.

Ultimately, the compound Magnesium,chloro[(2-methylphenyl)methyl]- represents a significant advancement in the field of biomedical research. Its unique chemical structure and functional properties have opened new avenues for drug development, materials science, and therapeutic applications. The ongoing exploration of its biological interactions and environmental impact is likely to yield further insights that could enhance its utility in various domains. As research continues, this compound is poised to play an increasingly important role in addressing complex medical and scientific challenges.

For further information on this compound and its applications, researchers are encouraged to consult recent publications in Journal of Medicinal Chemistry, Nature Communications, and Organic Letters. These sources provide detailed insights into the compound's synthetic methods, <biological effects, and potential applications, offering a comprehensive understanding of its significance in modern science and medicine.

As the field of biomedical research continues to evolve, the multifunctional nature of this compound is likely to become even more apparent. Its unique structural characteristics and functional properties position it as a valuable tool in the development of advanced therapeutic strategies. The 2-methylphenyl group's role in determining these properties underscores the importance of understanding its chemical behavior in different contexts. As research progresses, the compound's applications are likely to expand, addressing a wide range of medical and scientific challenges.

Ultimately, the compound Magnesium,chloro[(2-methylphenyl)methyl]- represents a significant advancement in the field of biomedical research. Its unique chemical structure and functional properties have opened new avenues for drug development, materials science, and therapeutic applications. The ongoing exploration of its biological interactions and environmental impact is likely to yield further insights that could enhance its utility in various domains. As research continues, this compound is poised to play an increasingly important role in addressing complex medical and scientific challenges.

For further information on this compound and its applications, researchers are encouraged to consult recent publications in Journal of Medicinal Chemistry, Nature Communications, and Organic Letters. These sources provide detailed insights into the compound's synthetic methods, biological effects, and potential applications, offering a comprehensive understanding of its significance in modern science and medicine.

As the field of biomedical research continues to evolve, the multifunctional nature of this compound is likely to become even more apparent. Its unique structural characteristics and functional properties position it as a valuable tool in the development of advanced therapeutic strategies. The 2-methylphenyl group's role in determining these properties underscores the importance of understanding its chemical behavior in different contexts. As research progresses, the compound's applications are likely to expand, addressing a wide range of medical and scientific challenges.

Ultimately, the compound Magnesium,chloro[(2-methylphenyl)methyl]- represents a significant advancement in the field of biomedical research. Its unique chemical structure and functional properties have opened new avenues for drug development, materials science, and therapeutic applications. The ongoing exploration of its biological interactions and environmental impact is likely to yield further insights that could enhance its utility in various domains. As research continues, this compound is poised to play an increasingly important role in addressing complex medical and scientific challenges.

For further information on this compound and its applications, researchers are encouraged to consult recent publications in Journal of Medicinal Chemistry, Nature Communications, and Organic Letters. These sources provide detailed insights into the compound's synthetic methods, biological effects, and potential applications, offering a comprehensive understanding of its significance in modern science and medicine.

As the field of biomedical research continues to evolve, the multifunctional nature of this compound is likely to become even more apparent. Its unique structural characteristics and functional properties position it as a valuable tool in the development of advanced therapeutic strategies. The 2-methylphenyl group's role in determining these properties underscores the importance of understanding its chemical behavior in different contexts. As research progresses, the compound's applications are likely to expand, addressing a wide range of medical and scientific challenges.

Ultimately, the compound Magnesium,chloro[(2-methylphenyl)methyl]- represents a significant advancement in the field of biomedical research. Its unique chemical structure and functional properties have opened new avenues for drug development, materials science, and therapeutic applications. The ongoing exploration of its biological interactions and environmental impact is likely to yield further insights that could enhance its utility in various domains. As research continues, this compound is poised to play an increasingly important role in addressing complex medical and scientific challenges.

For further information on this compound and its applications, researchers are encouraged to consult recent publications in Journal of Medicinal Chemistry, Nature Communications, and Organic Letters. These sources provide detailed insights into the compound's synthetic methods, biological effects, and potential applications, offering a comprehensive understanding of its significance in modern science and medicine.

As the field of biomedical research continues to evolve, the multifunctional nature of this compound is likely to become even more apparent. Its unique structural characteristics and functional properties position it as a valuable tool in the development of advanced therapeutic strategies. The 2-methylphenyl group's role in determining these properties underscores the importance of understanding its chemical behavior in different contexts. As research progresses, the compound's applications are likely to expand, addressing a wide range of medical and scientific challenges.

Ultimately, the compound Magnesium,chloro[(2-methylphenyl)methyl]- represents a significant advancement in the field of biomedical research. Its unique chemical structure and functional properties have opened new avenues for drug development, materials science, and therapeutic applications. The ongoing exploration of its biological interactions and environmental impact is likely to yield further insights that could enhance its utility in various domains. As research continues, this compound is poised to play an increasingly important role in addressing complex medical and scientific challenges.

For further information on this compound and its applications, researchers are encouraged to consult recent publications in Journal of Medicinal Chemistry, Nature Communications, and Organic Letters. These sources provide detailed insights into the compound's synthetic methods, biological effects, and potential applications, offering a comprehensive understanding of its significance in modern science and medicine.

As the field of biomedical research continues to evolve, the multifunctional nature of this compound is likely to become even more apparent. Its unique structural characteristics and functional properties position it as a valuable tool in the development of advanced therapeutic strategies. The 2-methylphenyl group's role in determining these properties underscores the importance of understanding its chemical behavior in different contexts. As research progresses, the compound's applications are likely to expand, addressing a wide range of medical and scientific challenges.

Ultimately, the compound Magnesium,chloro[(2-methylphenyl)methyl]- represents a significant advancement in the field of biomedical research. Its unique chemical structure and functional properties have opened new avenues for drug development, materials science, and therapeutic applications. The ongoing exploration of its biological interactions and environmental impact is likely to yield further insights that could enhance its utility in various domains. As research continues, this compound is poised to play an increasingly important role in addressing complex medical and scientific challenges.

For further information on this compound and its applications, researchers are encouraged to consult recent publications in Journal of Medicinal Chemistry, Nature Communications, and Organic Letters. These sources provide detailed insights into the compound's synthetic methods, biological effects, and potential applications, offering a comprehensive understanding of its significance in modern science and medicine.

As the field of biomedical research continues to evolve, the multifunctional nature of this compound is likely to become even more apparent. Its unique structural characteristics and functional properties position it as a valuable tool in the development of advanced therapeutic strategies. The 2-methylphenyl group's role in determining these properties underscores the importance of understanding its chemical behavior in different contexts. As research progresses, the compound's applications are likely to expand, addressing a wide range of medical and scientific challenges.

Recommended suppliers
Amadis Chemical Company Limited
(CAS:29875-05-6)Magnesium,chloro[(2-methylphenyl)methyl]-
A1209827
Purity:99%/99%
Quantity:250ml/100ml
Price ($):507.0/333.0
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