- A mixed anhydride approach to the preparation of sulfinate esters and allylic sulfones: Trimethylacetic p-toluenesulfinic anhydrideJacobsen, Eric; Chavda, Mihir K.; Zikpi, Kokou M.; Waggoner, Stephanie L.; Passini, Daniel J.; et al, Tetrahedron Letters, 2017, 58(31), 3073-3077
Cas no 2943-42-2 (p-Tolyl p-toluenethiosulfonate)
p-Tolyl p-toluenethiosulfonate is an organosulfur compound characterized by its thiosulfonate functional group (–S(O)?–S–). This reagent is primarily utilized in organic synthesis as a sulfenylating or sulfonylating agent, enabling the introduction of p-tolylthio or p-toluenesulfonyl groups into target molecules. Its stability and selective reactivity make it valuable for constructing sulfur-containing frameworks, including thioethers and sulfonamides. The compound’s well-defined structure ensures consistent performance in controlled transformations, particularly in pharmaceutical and materials science applications. Handling requires standard precautions for sulfur-based reagents, but its crystalline form facilitates precise measurement. Its utility in cross-coupling and functional group interconversion underscores its importance in synthetic chemistry.
2943-42-2 structure
Product Name:p-Tolyl p-toluenethiosulfonate
CAS No:2943-42-2
MF:C14H14O2S2
MW:278.389761447906
MDL:MFCD00092126
CID:260732
PubChem ID:354333312
Update Time:2025-10-29
p-Tolyl p-toluenethiosulfonate Chemical and Physical Properties
Names and Identifiers
-
- Benzenesulfonothioicacid, 4-methyl-, S-(4-methylphenyl) ester
- S-p-Tolyl p-Toluenesulfonothioate
- S-p-Tolyl p-toluenethiolsulfonate
- 4-methylphenyl-4-methyl-benzenethiosulfonate
- p-TolSO2S-p-Tol
- p-Toluenesulfonothioic acid S-p-tolyl ester
- p-Toluenethiosulfonic acid S-p-tolyl ester
- p-Tolyl p-toluenethiolsulfonate
- p-Tolyl p-toluenethiosulfonate
- S-p-tolyl 4-methylbenzenesulfonothioate
- toluene-4-thiosulfonic acid S-p-tolyl ester
- NSC 86030
- S-(4-Methylphenyl) 4-methylbenzenesulfonothioate
- Benzenesulfonothioic acid, 4-methyl-, S-(4-methylphenyl) ester
- NSC86030
- p-Tolylthio p-tolyl sulfone
- p-Toluenesulfonic acid, thio-, S-p-tolyl ester
- NCIOpen2_004951
- p-Tolyl-p-toluenethiolsulfonate
- T3173
- S-(4-Methylphenyl) 4-methylbenzene-1-sulfonothioate
- CS-0320538
- SCHEMBL3917191
- 2943-42-2
- Benzenesulfonothioic acid, S-(4-methylphenyl) ester
- NSC-86030
- HSAROCRPZOYKGS-UHFFFAOYSA-N
- 1-methyl-4-(4-methylphenyl)sulfonylsulfanylbenzene
- CHEMBL120235
- MFCD00092126
- T72243
- DTXSID90951951
- AS-71356
- 1-METHYL-4-[(4-METHYLBENZENESULFONYL)SULFANYL]BENZENE
- Benzenethiosulfonic acid, 4-methyl-, S-(4-methylphenyl) ester
- 1-methyl-4-(p-tolylsulfonylsulfanyl)benzene
- AE-641/00404034
- S-(4-Methylphenyl) 4-methylbenzenesulfonothioate #
- p-Toluenesulfonic acid, S-p-tolyl ester
- AKOS024338409
- S-(p-tolyl) 4-methylbenzenesulfonothioate
- S-(p-tolyl) p-toluenethiosulfonate
- S-p-Tolyl4-methylbenzenesulfonothioate
-
- MDL： MFCD00092126
- Inchi： 1S/C14H14O2S2/c1-11-3-7-13(8-4-11)17-18(15,16)14-9-5-12(2)6-10-14/h3-10H,1-2H3
- InChI Key： HSAROCRPZOYKGS-UHFFFAOYSA-N
- SMILES： S(C1C=CC(C)=CC=1)(=O)(=O)SC1C=CC(C)=CC=1
Computed Properties
- Exact Mass: 278.04400
- Monoisotopic Mass: 278.044
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 3
- Heavy Atom Count: 18
- Rotatable Bond Count: 3
- Complexity: 343
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 67.8
- XLogP3: 3.9
Experimental Properties
- Density: 1.28
- Melting Point: 72.0 to 76.0 deg-C
- Boiling Point: 432.5±48.0 °C at 760 mmHg
- Flash Point: 215.4±29.6 °C
- Refractive Index: 1.637
- PSA: 67.82000
- LogP: 4.86520
- λmax: 236(EtOH)(lit.)
- Vapor Pressure: 0.0±1.0 mmHg at 25°C
p-Tolyl p-toluenethiosulfonate Security Information
- Signal Word：warning
- Hazard Statement： H303 may be harmful by ingestion +h313 may be harmful by skin contact +h1106 may be harmful by inhalation
-
Warning Statement：
P264 wash thoroughly after treatment
p280 wear protective gloves / wear protective clothing / wear protective eye masks / wear protective masks
p305 if in eyes
p351 rinse carefully with water for a few minutes
p338 remove contact lenses (if any) and easy to operate, continue rinsing
p337 if eye irritation persists
p1086 get medical advice / care - Safety Instruction： H303 may be harmful by ingestion +h313 may be harmful by skin contact +h1106 may be harmful by inhalation
- Storage Condition：4° CStore…,-4℃Store…Better
p-Tolyl p-toluenethiosulfonate Customs Data
- HS CODE：2930909090
- Customs Data：
China Customs Code:
2930909090Overview:
2930909090. Other organic sulfur compounds. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:30.0%
Declaration elements:
Product Name, component content, use to
Summary:
2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
p-Tolyl p-toluenethiosulfonate Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | S161289-1G |
p-Tolyl p-toluenethiosulfonate |
2943-42-2 | >98.0%(HPLC) | 1g |
￥653.90 | 2023-09-01 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | S161289-200mg |
p-Tolyl p-toluenethiosulfonate |
2943-42-2 | >98.0%(HPLC) | 200mg |
￥212.90 | 2023-09-01 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | S161289-5G |
p-Tolyl p-toluenethiosulfonate |
2943-42-2 | >98.0%(HPLC) | 5g |
￥2958.90 | 2023-09-01 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | T3173-5g |
p-Tolyl p-toluenethiosulfonate |
2943-42-2 | 98.0%(LC) | 5g |
￥3510.0 | 2022-06-10 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | T3173-1g |
p-Tolyl p-toluenethiosulfonate |
2943-42-2 | 98.0%(LC) | 1g |
￥915.0 | 2022-06-10 | |
| TI XI AI ( SHANG HAI ) HUA CHENG GONG YE FA ZHAN Co., Ltd. | T3173-1G |
S-p-Tolyl p-Toluenesulfonothioate |
2943-42-2 | >98.0%(HPLC) | 1g |
￥650.00 | 2024-04-16 | |
| TI XI AI ( SHANG HAI ) HUA CHENG GONG YE FA ZHAN Co., Ltd. | T3173-5G |
S-p-Tolyl p-Toluenesulfonothioate |
2943-42-2 | >98.0%(HPLC) | 5g |
￥2950.00 | 2024-04-16 | |
| eNovation Chemicals LLC | D758212-1g |
Benzenesulfonothioic acid, 4-methyl-, S-(4-methylphenyl) ester |
2943-42-2 | 98.0% | 1g |
$150 | 2024-06-07 | |
| eNovation Chemicals LLC | D758212-5g |
Benzenesulfonothioic acid, 4-methyl-, S-(4-methylphenyl) ester |
2943-42-2 | 98.0% | 5g |
$455 | 2024-06-07 | |
| SHANG HAI HAO HONG Biomedical Technology Co., Ltd. | 1391208-1g |
S-(p-tolyl) 4-methylbenzenesulfonothioate |
2943-42-2 | 95+% | 1g |
￥1310.00 | 2024-08-03 |
p-Tolyl p-toluenethiosulfonate Production Method
Production Method 1
Reaction Conditions
1.1 Reagents: Triethylamine ; overnight, rt
Reference
p-Tolyl p-toluenethiosulfonate Raw materials
p-Tolyl p-toluenethiosulfonate Preparation Products
p-Tolyl p-toluenethiosulfonate Related Literature
-
Suguru Yoshida,Yasuyuki Sugimura,Yuki Hazama,Yoshitake Nishiyama,Takahisa Yano,Shigeomi Shimizu,Takamitsu Hosoya Chem. Commun. 2015 51 16613
-
2. Rhodium-catalyzed odorless synthesis of diaryl sulfides from borylarenes and S-aryl thiosulfonatesKazuya Kanemoto,Yasuyuki Sugimura,Shigeomi Shimizu,Suguru Yoshida,Takamitsu Hosoya Chem. Commun. 2017 53 10640
2943-42-2 (p-Tolyl p-toluenethiosulfonate) Related Products
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- 3541-14-8(S-Phenyl 4-methylbenzenesulfonothioate)
- 4973-66-4(1-methyl-4-(methylsulfanyl)sulfonylbenzene)
- 139131-40-1(Benzenesulfonothioic acid, 4-methyl-, S-ethenyl ester)
- 17041-81-5(Benzenesulfonothioic acid, S-(4-methylphenyl) ester)
- 28519-30-4(Benzenesulfonothioic acid, 4-methyl-, S-ethyl ester)
- 7559-49-1(Methanesulfonothioic acid, S-(4-methylphenyl) ester)
- 1212-08-4(S-Phenyl Benzenethiosulfonate)
- 10409-07-1(Disulfone,bis(4-methylphenyl) (9CI))
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