Cas no 287172-63-8 (2,4,5-Trifluorobenzenesulfonamide)

2,4,5-Trifluorobenzenesulfonamide is a fluorinated benzenesulfonamide derivative characterized by its trifluorinated aromatic ring structure. This compound serves as a versatile intermediate in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals. The presence of fluorine atoms enhances its electron-withdrawing properties, improving reactivity in nucleophilic substitution and cross-coupling reactions. Its sulfonamide moiety offers functionalization potential for further derivatization. The compound exhibits stability under standard conditions, facilitating handling and storage. Its structural features make it valuable in the design of bioactive molecules, where fluorination often improves metabolic stability and binding affinity. Suitable for use in controlled environments, it requires standard precautions for sulfonamide handling.

2,4,5-Trifluorobenzenesulfonamide structure

287172-63-8 structure

Product Name:2,4,5-Trifluorobenzenesulfonamide

CAS No:287172-63-8

MF:C₆H₄F₃NO₂S

MW:211.161670684814

MDL:MFCD01569462

CID:852485

PubChem ID:2776974

Update Time:2025-06-08

2,4,5-Trifluorobenzenesulfonamide Chemical and Physical Properties

Names and Identifiers

- 2,4,5-Trifluorobenzenesulfonamide
- Benzenesulfonamide, 2,4,5-trifluoro-
- 2,4,5-trifluorobenzenesulphonamide
- 2,4,5-trifluorobenzesulfonamide
- SBB094459
- SC5046
- 2,4,5-trifluorobenzene-1-sulfonamide
- AK112839
- ST51041470
- ST24038578
- DTXSID00380314
- AKOS008160965
- SB78704
- 287172-63-8
- CS-0179141
- SCHEMBL1137624
- MFCD01569462
- DS-6047
- EN300-271044
- MDL： MFCD01569462
- Inchi： 1S/C6H4F3NO2S/c7-3-1-5(9)6(2-4(3)8)13(10,11)12/h1-2H,(H2,10,11,12)
- InChI Key： DJZNADBWJLAUPG-UHFFFAOYSA-N
- SMILES： S(C1C=C(C(=CC=1F)F)F)(N)(=O)=O

Computed Properties

Exact Mass: 210.99152
Monoisotopic Mass: 210.99148403g/mol
Isotope Atom Count: 0
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 6
Heavy Atom Count: 13
Rotatable Bond Count: 1
Complexity: 276
Covalently-Bonded Unit Count: 1
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count : 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Topological Polar Surface Area: 68.5
XLogP3: 0.8

Experimental Properties

Density: 1.611±0.06 g/cm3 (20 oC 760 Torr),
Boiling Point: 305.8°C at 760 mmHg
Solubility: Very slightly soluble (0.23 g/l) (25 o C),
PSA: 60.16

2,4,5-Trifluorobenzenesulfonamide Security Information

Signal Word：Warning
Hazard Statement： H302+H312+H332-H315-H319-H335
Warning Statement： P261-P280-P305+P351+P338
Hazardous Material Identification：
Storage Condition：Sealed in dry,Room Temperature

2,4,5-Trifluorobenzenesulfonamide Pricemore >>

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