• 1. Acetylcholinesterase amperometric detection system based on a cobalt(II) tetraphenylporphyrin-modified electrode
  Analyst, 1996,121, 1123-1126
• 2. An aquatic host–guest complex between a supramolecular G-quadruplex and the anticancer drug doxorubicin?
  José M. Rivera,Mariana Martín-Hidalgo,Jean C. Rivera-Ríos Org. Biomol. Chem., 2012,10, 7562-7565
• 3. An atmosphere and light tuned highly diastereoselective synthesis of cyclobuta/penta[b]indoles from aniline-tethered alkylidenecyclopropanes with alkynes?
  Bo Cao,Yin Wei Chem. Commun., 2018,54, 2870-2873
• 4. An integrated digital microfluidic chip for multiplexed proteomic sample preparation and analysis by MALDI-MS?
  Hyejin Moon,Aaron R. Wheeler,Robin L. Garrell,Chang-Jin “CJ” Kim Lab Chip, 2006,6, 1213-1219
• 5. An air-stable organometallic polymer containing titanafluorene moieties obtained by the Sonogashira–Hagihara cross-coupling polycondensation?
  Alvin Tanudjaja,Shinsuke Inagi,Fusao Kitamura,Toshikazu Takata,Ikuyoshi Tomita Dalton Trans., 2021,50, 3037-3043

• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Benzoic acids
• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Benzoic acids and derivatives Benzoic acids

Comprehensive Guide to 3-(2-Methyl-1,3-thiazol-4-yl)benzoic Acid (CAS No. 28077-41-0): Properties, Applications, and Market Insights

3-(2-Methyl-1,3-thiazol-4-yl)benzoic Acid (CAS No. 28077-41-0) is a specialized organic compound that has garnered significant attention in pharmaceutical and agrochemical research. This thiazole-containing benzoic acid derivative exhibits unique structural features that make it valuable for various applications. With the increasing demand for heterocyclic compounds in drug discovery, understanding this molecule's properties and potential uses becomes crucial for researchers and industry professionals.

The molecular structure of 3-(2-Methyl-1,3-thiazol-4-yl)benzoic Acid combines a benzoic acid moiety with a 2-methylthiazole ring, creating interesting electronic and steric properties. This combination is particularly relevant in current medicinal chemistry trends, where researchers are actively exploring thiazole derivatives for their biological activities. The compound's molecular weight of 219.25 g/mol and its specific chemical formula (C11H9NO2S) contribute to its distinctive characteristics in various applications.

Recent studies highlight the growing importance of thiazole-based compounds in addressing modern healthcare challenges. As researchers investigate novel approaches to drug design and molecular targeting, compounds like 3-(2-Methyl-1,3-thiazol-4-yl)benzoic Acid offer valuable building blocks for developing new therapeutic agents. The compound's carboxylic acid functional group provides opportunities for further derivatization, making it particularly useful in structure-activity relationship studies.

In the pharmaceutical industry, 3-(2-Methyl-1,3-thiazol-4-yl)benzoic Acid serves as a key intermediate for synthesizing more complex molecules. Its applications extend to potential use in developing anti-inflammatory agents, antimicrobial compounds, and other bioactive molecules. The compound's structural features align well with current research into small molecule therapeutics, particularly in areas addressing metabolic disorders and neurological conditions.

The agrochemical sector also benefits from thiazole-containing compounds like 3-(2-Methyl-1,3-thiazol-4-yl)benzoic Acid. As the agricultural industry seeks more effective and environmentally friendly solutions, such molecules contribute to developing new crop protection agents and plant growth regulators. The compound's potential role in creating sustainable agriculture solutions makes it particularly relevant in today's market.

From a synthetic chemistry perspective, 3-(2-Methyl-1,3-thiazol-4-yl)benzoic Acid offers interesting possibilities for organic synthesis and molecular design. Chemists value its versatility as a building block for creating diverse molecular architectures. The compound's stability and reactivity profile make it suitable for various coupling reactions and functional group transformations, which are fundamental in modern drug discovery pipelines.

Market analysis indicates growing demand for specialized chemical intermediates like 3-(2-Methyl-1,3-thiazol-4-yl)benzoic Acid. The global market for fine chemicals and pharmaceutical intermediates continues to expand, driven by increased R&D activities in the life sciences sector. Companies specializing in custom synthesis and contract research are particularly interested in such compounds to support their clients' innovation efforts.

Quality control and characterization of 3-(2-Methyl-1,3-thiazol-4-yl)benzoic Acid involve standard analytical techniques including HPLC, NMR spectroscopy, and mass spectrometry. These methods ensure the compound meets the stringent purity requirements for research and industrial applications. Proper storage conditions and handling procedures are essential to maintain the compound's stability and performance characteristics over time.

As research into heterocyclic chemistry advances, compounds like 3-(2-Methyl-1,3-thiazol-4-yl)benzoic Acid continue to reveal new potential applications. Current investigations explore its use in material science applications, particularly in developing functional materials with specific electronic or optical properties. This expansion into non-pharmaceutical applications demonstrates the compound's versatility across multiple scientific disciplines.

The future outlook for 3-(2-Methyl-1,3-thiazol-4-yl)benzoic Acid appears promising, with ongoing research uncovering novel uses and synthetic pathways. As the scientific community places greater emphasis on molecular diversity and structure-based design, this compound will likely maintain its importance in chemical research and development. Its combination of a benzoic acid scaffold with a thiazole heterocycle offers a unique platform for innovation in multiple scientific and industrial domains.

• 35195-78-9(3-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]benzoic acid)
• 127406-11-5(Benzaldehyde,4-(2-methyl-4-thiazolyl)-)
• 850375-07-4(3-(2-METHYL-THIAZOL-4-YL)-BENZOIC ACID METHYL ESTER)
• 857283-96-6(4-(2-Methyl-1,3-thiazol-4-yl)phenylmethanol)
• 159887-01-1(4-(2-Methyl-thiazol-4-yl)-benzoicacidhydrobromide)
• 60510-56-7(2-(2-Phenyl-1,3-thiazol-4-yl)benzene-carboxylic Acid)
• 65032-66-8(2-(2-Methyl-1,3-thiazol-4-yl)benzoic Acid)
• 850375-05-2(3-(2-methylthiazol-4-yl)benzaldehyde)
• 294620-60-3(4-(2-Methyl-1,3-thiazol-4-yl)benzoic Acid)
• 850375-06-3(3-(2-methyl-1,3-thiazol-4-yl)phenylmethanol)