Cas no 27737-56-0 (Ethyl 4-hydroxy-1H-indole-2-carboxylate)

Ethyl 4-hydroxy-1H-indole-2-carboxylate is a versatile indole derivative widely used in organic synthesis and pharmaceutical research. Its key structural features include a hydroxyl group at the 4-position and an ester moiety at the 2-position, making it a valuable intermediate for the preparation of biologically active compounds. The compound exhibits good stability under standard conditions and offers reactivity at multiple sites, enabling functionalization for diverse applications. Its synthetic utility is further enhanced by compatibility with common reaction conditions, facilitating its incorporation into complex molecular frameworks. Researchers value this compound for its role in developing heterocyclic systems, particularly in medicinal chemistry projects targeting indole-based scaffolds.

Ethyl 4-hydroxy-1H-indole-2-carboxylate structure

27737-56-0 structure

Product Name:Ethyl 4-hydroxy-1H-indole-2-carboxylate

CAS No:27737-56-0

MF:C₁₁H₁₁NO₃

MW:205.209943056107

MDL:MFCD18711665

CID:1084715

PubChem ID:13274763

Update Time:2025-05-27

Ethyl 4-hydroxy-1H-indole-2-carboxylate Chemical and Physical Properties

Names and Identifiers

- Ethyl 4-hydroxy-1H-indole-2-carboxylate
- ethyl 4-hydroxyindole-2-carboxylate
- 1H-Indole-2-carboxylic acid, 4-hydroxy-, ethyl ester
- 4-hydroxy 2-ethoxycarbonyl indole
- 4-hydroxy-1H-indole-2-carboxylic acid ethyl ester
- 4-Hydroxyindol-2-carbonsaeureethylester
- 4-hydroxy-indole-2-carboxylic acid ethyl ester
- AGN-PC-00LT1D
- RP00124
- SureCN913891
- Y8533
- CS-0103602
- J-521014
- AKOS022183508
- Ethyl4-hydroxy-1H-indole-2-carboxylate
- 27737-56-0
- DB-334229
- 2-ethoxycarbonyl-4-hydroxyindole
- MFCD18711665
- SCHEMBL913891
- AS-41888
- ZJZAFABAVBYFQO-UHFFFAOYSA-N
- DTXSID10533935
- CBA73756
- MDL： MFCD18711665
- Inchi： 1S/C11H11NO3/c1-2-15-11(14)9-6-7-8(12-9)4-3-5-10(7)13/h3-6,12-13H,2H2,1H3
- InChI Key： ZJZAFABAVBYFQO-UHFFFAOYSA-N
- SMILES： O(CC)C(C1=CC2C(=CC=CC=2N1)O)=O

Computed Properties

Exact Mass: 205.07393
Monoisotopic Mass: 205.07389321g/mol
Isotope Atom Count: 0
Hydrogen Bond Donor Count: 2
Hydrogen Bond Acceptor Count: 4
Heavy Atom Count: 15
Rotatable Bond Count: 3
Complexity: 244
Covalently-Bonded Unit Count: 1
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count : 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
XLogP3: 2.8
Topological Polar Surface Area: 62.3?2

Experimental Properties

Density: 1.3±0.1 g/cm3
Melting Point: N/A℃
Boiling Point: 410.4±25.0 °C at 760 mmHg
Flash Point: 202.0±23.2 °C
PSA: 62.32
Vapor Pressure: 0.0±1.0 mmHg at 25°C

Ethyl 4-hydroxy-1H-indole-2-carboxylate Security Information

Signal Word：warning
Hazard Statement： H303+H313+H333
Warning Statement： P264+P280+P305+P351+P338+P337+P313
Safety Instruction： H303+H313+H333
Storage Condition：storage at -4℃ (1-2weeks), longer storage period at -20℃ (1-2years)

Ethyl 4-hydroxy-1H-indole-2-carboxylate Pricemore >>

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