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• 2. Development of selective, fluorescent cannabinoid type 2 receptor ligands based on a 1,8-naphthyridin-2-(1H)-one-3-carboxamide scaffold
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• 3. Synthesis of dibenzylamino-1-methylcyclohexanol and dibenzylamino-1-trifluoromethylcyclohexanol isomers
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• Solvents and Organic Chemicals Organic Compounds Alcohol/Ether

Comprehensive Guide to trans-4-Aminocyclohexanol (CAS No. 27489-62-9): Properties, Applications, and Market Insights

trans-4-Aminocyclohexanol (CAS No. 27489-62-9) is a versatile organic compound widely used in pharmaceutical synthesis, agrochemicals, and specialty chemicals. This cyclohexane derivative, characterized by its amino and hydroxyl functional groups in the trans configuration, has gained significant attention due to its unique structural properties and broad applicability. Researchers and industry professionals often search for terms like "trans-4-Aminocyclohexanol synthesis", "CAS 27489-62-9 applications", and "4-Aminocyclohexanol derivatives", reflecting its importance in modern chemistry.

The compound's molecular formula, C₆H₁₃NO, gives it a molar mass of 115.17 g/mol, with a melting point typically ranging between 80-85°C. Its stereochemistry plays a crucial role in its reactivity, making trans-4-Aminocyclohexanol particularly valuable for creating chiral intermediates. Recent studies highlight its growing use in asymmetric synthesis, where questions like "How to separate cis and trans 4-Aminocyclohexanol?" frequently appear in academic discussions.

In pharmaceutical applications, trans-4-Aminocyclohexanol serves as a key building block for various drug molecules. Its structural features enable the development of compounds with improved bioavailability and target specificity. The search trend for "pharmaceutical uses of 4-Aminocyclohexanol" has shown steady growth, particularly in relation to central nervous system (CNS) drugs and antiviral medications. The compound's ability to form stable hydrogen bonds makes it valuable for designing molecules with enhanced binding properties.

The agrochemical industry utilizes trans-4-Aminocyclohexanol in the synthesis of novel pesticides and plant growth regulators. Its cyclohexane backbone provides structural stability while the functional groups allow for diverse chemical modifications. Queries such as "4-Aminocyclohexanol in crop protection" and "eco-friendly agrochemicals from cyclohexanol derivatives" reflect current industry interests in sustainable agricultural solutions.

From a market perspective, the demand for trans-4-Aminocyclohexanol has been increasing steadily, with Asia-Pacific regions showing particularly strong growth. Manufacturers and suppliers frequently search for "high purity 27489-62-9" and "bulk trans-4-Aminocyclohexanol suppliers", indicating robust commercial interest. The compound's price trends and availability are closely monitored by industry analysts, especially in relation to its pharmaceutical applications.

Recent advancements in synthetic methodologies have made trans-4-Aminocyclohexanol more accessible to researchers. Modern catalytic processes have addressed previous challenges in stereoselective synthesis, with searches for "green synthesis of 4-Aminocyclohexanol" becoming increasingly common. These developments align with the chemical industry's broader shift toward sustainable and efficient production methods.

Analytical characterization of trans-4-Aminocyclohexanol typically involves techniques such as HPLC, GC-MS, and NMR spectroscopy. The scientific community often investigates "spectroscopic properties of 27489-62-9" and "analytical methods for cyclohexanol amines", reflecting the compound's importance in quality control and research applications. Proper identification and purity assessment are crucial for its various end-use applications.

Safety considerations for handling trans-4-Aminocyclohexanol include standard laboratory precautions, with particular attention to its potential as a mild irritant. While not classified as hazardous under normal conditions, proper storage conditions (typically cool, dry environments) are recommended to maintain stability. Industrial users frequently search for "27489-62-9 safety data" and "storage guidelines for aminocyclohexanols" to ensure compliance with workplace safety standards.

The future outlook for trans-4-Aminocyclohexanol appears promising, with potential applications emerging in materials science and specialty polymers. Its dual functionality makes it an attractive candidate for developing novel polymeric materials with specific properties. Research interest in "4-Aminocyclohexanol in polymer chemistry" and "smart materials from cyclohexanol derivatives" suggests expanding applications beyond traditional chemical uses.

For researchers working with trans-4-Aminocyclohexanol, understanding its structure-activity relationships is crucial for developing new applications. The compound's conformational flexibility and hydrogen bonding capacity offer numerous possibilities for molecular design. Academic searches for "conformational analysis of 4-Aminocyclohexanol" and "hydrogen bonding patterns in aminocyclohexanols" demonstrate ongoing fundamental interest in these properties.

In conclusion, trans-4-Aminocyclohexanol (CAS No. 27489-62-9) represents a valuable chemical building block with diverse applications across multiple industries. Its unique combination of structural features continues to inspire research and development efforts, particularly in pharmaceutical and agrochemical sectors. As synthetic methods improve and new applications emerge, this compound is likely to maintain its importance in specialty chemical markets worldwide.

• 50910-54-8(trans-4-aminocyclohexanol;hydrochloride)
• 56239-26-0(cis-4-aminocyclohexan-1-ol hydrochloride)
• 40525-78-8(cis-4-aminocyclohexanol)
• 773794-80-2(Cyclohexanol,4-(2-aminopropyl)-)
• 6850-65-3(4-aminocyclohexan-1-ol)
• 760158-03-0(Cycloheptanol,4-amino-, (1S,4R)-)
• 6982-42-9(cis-3-aminocyclohexanol)
• 6850-39-1(3-Aminocyclohexanol)
• 40525-77-7(trans-3-aminocyclohexanol)
• 76445-65-3(4-aminocyclohexan-1-ol hydrochloride)