Cas no 264600-82-0 (2-(di-(t-butoxycarbonyl)amino)pyrimidine)

2-(Di-(t-butoxycarbonyl)amino)pyrimidine is a protected pyrimidine derivative featuring two t-butoxycarbonyl (Boc) groups on the amino functionality. This compound is particularly valuable in organic synthesis and pharmaceutical research, where selective protection of amine groups is required. The Boc groups provide stability under a range of reaction conditions while allowing for facile deprotection under acidic conditions. Its pyrimidine core makes it a useful intermediate in the preparation of nucleoside analogs, heterocyclic compounds, and other biologically active molecules. The steric bulk of the Boc groups also aids in controlling regioselectivity during further functionalization. This reagent is commonly employed in peptide chemistry and medicinal chemistry applications.
2-(di-(t-butoxycarbonyl)amino)pyrimidine structure
264600-82-0 structure
Product Name:2-(di-(t-butoxycarbonyl)amino)pyrimidine
CAS No:264600-82-0
MF:C14H21N3O4
MW:295.334243535995
CID:5796825
Update Time:2025-05-24

2-(di-(t-butoxycarbonyl)amino)pyrimidine Chemical and Physical Properties

Names and Identifiers

    • 2-(di-(t-butoxycarbonyl)amino)pyrimidine
    • Imidodicarbonic acid, 2-(2-pyrimidinyl)-, 1,3-bis(1,1-dimethylethyl) ester
    • Inchi: 1S/C14H21N3O4/c1-13(2,3)20-11(18)17(10-15-8-7-9-16-10)12(19)21-14(4,5)6/h7-9H,1-6H3
    • InChI Key: KKDVUFUTRHECGW-UHFFFAOYSA-N
    • SMILES: N(C1=NC=CC=N1)(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C

Experimental Properties

  • Density: 1.167±0.06 g/cm3(Predicted)
  • Boiling Point: 371.9±25.0 °C(Predicted)
  • pka: -0.66±0.10(Predicted)

2-(di-(t-butoxycarbonyl)amino)pyrimidine Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
eNovation Chemicals LLC
Y1002961-5g
2-(di-(t-butoxycarbonyl)amino)pyrimidine
264600-82-0 95%
5g
$1900 2024-07-24
eNovation Chemicals LLC
Y1002961-5g
2-(di-(t-butoxycarbonyl)amino)pyrimidine
264600-82-0 95%
5g
$1900 2025-02-19
eNovation Chemicals LLC
Y1002961-5g
2-(di-(t-butoxycarbonyl)amino)pyrimidine
264600-82-0 95%
5g
$1900 2025-02-19

Additional information on 2-(di-(t-butoxycarbonyl)amino)pyrimidine

Introduction to 2-(Di-(t-Butoxycarbonyl)Amino)Pyrimidine (CAS No. 264600-82-0)

The compound 2-(Di-(t-Butoxycarbonyl)Amino)Pyrimidine, with CAS number 264600-82-0, is a highly specialized organic molecule that has garnered significant attention in the fields of organic chemistry, pharmacology, and materials science. This compound belongs to the pyrimidine family, which is a class of heterocyclic aromatic compounds known for their diverse applications in drug discovery and advanced materials. The structure of this compound features a pyrimidine ring with a di-t-butoxycarbonylamino group at the 2-position, making it a unique derivative with potential for further functionalization and exploration.

Recent advancements in synthetic methodologies have enabled the efficient synthesis of 2-(Di-(t-Butoxycarbonyl)Amino)Pyrimidine. Researchers have employed various strategies, including microwave-assisted synthesis and catalytic cross-coupling reactions, to optimize its production. These methods not only enhance yield but also improve the purity of the compound, which is critical for its application in sensitive biological assays and material science experiments.

One of the most promising applications of 2-(Di-(t-Butoxycarbonyl)Amino)Pyrimidine lies in its potential as a building block for drug development. Pyrimidines are well-known for their role in nucleic acids and are often used as scaffolds in medicinal chemistry due to their ability to interact with biological targets such as kinases and G-protein coupled receptors (GPCRs). The presence of the di-t-butoxycarbonylamino group introduces additional functionality, enabling researchers to explore its role in modulating enzyme activity or serving as a prodrug component.

Moreover, the compound has shown potential in materials science, particularly in the development of advanced polymers and coatings. The pyrimidine core provides aromatic stability, while the t-butoxycarbonyl groups offer opportunities for cross-linking and surface modification. Recent studies have demonstrated that derivatives of this compound can be incorporated into polymer matrices to enhance mechanical properties and thermal stability, making it a candidate for high-performance materials.

In terms of biological activity, 2-(Di-(t-Butoxycarbonyl)Amino)Pyrimidine has been subjected to preliminary screening against various disease models. Early results suggest that it may exhibit selective cytotoxicity against cancer cell lines, potentially due to its ability to inhibit key enzymes involved in cell proliferation. However, further research is required to validate these findings and explore its mechanism of action.

The synthesis and characterization of 2-(Di-(t-Butoxycarbonyl)Amino)Pyrimidine have been extensively documented in recent scientific literature. Advanced analytical techniques such as nuclear magnetic resonance (NMR), mass spectrometry (MS), and X-ray crystallography have been employed to confirm its structure and purity. These studies underscore the importance of rigorous characterization in ensuring the reliability of experimental results.

In conclusion, 2-(Di-(t-Butoxycarbonyl)Amino)Pyrimidine (CAS No. 264600-82-0) represents a versatile compound with significant potential across multiple disciplines. Its unique structure, combined with recent advances in synthetic and analytical techniques, positions it as a valuable tool for researchers in academia and industry alike. As ongoing studies continue to uncover its properties and applications, this compound is poised to make meaningful contributions to the fields of chemistry, pharmacology, and materials science.

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