Cas no 26272-90-2 (Hexadecyl carbonochloridate)

Hexadecyl carbonochloridate (CAS 4525-33-1) is a long-chain alkyl chloroformate ester, primarily utilized as a versatile reagent in organic synthesis. Its key advantages include its role as an effective acylating agent, enabling the introduction of the hexadecyloxycarbonyl group into target molecules. The compound is particularly valuable in peptide synthesis and lipid modification due to its reactivity with amines and alcohols, forming stable carbamate or ester linkages. Its hydrophobic hexadecyl chain enhances solubility in nonpolar solvents, facilitating reactions in apolar media. Proper handling under anhydrous conditions is essential due to its moisture sensitivity. The reagent is commonly employed in laboratory-scale applications requiring selective acylation or protection of functional groups.
Hexadecyl carbonochloridate structure
Hexadecyl carbonochloridate structure
Product Name:Hexadecyl carbonochloridate
CAS No:26272-90-2
MF:C17H33ClO2
MW:304.895725011826
MDL:MFCD00035954
CID:52895
PubChem ID:87566086
Update Time:2025-06-08

Hexadecyl carbonochloridate Chemical and Physical Properties

Names and Identifiers

    • Hexadecyl carbonochloridate
    • CETYL CHLOROFORMATE
    • CHLOROFORMIC ACID CETYL ESTER
    • CHLOROFORMIC ACID HEXADECYL ESTER
    • CHLOROFORMIC ACID N-HEXADECYL ESTER
    • HEXADECYL CHLOROCARBONATE
    • HEXADECYL CHLOROFORMATE
    • carbonochloridicacid,hexadecylester
    • Chloroformic acid n-hexadeyl ester
    • n-Hexadecyl chloroformate
    • Palmityl chloroformate
    • Chlorameisensaeure-hexadecylester
    • chlorocarbonic acid hexadecyl ester
    • Chlorokohlensaeure-hexadecylester
    • Kohlensaeure-chlorid-hexadecylester
    • Chloroformicacidhexylester
    • MFCD00035954
    • SCHEMBL82166
    • Cetyl chloroformate, 96%
    • 26272-90-2
    • starbld0016559
    • LS-14613
    • FT-0638590
    • EC 247-578-2
    • D89347
    • Chloroformic acid n-hexadecyl ester pound>>Hexadecyl chloroformate
    • BBA27290
    • HOQUWXSARQBQCW-UHFFFAOYSA-N
    • NS00004393
    • Carbonochloridic acid, hexadecyl ester
    • WRC65MY1ID
    • DTXSID9067194
    • C1053
    • hexadecyloxycarbonylchloride
    • NSC-137911
    • NSC137911
    • NSC 137911
    • J-016360
    • Q27292789
    • palmityloxycarbonyl chloride
    • UNII-WRC65MY1ID
    • FORMIC ACID, CHLORO-, HEXADECYL ESTER
    • AKOS015901909
    • EINECS 247-578-2
    • DB-046915
    • MDL: MFCD00035954
    • Inchi: 1S/C17H33ClO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-20-17(18)19/h2-16H2,1H3
    • InChI Key: HOQUWXSARQBQCW-UHFFFAOYSA-N
    • SMILES: ClC(=O)OCCCCCCCCCCCCCCCC

Computed Properties

  • Exact Mass: 304.21700
  • Monoisotopic Mass: 304.217
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 20
  • Rotatable Bond Count: 16
  • Complexity: 207
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Surface Charge: 0
  • Tautomer Count: nothing
  • XLogP3: nothing
  • Topological Polar Surface Area: 26.3A^2

Experimental Properties

  • Color/Form: Not determined
  • Density: 0.923
  • Boiling Point: 367.1 °C at 760 mmHg
  • Flash Point: >110 oC
  • Refractive Index: 1.4480
  • PSA: 26.30000
  • LogP: 6.84310
  • Solubility: Not determined

Hexadecyl carbonochloridate Security Information

Hexadecyl carbonochloridate Customs Data

  • HS CODE:2915900090
  • Customs Data:

    China Customs Code:

    2915900090

    Overview:

    2915900090. Other saturated acyclic monocarboxylic acids and their anhydrides(Acyl halide\Peroxygenation)Chemicals\Peroxy acid and its halogenation\nitrification\sulfonation\Nitrosative derivative. VAT:17.0%. Tax refund rate:9.0%. Regulatory conditions:AB(Customs clearance form for Inbound Goods,Customs clearance form for outbound goods). MFN tariff:5.5%. general tariff:30.0%

    Declaration elements:

    Product Name, component content, use to

    Regulatory conditions:

    A.Customs clearance form for Inbound Goods
    B.Customs clearance form for outbound goods

    Inspection and quarantine category:

    R.Sanitary supervision and inspection of imported food
    S.Sanitary supervision and inspection of exported food
    M.Import commodity inspection
    N.Export commodity inspection

    Summary:

    2915900090 other saturated acyclic monocarboxylic acids and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:5.5% General tariff:30.0%

Hexadecyl carbonochloridate Pricemore >>

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Hexadecyl carbonochloridate Suppliers

Suzhou Senfeida Chemical Co., Ltd
Gold Member
Audited Supplier Audited Supplier
(CAS:26272-90-2)Cetyl chloroformate
Order Number:sfd13683
Stock Status:in Stock
Quantity:200kg
Purity:99.9%
Pricing Information Last Updated:Friday, 19 July 2024 14:36
Price ($):discuss personally
Tiancheng Chemical (Jiangsu) Co., Ltd
Gold Member
Audited Supplier Audited Supplier
(CAS:26272-90-2)氯甲酸十六烷基酯
Order Number:LE24979542
Stock Status:in Stock
Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Friday, 20 June 2025 12:48
Price ($):discuss personally

Hexadecyl carbonochloridate Related Literature

Additional information on Hexadecyl carbonochloridate

Hexadecyl Carbonochloridate (CAS No. 26272-90-2): An Overview of Its Properties, Applications, and Recent Research

Hexadecyl carbonochloridate (CAS No. 26272-90-2) is a versatile compound with a wide range of applications in various industries, including pharmaceuticals, cosmetics, and materials science. This compound is characterized by its unique chemical structure, which consists of a long alkyl chain attached to a chloroformate group. The combination of these functional groups imparts specific properties that make it valuable for numerous applications.

The chemical formula of Hexadecyl carbonochloridate is C16H33ClO2, and it is a colorless to pale yellow liquid at room temperature. Its molecular weight is approximately 284.88 g/mol. The compound is soluble in many organic solvents but has limited solubility in water, which can be advantageous in certain formulations where controlled solubility is desired.

One of the key properties of Hexadecyl carbonochloridate is its reactivity. The chloroformate group can readily react with alcohols to form esters, making it useful as a coupling agent in synthetic chemistry. This reactivity is particularly valuable in the synthesis of complex molecules and polymers, where precise control over the reaction conditions is essential.

In the pharmaceutical industry, Hexadecyl carbonochloridate has been explored for its potential use in drug delivery systems. Recent studies have shown that this compound can be used to modify the surface properties of nanoparticles, enhancing their stability and bioavailability. For example, a study published in the Journal of Controlled Release demonstrated that Hexadecyl carbonochloridate-modified nanoparticles exhibited improved drug loading efficiency and sustained release profiles compared to unmodified nanoparticles.

In the field of cosmetics, Hexadecyl carbonochloridate is used as an emulsifier and stabilizer in formulations such as creams and lotions. Its ability to form stable emulsions makes it an attractive ingredient for products that require long-term stability and a smooth texture. Additionally, its low toxicity and skin compatibility make it suitable for use in personal care products.

The material science applications of Hexadecyl carbonochloridate are also noteworthy. It has been used as a modifier for polymers to improve their mechanical properties and thermal stability. A recent study published in Polymer Chemistry reported that the incorporation of Hexadecyl carbonochloridate into polymeric materials resulted in enhanced tensile strength and reduced thermal degradation temperatures.

Safety and environmental considerations are crucial when handling any chemical compound. While Hexadecyl carbonochloridate is generally considered safe for industrial use, proper handling and storage practices should be followed to minimize any potential risks. It is important to consult material safety data sheets (MSDS) for detailed information on safe handling procedures and disposal methods.

In conclusion, Hexadecyl carbonochloridate (CAS No. 26272-90-2) is a multifunctional compound with diverse applications across various industries. Its unique chemical structure and reactivity make it an essential component in synthetic chemistry, drug delivery systems, cosmetics, and materials science. Ongoing research continues to uncover new applications and improve our understanding of its properties and behavior.

Recommended suppliers
Suzhou Senfeida Chemical Co., Ltd
(CAS:26272-90-2)Cetyl chloroformate
sfd13683
Purity:99.9%
Quantity:200kg
Price ($):Inquiry
Email
Tiancheng Chemical (Jiangsu) Co., Ltd
(CAS:26272-90-2)氯甲酸十六烷基酯
LE24979542
Purity:99%
Quantity:25KG,200KG,1000KG
Price ($):Inquiry
Email