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Dodecyl Carbonochloridate (CAS No. 24460-74-0): An Overview of Its Properties, Applications, and Recent Research

Dodecyl carbonochloridate (CAS No. 24460-74-0) is a versatile organic compound with a wide range of applications in various industries, including pharmaceuticals, cosmetics, and materials science. This compound is characterized by its unique chemical structure, which consists of a long alkyl chain and a chloroformate functional group. The combination of these features endows Dodecyl carbonochloridate with valuable properties such as solubility, reactivity, and stability.

The chemical formula of Dodecyl carbonochloridate is C₁₂H₂₅OCl. It is a colorless to pale yellow liquid with a mild odor. The compound has a molecular weight of approximately 218.8 g/mol and a boiling point around 190-195°C at 760 mmHg. These physical properties make it suitable for use in various industrial processes where controlled reactivity and solubility are required.

In the pharmaceutical industry, Dodecyl carbonochloridate is often used as an intermediate in the synthesis of drugs and other bioactive compounds. Its reactivity with primary and secondary amines allows for the formation of carbamates, which are important building blocks in drug design. Recent research has shown that carbamates derived from Dodecyl carbonochloridate can exhibit potent biological activities, including anti-inflammatory and anti-cancer properties.

One notable study published in the Journal of Medicinal Chemistry explored the use of Dodecyl carbonochloridate-derived carbamates in the development of novel anti-inflammatory agents. The researchers synthesized a series of carbamates and evaluated their efficacy in inhibiting pro-inflammatory cytokines such as TNF-α and IL-6. The results demonstrated that several compounds showed significant anti-inflammatory activity, suggesting potential applications in the treatment of inflammatory diseases.

In addition to its pharmaceutical applications, Dodecyl carbonochloridate is also used in the cosmetics industry as an emulsifier and stabilizer. Its ability to form stable emulsions makes it useful in the formulation of creams, lotions, and other personal care products. Recent advancements in green chemistry have led to the development of more sustainable methods for producing Dodecyl carbonochloridate, reducing its environmental impact while maintaining its performance characteristics.

A study published in the Green Chemistry Journal described a novel process for synthesizing Dodecyl carbonochloridate using environmentally friendly catalysts and solvents. The researchers reported that this method significantly reduced waste generation and energy consumption compared to traditional synthesis routes. This approach aligns with the growing demand for sustainable chemical processes in both industrial and academic settings.

In materials science, Dodecyl carbonochloridate is used as a coupling agent to improve the adhesion between organic and inorganic materials. Its ability to form strong covalent bonds with both types of surfaces makes it valuable in applications such as coatings, adhesives, and composites. Recent research has focused on optimizing the use of Dodecyl carbonochloridate in these applications to enhance performance and durability.

A study published in the Journal of Applied Polymer Science investigated the use of Dodecyl carbonochloridate-based coupling agents in improving the mechanical properties of polymer composites. The researchers found that incorporating these coupling agents led to significant improvements in tensile strength and impact resistance, making them suitable for use in high-performance applications such as aerospace and automotive industries.

In conclusion, Dodecyl carbonochloridate (CAS No. 24460-74-0) is a multifunctional compound with diverse applications across various industries. Its unique chemical structure and properties make it an essential component in pharmaceuticals, cosmetics, and materials science. Ongoing research continues to uncover new uses and improvements for this compound, highlighting its importance in modern chemistry and technology.

• 638-41-5(n-Pentyl Chloroformate)
• 51637-93-5(Carbonochloridic Acid Octadecyl Ester)
• 56677-60-2(tetradecyl chloroformate)
• 51772-87-3(Carbonochloridic acid, 1,8-octanediyl ester (9CI))
• 2916-20-3(Hexamethylene bis(chloroformate))
• 26272-90-2(Hexadecyl carbonochloridate)
• 2157-16-6(Carbonochloridic acid,C,C'-1,4-butanediyl ester)
• 33758-34-8(Heptyl chloroformate)
• 592-34-7(Butyl chloroformate)
• 56757-75-6(Carbonochloridic acid,C,C'-1,10-decanediyl ester)