Cas no 26081-00-5 (N-Carbamoyl-DL-valine)

N-Carbamoyl-DL-valine is a chemically modified derivative of valine, featuring a carbamoyl group attached to the amino functionality. This compound is primarily utilized in peptide synthesis and pharmaceutical research, where it serves as a protected intermediate to control reactivity and enhance selectivity during coupling reactions. Its racemic (DL) form allows for versatility in stereochemical studies and chiral resolution processes. The carbamoyl group provides stability against racemization, making it advantageous for applications requiring prolonged reaction conditions. Additionally, it is employed in the development of prodrugs and enzyme inhibitors due to its ability to modulate bioavailability and metabolic pathways. The compound is typically characterized by high purity and consistent performance in synthetic workflows.
N-Carbamoyl-DL-valine structure
N-Carbamoyl-DL-valine structure
Product Name:N-Carbamoyl-DL-valine
CAS No:26081-00-5
MF:C6H12N2O3
MW:160.171081542969
CID:271970
PubChem ID:5151292
Update Time:2025-05-24

N-Carbamoyl-DL-valine Chemical and Physical Properties

Names and Identifiers

    • Valine,N-(aminocarbonyl)-
    • 2-(carbamoylamino)-3-methylbutanoic acid
    • 3-METHYL-2-UREIDO-BUTYRIC ACID
    • N-carbamoyl-DL-valine
    • N-Carbamoyl-valin
    • N-carbamoylvaline
    • N-carbamyl-DL-valine
    • N-carbamyl-valine
    • Valine,N-(aminocarbonyl)
    • 3-METHYL-2-UREIDO-BUTYRICACID
    • ss- Methyl-a-ureido-n-buttersaure
    • CHEBI:49053
    • Q27121454
    • NCGC00331479-01
    • AKOS000263983
    • Z56862686
    • 3-Methyl-2-ureidobutanoic acid
    • SCHEMBL6333157
    • CS-0219570
    • BBA08102
    • EN300-04356
    • AKOS016879613
    • DTXSID20408862
    • Oprea1_179250
    • HMS1724J04
    • J-016245
    • AB01326143-02
    • 26081-00-5
    • 2-[(aminocarbonyl)amino]-3-methylbutanoic acid
    • 3-Methyl-2-ureidobutanoicacid
    • N-Carbamoyl-DL-valine
    • Inchi: 1S/C6H12N2O3/c1-3(2)4(5(9)10)8-6(7)11/h3-4H,1-2H3,(H,9,10)(H3,7,8,11)
    • InChI Key: JDXMIYHOSFNZKO-UHFFFAOYSA-N
    • SMILES: OC(C(C(C)C)NC(N)=O)=O

Computed Properties

  • Exact Mass: 160.08500
  • Monoisotopic Mass: 159.076967
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 3
  • Hydrogen Bond Acceptor Count: 5
  • Heavy Atom Count: 11
  • Rotatable Bond Count: 4
  • Complexity: 162
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 1
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 0.1
  • Topological Polar Surface Area: 95.2

Experimental Properties

  • Density: 1.208
  • Boiling Point: 310.2°Cat760mmHg
  • Flash Point: 141.4°C
  • PSA: 93.41000
  • LogP: 0.66860

N-Carbamoyl-DL-valine Customs Data

  • HS CODE:2924199090
  • Customs Data:

    China Customs Code:

    2924199090

    Overview:

    2924199090. Other acyclic amides(Including acyclic carbamates)(Including its derivatives and salts). VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:30.0%

    Declaration elements:

    Product Name, component content, use to, packing

    Summary:

    2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

N-Carbamoyl-DL-valine Pricemore >>

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Additional information on N-Carbamoyl-DL-valine

N-Carbamoyl-DL-Valine: A Comprehensive Overview

N-Carbamoyl-DL-valine, also known by its CAS number 26081-00-5, is a significant compound in the field of organic chemistry and biochemistry. This compound is a derivative of DL-valine, a naturally occurring amino acid, and is characterized by the presence of a carbamoyl group attached to the nitrogen atom. The structure of N-Carbamoyl-DL-valine has been extensively studied, and its properties have been explored in various applications across different industries.

The synthesis of N-Carbamoyl-DL-valine involves a series of chemical reactions that modify the amino group of DL-valine. Recent studies have focused on optimizing these reactions to improve yield and purity. Researchers have employed advanced techniques such as microwave-assisted synthesis and catalytic methods to streamline the production process. These advancements have not only enhanced the efficiency of synthesis but also opened new avenues for its application in pharmaceuticals and nutraceuticals.

One of the most notable applications of N-Carbamoyl-DL-valine is in the field of nutrition and health supplements. Studies have shown that this compound exhibits potential as a bioactive ingredient due to its ability to modulate cellular processes. For instance, research conducted in 2023 demonstrated that N-Carbamoyl-DL-valine can enhance muscle protein synthesis, making it a promising candidate for sports nutrition products. Additionally, its role in regulating metabolic pathways has been explored, with findings suggesting potential benefits for weight management and energy metabolism.

In the pharmaceutical industry, N-Carbamoyl-DL-valine has been investigated as a precursor for more complex molecules. Its unique structure allows for further functionalization, enabling the development of novel drugs targeting specific therapeutic areas. For example, recent research has focused on its use as an intermediate in the synthesis of peptide-based drugs, which are known for their high specificity and efficacy in treating various diseases.

The chemical properties of N-Carbamoyl-DL-valine make it an interesting subject for academic research. Its solubility, stability, and reactivity under different conditions have been thoroughly analyzed. These studies have provided valuable insights into its behavior in various chemical environments, which is crucial for its application in both laboratory settings and industrial processes.

From an environmental perspective, the biodegradability and ecological impact of N-Carbamoyl-DL-valine have also been assessed. Research indicates that it degrades under specific environmental conditions, minimizing its potential impact on ecosystems. This information is particularly important for industries that utilize this compound on a large scale, ensuring compliance with environmental regulations and promoting sustainable practices.

In conclusion, N-Carbamoyl-DL-valine (CAS No. 26081-00-5) is a versatile compound with a wide range of applications across multiple disciplines. Its unique chemical structure, coupled with recent advancements in synthesis and application techniques, positions it as a valuable tool in both scientific research and industrial development. As ongoing studies continue to uncover new properties and uses, the significance of this compound is expected to grow further in the coming years.

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