Cas no 2598-30-3 (8-Hydroxyquinoline-5-carbaldehyde)

8-Hydroxyquinoline-5-carbaldehyde is a versatile heterocyclic compound featuring both hydroxyquinoline and aldehyde functional groups. Its key advantages include strong chelating properties, making it useful in metal ion coordination and analytical chemistry applications. The aldehyde group at the 5-position allows for further derivatization, enabling its use as a precursor in synthesizing Schiff bases, ligands, and other functionalized compounds. This compound exhibits stability under standard conditions and is soluble in common organic solvents, facilitating its use in research and industrial processes. Its structural features also lend utility in fluorescence studies, catalysis, and material science.
8-Hydroxyquinoline-5-carbaldehyde structure
2598-30-3 structure
Product Name:8-Hydroxyquinoline-5-carbaldehyde
CAS No:2598-30-3
MF:C10H7NO2
MW:173.168082475662
MDL:MFCD03425064
CID:290081
PubChem ID:275363
Update Time:2025-10-18

8-Hydroxyquinoline-5-carbaldehyde Chemical and Physical Properties

Names and Identifiers

    • 8-Hydroxyquinoline-5-carbaldehyde
    • 5-Quinolinecarboxaldehyde,8-hydroxy-
    • 5-aldehyde-8-hydroxyquinoline
    • 5-formyl-8-hydroxyquinoline
    • 8-hydroxy-5-formyl-quinoline
    • 8-hydroxy-5-quinolinecarboxaldehyde
    • 8-hydroxyquinoline-5-carboxaldehyde
    • 8-Hydroxyquinoline-5-carboxyaldehyde
    • 8-oxidanylquinoline-5-carbaldehyde
    • AC1L5HHN
    • AC1Q6Q72
    • CTK4F6893
    • HMS2862A16
    • NSC122131
    • 8-HYDROXY-QUINOLINE-5-CARBALDEHYDE
    • EN300-225868
    • MFCD03425064
    • MLS000737539
    • 2598-30-3
    • CHEMBL1487639
    • SCHEMBL700910
    • DS-4609
    • AKOS005208275
    • 8-hydroxyquinoline-5-carbaldehyde;3-((4-Chloro-2-methylphenyl)carbamoyl)naphthalen-2-yl dihydrogen phosphate
    • DTXSID70298275
    • BDBM50568049
    • 5-formyl-8-hydroxychinolin
    • 8-hydroxy-quinoline-5-carbaldehyde, AldrichCPR
    • A818232
    • NSC-122131
    • 5-Quinolinecarboxaldehyde, 8-hydroxy-
    • LIADJWREMDHKHQ-UHFFFAOYSA-N
    • SB67525
    • A877403
    • SMR000528556
    • SY106953
    • CS-W007202
    • 5-Formyl-8-hydroxyquinoline; 5-Formyl-8-quinolinol; 8-Hydroxyquinoline-5-carbaldehyde; 8-Hydroxyquinoline-5-carboxaldehyde; NSC 122131;
    • 8QUINOLINOL5FORMYL
    • MDL: MFCD03425064
    • Inchi: 1S/C10H7NO2/c12-6-7-3-4-9(13)10-8(7)2-1-5-11-10/h1-6,13H
    • InChI Key: LIADJWREMDHKHQ-UHFFFAOYSA-N
    • SMILES: OC1=CC=C(C=O)C2=CC=CN=C21

Computed Properties

  • Exact Mass: 173.04771
  • Monoisotopic Mass: 173.048
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 13
  • Rotatable Bond Count: 1
  • Complexity: 195
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 1.7
  • Topological Polar Surface Area: 50.2A^2

Experimental Properties

  • Density: 1.364
  • Boiling Point: 383.1°C at 760 mmHg
  • Flash Point: 185.5°C
  • Refractive Index: 1.733
  • PSA: 50.19
  • LogP: 1.75290

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8-Hydroxyquinoline-5-carbaldehyde Suppliers

Tiancheng Chemical (Jiangsu) Co., Ltd
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(CAS:2598-30-3)8-Hydroxyquinoline-5-carbaldehyde
Order Number:LE7564
Stock Status:in Stock
Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Friday, 20 June 2025 11:57
Price ($):discuss personally

Additional information on 8-Hydroxyquinoline-5-carbaldehyde

Comprehensive Analysis of 8-Hydroxyquinoline-5-carbaldehyde (CAS No. 2598-30-3): Properties, Applications, and Innovations

8-Hydroxyquinoline-5-carbaldehyde (CAS No. 2598-30-3) is a versatile organic compound widely recognized for its unique chemical structure and broad applicability in pharmaceuticals, agrochemicals, and material science. This hydroxyquinoline derivative features a hydroxyl group at the 8-position and a formyl group at the 5-position, making it a valuable intermediate in synthetic chemistry. Its molecular formula, C10H7NO2, and molecular weight of 173.17 g/mol underscore its compact yet reactive nature.

In recent years, the demand for 8-Hydroxyquinoline-5-carbaldehyde has surged due to its role in developing antimicrobial agents and chelation therapies. Researchers are particularly interested in its potential to address antibiotic resistance, a pressing global health concern. The compound's ability to bind metal ions also makes it a candidate for catalytic applications and sensor technologies, aligning with the growing focus on sustainable chemistry.

From a synthetic perspective, 8-Hydroxyquinoline-5-carbaldehyde serves as a precursor for heterocyclic compounds and ligand systems. Its aldehyde functionality allows for condensation reactions, enabling the creation of Schiff bases—a class of compounds with demonstrated bioactivity. This versatility has spurred innovations in drug discovery, where modified quinoline scaffolds are explored for their pharmacokinetic properties.

Environmental and safety considerations are paramount when handling 8-Hydroxyquinoline-5-carbaldehyde. While not classified as hazardous under standard regulations, proper storage in cool, dry conditions is recommended to maintain stability. The compound’s low ecotoxicity profile further enhances its appeal for industrial applications, particularly in green chemistry initiatives.

Market trends indicate rising interest in 8-Hydroxyquinoline-5-carbaldehyde for electronic materials, such as organic light-emitting diodes (OLEDs). Its electron-withdrawing properties contribute to charge transport efficiency, a critical factor in next-generation displays. Additionally, the compound’s fluorescence characteristics are being investigated for bioimaging probes, addressing the need for non-invasive diagnostic tools.

In conclusion, 8-Hydroxyquinoline-5-carbaldehyde (CAS No. 2598-30-3) exemplifies the intersection of traditional chemistry and modern innovation. Its multifaceted applications—from pharmaceutical intermediates to advanced materials—highlight its enduring relevance in scientific research and industrial development. As sustainability and functionality drive chemical innovation, this compound is poised to remain a cornerstone of interdisciplinary progress.

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Tiancheng Chemical (Jiangsu) Co., Ltd
(CAS:2598-30-3)8-Hydroxyquinoline-5-carbaldehyde
LE7564
Purity:99%
Quantity:25KG,200KG,1000KG
Price ($):Inquiry
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