Cas no 1028-71-3 (5-benzoylquinolin-8-ol)

5-Benzoylquinolin-8-ol is a quinoline derivative characterized by the presence of a benzoyl group at the 5-position and a hydroxyl group at the 8-position. This compound is of interest in coordination chemistry due to its ability to act as a bidentate ligand, forming stable complexes with various metal ions. Its structural features also make it a potential intermediate in the synthesis of more complex heterocyclic compounds. The benzoyl moiety enhances its lipophilicity, which may be advantageous in applications requiring solubility in organic matrices. Additionally, the hydroxyl group provides a reactive site for further functionalization, expanding its utility in synthetic chemistry.
5-benzoylquinolin-8-ol structure
5-benzoylquinolin-8-ol structure
Product Name:5-benzoylquinolin-8-ol
CAS No:1028-71-3
MF:C16H11NO2
MW:249.264044046402
CID:216205
PubChem ID:241492
Update Time:2025-10-24

5-benzoylquinolin-8-ol Chemical and Physical Properties

Names and Identifiers

    • Methanone,(8-hydroxy-5-quinolinyl)phenyl-
    • (8-hydroxyquinolin-5-yl)-phenylmethanone
    • (8-Hydroxy-[5]chinolyl)-phenyl-keton
    • (8-hydroxy-[5]quinolyl)-phenyl ketone
    • 5-Benzoyl-8-chinolinol
    • 5-benzoyl-8-hydroxy quinoline
    • 5-Benzoyl-8-hydroxy-chinolin
    • 5-benzoyl-8-quinolinol
    • 8-Hydroxy-5-quinolyl phenyl ketone
    • AC1L67HE
    • AC1Q5EBG
    • AG-J-70583
    • AR-1H4619
    • CTK4A1563
    • NSC48892
    • 5-benzoylquinolin-8-ol
    • JVHWRVMKLLDQHF-UHFFFAOYSA-N
    • 1028-71-3
    • SCHEMBL10582092
    • EN300-1276692
    • DTXSID60287097
    • NSC-48892
    • (8-hydroxyquinolin-5-yl)phenylmethanone
    • AKOS019823279
    • (8-hydroxy-5-quinolyl)-phenyl-methanone
    • Inchi: 1S/C16H11NO2/c18-14-9-8-13(12-7-4-10-17-15(12)14)16(19)11-5-2-1-3-6-11/h1-10,18H
    • InChI Key: JVHWRVMKLLDQHF-UHFFFAOYSA-N
    • SMILES: OC1=CC=C(C(C2C=CC=CC=2)=O)C2=CC=CN=C21

Computed Properties

  • Exact Mass: 249.07903
  • Monoisotopic Mass: 249.078978594g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 19
  • Rotatable Bond Count: 2
  • Complexity: 325
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 3.6
  • Topological Polar Surface Area: 50.2?2

Experimental Properties

  • PSA: 50.19

5-benzoylquinolin-8-ol Pricemore >>

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5-benzoylquinolin-8-ol Related Literature

Additional information on 5-benzoylquinolin-8-ol

Comprehensive Overview of 5-Benzoylquinolin-8-ol (CAS No. 1028-71-3): Properties, Applications, and Industry Insights

5-Benzoylquinolin-8-ol (CAS No. 1028-71-3) is a specialized organic compound with a molecular formula of C16H11NO2. This quinoline derivative features a benzoyl group at the 5-position and a hydroxyl group at the 8-position, which contribute to its unique chemical reactivity and functional versatility. Researchers and industries value this compound for its potential in pharmaceutical intermediates, coordination chemistry, and material science. Its structural motif is increasingly studied for applications in fluorescence probes and metal ion chelators, aligning with current trends in sustainable chemistry and green synthesis.

The growing interest in heterocyclic compounds like 5-benzoylquinolin-8-ol is driven by their role in drug discovery and catalysis. Recent publications highlight its utility in designing antimicrobial agents and anticancer scaffolds, addressing global health challenges. Users frequently search for "quinoline derivatives uses" or "CAS 1028-71-3 supplier," reflecting demand in both academic and industrial sectors. The compound’s solubility in organic solvents (e.g., DMSO, ethanol) and stability under controlled conditions make it a practical choice for lab-scale experiments.

From an SEO perspective, this content targets high-value keywords such as "5-benzoylquinolin-8-ol synthesis," "1028-71-3 safety data," and "quinoline-based chelators." These terms resonate with professionals seeking technical specifications or application case studies. Notably, the compound’s photophysical properties are under investigation for OLED materials, a hotspot in renewable energy research. This aligns with user queries like "organic electronics compounds" and "quinoline fluorescence."

Quality control of 5-benzoylquinolin-8-ol involves HPLC purity analysis and spectroscopic characterization (FTIR, NMR). Suppliers often emphasize batch-to-batch consistency, a critical factor for reproducibility in medicinal chemistry. Environmental considerations also drive interest in biodegradable quinoline derivatives, linking to searches for "eco-friendly chemical alternatives." Regulatory compliance (e.g., REACH, FDA guidelines) further underscores its safe handling protocols.

In summary, 5-benzoylquinolin-8-ol (CAS No. 1028-71-3) bridges fundamental research and industrial innovation. Its adaptability to cross-coupling reactions and ligand design positions it as a valuable tool for scientists exploring next-generation functional materials. By integrating trending topics like AI-assisted molecular design and circular economy, this overview meets the evolving needs of its audience while maintaining rigorous scientific accuracy.

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