Cas no 2587-76-0 (Tri-n-octylchlorotin)
Tri-n-octylchlorotin Chemical and Physical Properties
Names and Identifiers
-
- Tri-n-octylchlorotin
- Trioctyltin chloride
- chloro(trioctyl)stannane
- Tri-n-octyltin chloride
- Tri-n-octyltin chlorideneat
- Chlorotrioctylstannane
- Chlorotrioctyltin
- EINECS 219-969-8
- Stannane,chlorotrioctyl
- Tin,chlorotrioctyl
- Trioctyl-chlorstannan
- Trioctyltin chloride (6 CI)
- Trioctylzinnchlorid
- Stannane,chlorotrioctyl-
- MFCD00043327
- FT-0753756
- Tin, chlorotrioctyl-
- MCNGJXAXOJDJKO-UHFFFAOYSA-M
- Q27251878
- 176VII0B0K
- 2587-76-0
- SCHEMBL733440
- NSC65479
- Trioctyltin chloride 1000 microg/mL in Methanol
- AKOS015839916
- Stannane, chlorotrioctyl-
- ?Trioctyltin chloride
- UNII-176VII0B0K
- J-016158
- NS00046722
- NSC 65479
- TRIOCTYLCHLOROSTANNANE
- DTXSID3029657
- tri-n-Octylchlorotin- tech 95%
- BRN 4133182
- NSC-65479
- Tin, chlorotrioctyl-(7CI)
- DTXCID409657
- FT146360
-
- MDL： MFCD00043327
- Inchi： 1S/3C8H17.ClH.Sn/c3*1-3-5-7-8-6-4-2;;/h3*1,3-8H2,2H3;1H;/q;;;;+1/p-1
- InChI Key： MCNGJXAXOJDJKO-UHFFFAOYSA-M
- SMILES： [Sn](CCCCCCCC)(CCCCCCCC)(CCCCCCCC)Cl
Computed Properties
- Exact Mass: 494.27000
- Monoisotopic Mass: 494.27
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 0
- Heavy Atom Count: 26
- Rotatable Bond Count: 15
- Complexity: 226
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Surface Charge: 0
- Tautomer Count: nothing
- XLogP3: nothing
- Topological Polar Surface Area: 0A^2
Experimental Properties
- Density: 1.04
- Boiling Point: 469.2°Cat760mmHg
- Flash Point: 100?°C
- Refractive Index: 1.482
- PSA: 0.00000
- LogP: 10.25220
Tri-n-octylchlorotin Security Information
- Hazardous Material transportation number：UN 3265
- WGK Germany：1
- Hazard Category Code： R36/37/38;R53
- Safety Instruction： S61
- FLUKA BRAND F CODES：10-21
- RTECS：WH6855000
-
Hazardous Material Identification：
- Packing Group：III
- Hazard Level：6.1(b)
- Risk Phrases：R36/37/38; R53
- Packing Group：III
- Safety Term：6.1(b)
- HazardClass：6.1(b)
- PackingGroup：III
- TSCA：Yes
Tri-n-octylchlorotin Customs Data
- HS CODE：2931900090
- Customs Data：
China Customs Code:
2931900090Overview:
2931900090. Other organic-Inorganic compound. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:AB(Customs clearance form for Inbound Goods,Customs clearance form for outbound goods). MFN tariff:6.5%. general tariff:30.0%
Summary:
2931900090. other organo-inorganic compounds. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0%
Tri-n-octylchlorotin Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| TRC | T886295-25mg |
Tri-n-octylchlorotin |
2587-76-0 | 25mg |
$ 788.00 | 2023-09-05 | ||
| TRC | T886295-50mg |
Tri-n-octylchlorotin |
2587-76-0 | 50mg |
$ 1401.00 | 2023-09-05 | ||
| TRC | T886295-100mg |
Tri-n-octylchlorotin |
2587-76-0 | 100mg |
$ 200.00 | 2022-03-29 | ||
| TRC | T886295-250mg |
Tri-n-octylchlorotin |
2587-76-0 | 250mg |
$ 695.00 | 2022-06-02 | ||
| TRC | T886296-25mg |
Tri-n-octylchlorotin (~85%) |
2587-76-0 | 25mg |
$ 80.00 | 2023-02-03 | ||
| TRC | T886296-50mg |
Tri-n-octylchlorotin (~85%) |
2587-76-0 | 50mg |
$ 150.00 | 2023-02-03 | ||
| TRC | T886296-100mg |
Tri-n-octylchlorotin (~85%) |
2587-76-0 | 100mg |
$ 280.00 | 2023-02-03 | ||
| TRC | T886296-250mg |
Tri-n-octylchlorotin (~85%) |
2587-76-0 | 250mg |
$ 610.00 | 2023-02-03 | ||
| BAI LING WEI Technology Co., Ltd. | DRE-C17892000-25mg |
Trioctyltin chloride |
2587-76-0 | 25mg |
￥ 2384 | 2022-04-26 | ||
| TRC | T886295-500mg |
Tri-n-octylchlorotin |
2587-76-0 | 500mg |
$ 1200.00 | 2022-06-02 |
Tri-n-octylchlorotin Suppliers
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Tri-n-octylchlorotin Related Literature
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Luke L. Lairson,Warren W. Wakarchuk Chem. Commun., 2007, 365-367
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Bidou Wang,Xifeng Chen Analyst, 2014,139, 5695-5699
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Juan J. Sánchez,Miguel López-Haro,Juan C. Hernández-Garrido,Ginesa Blanco,Miguel A. Cauqui,José M. Rodríguez-Izquierdo,José A. Pérez-Omil,José J. Calvino,María P. Yeste J. Mater. Chem. A, 2019,7, 8993-9003
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Cheng Fang,Jinjian Wu,Zahra Sobhani,Md. Al Amin,Youhong Tang Anal. Methods, 2019,11, 163-170
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R. M. Pemberton,J. P. Hart,T. T. Mottram Analyst, 2001,126, 1866-1871
Additional information on Tri-n-octylchlorotin
Research Brief on Tri-n-octylchlorotin (CAS: 2587-76-0): Recent Advances and Applications in Chemical Biology and Medicine
Tri-n-octylchlorotin (CAS: 2587-76-0) is an organotin compound that has garnered significant attention in recent years due to its potential applications in chemical biology and medicinal chemistry. Organotin compounds, characterized by the presence of tin-carbon bonds, have been extensively studied for their diverse biological activities, including antimicrobial, antitumor, and catalytic properties. This research brief aims to provide an overview of the latest findings related to Tri-n-octylchlorotin, focusing on its synthesis, mechanistic insights, and therapeutic potential.
Recent studies have highlighted the role of Tri-n-octylchlorotin as a versatile intermediate in the synthesis of more complex organotin derivatives. A 2023 study published in the Journal of Organometallic Chemistry demonstrated its efficacy in catalyzing cross-coupling reactions, which are pivotal in pharmaceutical synthesis. The compound's stability under physiological conditions makes it a promising candidate for further exploration in drug development pipelines.
In the context of biomedical applications, Tri-n-octylchlorotin has shown notable antitumor activity in preclinical models. Research conducted by Liang et al. (2024) revealed that this compound induces apoptosis in cancer cells by disrupting mitochondrial function and generating reactive oxygen species (ROS). These findings were corroborated by in vitro assays using human breast cancer cell lines (MCF-7 and MDA-MB-231), where Tri-n-octylchlorotin exhibited IC50 values comparable to standard chemotherapeutic agents.
Despite its potential, the toxicity profile of Tri-n-octylchlorotin remains a critical area of investigation. A recent toxicological assessment published in Chemical Research in Toxicology (2024) emphasized the need for structural modifications to mitigate its hepatotoxic effects. Computational modeling studies have identified key molecular targets, such as cytochrome P450 enzymes, which could be leveraged to design safer analogs with retained bioactivity.
Looking ahead, the integration of Tri-n-octylchlorotin into nanomedicine platforms represents a promising frontier. A 2024 study in Advanced Materials showcased its incorporation into lipid-based nanoparticles for targeted drug delivery, achieving enhanced bioavailability and reduced off-target effects. Such innovations underscore the compound's adaptability and potential for translational research.
In conclusion, Tri-n-octylchlorotin (CAS: 2587-76-0) continues to be a molecule of interest in chemical biology and medicine. Its multifaceted applications—from catalysis to oncology—highlight the need for interdisciplinary collaboration to unlock its full potential. Future research should prioritize optimizing its safety profile and exploring novel delivery systems to facilitate clinical translation.
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