Cas no 25369-33-9 (7-chloro-2,3-dihydro-1H-indol-2-one)
7-Chloro-2,3-dihydro-1H-indol-2-one is a heterocyclic organic compound featuring a chloro-substituted indole scaffold with a ketone functional group at the 2-position. This structure serves as a versatile intermediate in pharmaceutical and agrochemical synthesis, particularly in the development of bioactive molecules. Its rigid indole core and electrophilic carbonyl group enable selective modifications, making it valuable for constructing complex frameworks. The chloro substituent enhances reactivity for further functionalization, while the dihydroindolone moiety offers stability under various reaction conditions. This compound is commonly utilized in medicinal chemistry research for the synthesis of potential therapeutic agents, including kinase inhibitors and CNS-active compounds. Its well-defined reactivity profile ensures consistent performance in multi-step synthetic routes.
25369-33-9 structure
Product Name:7-chloro-2,3-dihydro-1H-indol-2-one
CAS No:25369-33-9
MF:C8H6ClNO
MW:167.592340946198
MDL:MFCD06656001
CID:88585
PubChem ID:329761432
Update Time:2025-06-07
7-chloro-2,3-dihydro-1H-indol-2-one Chemical and Physical Properties
Names and Identifiers
-
- 7-Chloroindolin-2-one
- 7-Chloro-2-oxindole
- 5-Chloro-1,3-dihydro-2H-indol-2-one
- 7023 7-CHLOROINDOLIN-2-ONE
- 7-CHLOROOXINDOLE
- 7-chloro-1,3-dihydroindol-2-one
- 7-Chloro-1,3-dihydro-2H-indol-2-one
- 7-Chloro-2-oxyindole
- 2H-Indol-2-one, 7-chloro-1,3-dihydro-
- 7-chloro-2-oxo-1,2-dihydro-indole
- 7- Chlorooxindole
- PubChem8305
- 7-chlor-oindolin-2-one
- KSC911G1B
- IND016
- FPDLUAACCNVSQA-UHFFFAOYSA-N
- EBD50541
- BDBM50434117
- AB25436
- 7-chloro-2,3-dihydro-1H-indol-2-one
- CS-W008306
- 2H-Indol-2-one,7-chloro-1,3-dihydro-
- AC-22699
- AKOS005258603
- SY029305
- MFCD06656001
- SCHEMBL1162926
- AMY3655
- Q-102632
- FT-0656933
- 25369-33-9
- 7-Chloro-2-oxindole, 97%
- CHEMBL2381488
- 7-CHLORO-1,3-DIHYDRO-INDOL-2-ONE
- AS-32983
- DTXSID301293540
-
- MDL： MFCD06656001
- Inchi： 1S/C8H6ClNO/c9-6-3-1-2-5-4-7(11)10-8(5)6/h1-3H,4H2,(H,10,11)
- InChI Key： FPDLUAACCNVSQA-UHFFFAOYSA-N
- SMILES： ClC1=CC=CC2=C1NC(C2)=O
Computed Properties
- Exact Mass: 167.01400
- Monoisotopic Mass: 167.014
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 1
- Heavy Atom Count: 11
- Rotatable Bond Count: 0
- Complexity: 183
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 1.4
- Topological Polar Surface Area: 29.1
Experimental Properties
- Color/Form: White to yellowish brown solids, powders, crystals, crystalline powders, and / or bulk
- Density: 1.362
- Melting Point: 221-225?°C
- Boiling Point: 341°C at 760 mmHg
- Flash Point: 164.5 °C
- Refractive Index: 1.601
- PSA: 29.10000
- LogP: 1.97260
7-chloro-2,3-dihydro-1H-indol-2-one Security Information
-
Symbol:
- Signal Word：Warning
- Hazard Statement： H302,H319
- Warning Statement： P305+P351+P338
- Hazardous Material transportation number：NONH for all modes of transport
- WGK Germany：3
- Hazard Category Code： 22-52/53
- Safety Instruction： S61
-
Hazardous Material Identification：
- Risk Phrases：R22
- HazardClass：IRRITANT
- Storage Condition：Sealed in dry,Room Temperature
7-chloro-2,3-dihydro-1H-indol-2-one Customs Data
- HS CODE：2933790090
- Customs Data：
China Customs Code:
2933790090Overview:
2933790090 Other lactams. VAT:17.0% Tax refund rate:9.0% Regulatory conditions:nothing MFN tariff:9.0% general tariff:20.0%
Declaration elements:
Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date
Summary:
2933790090. other lactams. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:9.0%. General tariff:20.0%
7-chloro-2,3-dihydro-1H-indol-2-one Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Apollo Scientific | OR5622-5g |
7-Chloro-2-oxindole |
25369-33-9 | 98+% | 5g |
￡63.00 | 2025-02-20 | |
| Apollo Scientific | OR5622-25g |
7-Chloro-2-oxindole |
25369-33-9 | 98+% | 25g |
￡240.00 | 2025-02-20 | |
| SHANG HAI YI EN HUA XUE JI SHU Co., Ltd. | R012506-1g |
7-chloro-2,3-dihydro-1H-indol-2-one |
25369-33-9 | 97% | 1g |
￥127 | 2024-05-24 | |
| SHANG HAI YI EN HUA XUE JI SHU Co., Ltd. | R012506-5g |
7-chloro-2,3-dihydro-1H-indol-2-one |
25369-33-9 | 97% | 5g |
￥625 | 2024-05-24 | |
| TRC | B419385-10mg |
7-Chloroindolin-2-one |
25369-33-9 | 10mg |
$ 50.00 | 2022-06-07 | ||
| TRC | B419385-50mg |
7-Chloroindolin-2-one |
25369-33-9 | 50mg |
$ 65.00 | 2022-06-07 | ||
| TRC | B419385-100mg |
7-Chloroindolin-2-one |
25369-33-9 | 100mg |
$ 80.00 | 2022-06-07 | ||
| Matrix Scientific | 208479-5g |
7-Chlorooxindole |
25369-33-9 | 5g |
$363.00 | 2023-09-09 | ||
| Matrix Scientific | 208479-25g |
7-Chlorooxindole |
25369-33-9 | 25g |
$1452.00 | 2023-09-09 | ||
| SHANG HAI MAI KE LIN SHENG HUA Technology Co., Ltd. | C833256-5g |
7-Chloro-2-oxindole |
25369-33-9 | ≥97.0% | 5g |
772.00 | 2021-05-17 |
7-chloro-2,3-dihydro-1H-indol-2-one Suppliers
Amadis Chemical Company Limited
Gold Member
Audited Supplier
(CAS:25369-33-9)7-chloro-2,3-dihydro-1H-indol-2-one
Order Number:A5121
Stock Status:in Stock
Quantity:25g
Purity:99%
Pricing Information Last Updated:Monday, 2 September 2024 16:03
Price ($):312.0
Email:[email protected]
Suzhou Senfeida Chemical Co., Ltd
Gold Member
Audited Supplier
(CAS:25369-33-9)7-chloroindolin-2-one
Order Number:sfd15373
Stock Status:in Stock
Quantity:200kg
Purity:99.9%
Pricing Information Last Updated:Friday, 19 July 2024 14:37
Price ($):discuss personally
Email:[email protected]
7-chloro-2,3-dihydro-1H-indol-2-one Related Literature
-
Girish Singh Bisht,Akanksha M. Pandey,Moreshwar B. Chaudhari,Sandip G. Agalave,Abhishek Kanyal,Krishanpal Karmodiya,Boopathy Gnanaprakasam Org. Biomol. Chem. 2018 16 7223
-
Krishna Bahadur Somai Magar,T. N. Jebakumar Immanuel Edison,Yong Rok Lee Org. Biomol. Chem. 2016 14 7313
-
Xueji Ma,Xuemei Xie,Li Liu,Ran Xia,Tongyu Li,Hangxiang Wang Chem. Commun. 2018 54 1595
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