• 1. An arsenic trioxide nanoparticle prodrug (ATONP) potentiates a therapeutic effect on an aggressive hepatocellular carcinoma model via enhancement of intratumoral arsenic accumulation and disturbance of the tumor microenvironment?
  Xin Fu,Qing-rong Liang,Rong-guang Luo,Yan-shu Li,Xiao-ping Xiao,Lu-lu Yu,Wen-zhe Shan,Guang-qin Fan J. Mater. Chem. B, 2019,7, 3088-3099
• 2. An approach to the structure and vibrational analysis of cis- and trans-3-chlorostyrene through IR/Raman and INS spectroscopies and theoretical ab initio/DFT calculations?
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• 3. An aqueous ammonia sensor based on an inkjet-printed polyaniline nanoparticle-modified electrode
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• 4. Alternative donor substrates for inverting and retaining glycosyltransferases?
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• 5. An insight into the hybridization mechanism of hairpin DNA physically immobilized on chemically modified graphenes
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• Solvents and Organic Chemicals Organic Compounds Lipids and lipid-like molecules Fatty Acyls Fatty amides

Comprehensive Guide to 2-Bromo-3,3-dimethylbutanamide (CAS No. 25117-56-0): Properties, Applications, and Market Insights

2-Bromo-3,3-dimethylbutanamide (CAS No. 25117-56-0) is a specialized organic compound with a unique molecular structure, making it valuable in various chemical and pharmaceutical applications. This bromo-substituted amide is known for its versatility in synthetic chemistry, particularly in the development of intermediates for more complex molecules. Researchers and industry professionals often seek information on its synthesis methods, physical properties, and potential uses in drug discovery and material science.

The chemical structure of 2-bromo-3,3-dimethylbutanamide features a bromine atom attached to the second carbon of a butanamide backbone, with two methyl groups at the third carbon position. This arrangement contributes to its reactivity and stability under various conditions. The compound's molecular formula is C6H12BrNO, and it typically appears as a white to off-white crystalline solid. Its solubility in common organic solvents makes it particularly useful in laboratory settings and industrial processes.

One of the most frequently asked questions about CAS 25117-56-0 concerns its role in pharmaceutical research. Recent trends in drug development have increased interest in bromo-containing compounds as potential building blocks for new medications. The 2-bromo-3,3-dimethylbutanamide structure offers unique possibilities for creating novel therapeutic agents, particularly in areas such as central nervous system drugs and anti-inflammatory medications. Researchers are exploring its potential as a precursor in the synthesis of more complex bioactive molecules.

In the field of organic synthesis, 2-bromo-3,3-dimethylbutanamide serves as a valuable intermediate. Its bromine atom provides an excellent leaving group for nucleophilic substitution reactions, while the amide functionality offers additional sites for chemical modification. This dual reactivity makes the compound particularly useful for constructing complex molecular architectures. Recent publications have highlighted its application in the synthesis of heterocyclic compounds, which are crucial in many areas of medicinal chemistry and materials science.

The safety profile of 2-bromo-3,3-dimethylbutanamide is another important consideration for researchers and industrial users. While not classified as highly hazardous, proper laboratory handling procedures should always be followed when working with this compound. Standard precautions include using appropriate personal protective equipment (PPE) and working in well-ventilated areas. The compound's stability under normal conditions and storage requirements are frequently searched topics among chemical professionals.

Market trends for CAS 25117-56-0 show growing demand in both academic and industrial sectors. The increasing focus on custom synthesis and specialty chemicals has created new opportunities for suppliers of this compound. Pricing and availability of 2-bromo-3,3-dimethylbutanamide vary depending on purity levels and quantity requirements, with many suppliers offering both small-scale laboratory quantities and bulk industrial orders.

Analytical characterization of 2-bromo-3,3-dimethylbutanamide typically involves techniques such as nuclear magnetic resonance (NMR) spectroscopy, infrared spectroscopy (IR), and mass spectrometry (MS). These methods provide crucial information about the compound's purity and structural integrity. Researchers often search for detailed spectral data and analytical protocols when working with this material, making such information valuable for technical documentation.

Environmental considerations for 2-bromo-3,3-dimethylbutanamide are becoming increasingly important in chemical research and development. The compound's biodegradability and ecotoxicological profile are subjects of ongoing study. Current research focuses on developing greener synthesis methods and understanding the environmental fate of brominated organic compounds in general.

Future prospects for 2-bromo-3,3-dimethylbutanamide appear promising, particularly in the context of drug discovery and advanced materials development. As synthetic methodologies continue to advance, the compound's utility as a building block for more complex structures is likely to expand. The growing interest in structure-activity relationships and molecular design ensures continued relevance for this and similar brominated compounds in chemical research.

For researchers considering working with CAS 25117-56-0, it's important to consult the latest scientific literature and safety data sheets. The compound's reactivity patterns and potential applications are active areas of investigation, with new findings regularly appearing in chemical journals and patent literature. As with any specialized chemical, staying informed about the latest developments ensures optimal use in research and industrial applications.

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