Cas no 25021-48-1 (4-(2-PHENYL-1,3-THIAZOL-4-YL)ANILINE)

4-(2-Phenyl-1,3-thiazol-4-yl)aniline is a heterocyclic aromatic compound featuring a thiazole core linked to a phenyl group and an aniline moiety. This structure imparts versatility in organic synthesis, particularly in pharmaceutical and materials science applications. The presence of both electron-rich (aniline) and electron-deficient (thiazole) components enhances its utility as a building block for designing bioactive molecules or functional materials. Its well-defined reactivity allows for selective modifications, facilitating the development of derivatives with tailored properties. The compound's stability under standard conditions and compatibility with common synthetic methodologies make it a valuable intermediate for researchers in medicinal chemistry and material design.
4-(2-PHENYL-1,3-THIAZOL-4-YL)ANILINE structure
25021-48-1 structure
Product Name:4-(2-PHENYL-1,3-THIAZOL-4-YL)ANILINE
CAS No:25021-48-1
MF:C15H12N2S
MW:252.334181785583
MDL:MFCD04971846
CID:913412
PubChem ID:2049903
Update Time:2025-06-09

4-(2-PHENYL-1,3-THIAZOL-4-YL)ANILINE Chemical and Physical Properties

Names and Identifiers

    • 4-(2-PHENYL-1,3-THIAZOL-4-YL)ANILINE
    • 4-(2-Phenyl-thiazol-4-yl)-phenylamine
    • 2-Phenyl-4-(4'-aminophenyl)thiazol
    • 2-Phenyl-4-(4-amino-phenyl)-thiazol
    • 4-(2-phenyl-thiazol-4-yl)-aniline
    • AC1M1HBP
    • CTK8H8233
    • F1912-0013
    • SureCN2220170
    • SR-01000019062
    • DTXSID50365979
    • G62934
    • SR-01000019062-1
    • 25021-48-1
    • AKOS005207775
    • EN300-237778
    • 4-(2-phenylthiazol-4-yl)aniline
    • DB-112762
    • SCHEMBL2220170
    • MDL: MFCD04971846
    • Inchi: 1S/C15H12N2S/c16-13-8-6-11(7-9-13)14-10-18-15(17-14)12-4-2-1-3-5-12/h1-10H,16H2
    • InChI Key: IOPGDXLYFPHBLA-UHFFFAOYSA-N
    • SMILES: S1C=C(C2C=CC(=CC=2)N)N=C1C1C=CC=CC=1

Computed Properties

  • Exact Mass: 252.07226
  • Monoisotopic Mass: 252.07211956g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 18
  • Rotatable Bond Count: 2
  • Complexity: 257
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 3.6
  • Topological Polar Surface Area: 67.2?2

Experimental Properties

  • PSA: 38.91

4-(2-PHENYL-1,3-THIAZOL-4-YL)ANILINE Pricemore >>

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Additional information on 4-(2-PHENYL-1,3-THIAZOL-4-YL)ANILINE

Professional Introduction to 4-(2-PHENYL-1,3-THIAZOL-4-YL)ANILINE and CAS No. 25021-48-1

4-(2-PHENYL-1,3-THIAZOL-4-YL)ANILINE is a significant compound in the field of pharmaceutical chemistry, characterized by its unique structural and functional properties. This compound, identified by the CAS number CAS NO.25021-48-1, has garnered considerable attention due to its potential applications in drug development and medicinal chemistry. The molecular structure of this compound incorporates a thiazole ring fused with a phenyl group, linked to an aniline moiety, which contributes to its diverse chemical reactivity and biological activity.

The thiazole core is a heterocyclic aromatic compound that has been extensively studied for its pharmacological properties. It is known for its role in various biological processes and has been incorporated into numerous therapeutic agents. The presence of the phenyl group in 4-(2-PHENYL-1,3-THIAZOL-4-YL)ANILINE enhances its interaction with biological targets, making it a valuable scaffold for drug design. The aniline moiety further contributes to the compound's versatility, enabling various chemical modifications that can fine-tune its pharmacological profile.

In recent years, there has been a growing interest in developing novel therapeutic agents based on heterocyclic compounds. The structural features of 4-(2-PHENYL-1,3-THIAZOL-4-YL)ANILINE make it an attractive candidate for further investigation in this area. Current research focuses on exploring its potential as an intermediate in the synthesis of new drugs targeting various diseases, including cancer, infectious diseases, and neurological disorders.

The compound's unique chemical properties have also made it a subject of interest in materials science. Researchers are investigating its potential applications in the development of advanced materials with specific electronic and optical properties. The combination of the thiazole, phenyl, and aniline groups provides a rich framework for designing molecules with tailored functionalities.

The synthesis of 4-(2-PHENYL-1,3-THIAZOL-4-YL)ANILINE involves multi-step organic reactions that require precise control over reaction conditions. Advanced synthetic methodologies have been employed to optimize yield and purity, ensuring that the final product meets the stringent requirements for pharmaceutical applications. Techniques such as palladium-catalyzed cross-coupling reactions and transition-metal-catalyzed transformations have been particularly useful in constructing the complex molecular framework of this compound.

The pharmacological activity of 4-(2-PHENYL-1,3-THIAZOL-4-YL)ANILINE has been evaluated through various in vitro and in vivo studies. Preliminary results suggest that it exhibits promising biological effects that could be exploited for therapeutic purposes. Further research is ongoing to elucidate its mechanism of action and to identify potential side effects. These studies are crucial for determining the safety and efficacy of the compound before it can be considered for clinical use.

The integration of computational chemistry and molecular modeling techniques has played a pivotal role in understanding the interactions between 4-(2-PHENYL-1,3-THIAZOL-4-YL)ANILINE and biological targets. These tools have enabled researchers to predict the binding affinity and specificity of the compound, providing valuable insights into its pharmacological behavior. Such computational approaches are increasingly being used in drug discovery pipelines to accelerate the development of novel therapeutic agents.

The industrial significance of 4-(2-PHENYL-1,3-THIAZOL-4-YL)ANILINE cannot be overstated. Its synthesis and application represent a convergence of organic chemistry, medicinal chemistry, and materials science. As research continues to uncover new applications for this compound, it is likely to play an important role in the development of next-generation pharmaceuticals and advanced materials.

In conclusion, 4-(2-PHENYL-1,3-THIAZOL-4-YL)ANILINE is a multifaceted compound with significant potential in various scientific domains. Its unique structural features, coupled with its promising biological activity, make it a valuable asset in the quest for new therapeutic agents. As our understanding of its properties continues to grow, so too will its applications across different fields of science and technology.

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