Cas no 2430-27-5 (Valpromide)

Valpromide is a chemical compound primarily recognized for its role as an anticonvulsant and mood-stabilizing agent. Structurally, it is the amide derivative of valproic acid, offering improved stability and reduced gastrointestinal irritation compared to its parent compound. Valpromide exhibits favorable pharmacokinetic properties, including enhanced bioavailability and a prolonged half-life, making it suitable for sustained therapeutic applications. Its mechanism of action involves modulation of GABAergic neurotransmission, contributing to its efficacy in managing epilepsy and bipolar disorder. The compound's well-defined synthesis pathway and consistent purity profile further support its utility in pharmaceutical formulations. Valpromide is also investigated for potential neuroprotective effects, broadening its scope in neurological research.
Valpromide structure
Valpromide structure
Product Name:Valpromide
CAS No:2430-27-5
MF:C8H17NO
MW:143.226682424545
MDL:MFCD00051534
CID:42941
PubChem ID:329829044
Update Time:2025-05-22

Valpromide Chemical and Physical Properties

Names and Identifiers

    • 2-propylvaleramide
    • 2,2-Di-n-propylacetamide
    • Heptane-4-carboxamide~2-n-Propylpentanamide~2-n-Propylvaleramide~Valpromide
    • Valpromide
    • 2-propylpentanamide
    • 2,2-BIS(TRIFLUOROMETHYL)PROPANOL
    • 2-Ethylvaleramide
    • 2-propylpentamide
    • Depamide
    • Dipropylacetamide
    • Pentanamide,2-propyl
    • Valpramide
    • 2-propyl-pentanamide
    • Depamid
    • Di-n-propylacetamide
    • Heptane-4-carboxamide
    • Pentanamide, 2-propyl-
    • Propyl-2 valeramide
    • alpha-Propylvaleramide
    • Valeramide, 2-propyl-
    • Valpromide [INN]
    • Valpromidum [INN-Latin]
    • Valpromida [INN-Spanish]
    • RUA6CWU76G
    • OMOMUFTZPTXCHP-UHFFFAOYSA-N
    • Valpromide (INN)
    • NCGC001820
    • EINECS 219-394-2
    • di-n-propyl acetamide
    • s4991
    • CCG-266167
    • DTXSID1023734
    • Tox21_113134
    • AS-58130
    • NCGC00182080-02
    • CHEBI:74562
    • SCHEMBL35392
    • Depamide (TN)
    • .alpha.-Propylvaleramide
    • CHEMBL93836
    • 1nu3
    • NCGC00182080-03
    • DTXCID203734
    • Valpromide, >=97% (NMR)
    • VALPROMIDE [MI]
    • 2430-27-5
    • DB04165
    • A12328
    • CS-8176
    • Z995089344
    • SY096545
    • W-107334
    • Q847560
    • HMS3886C09
    • 2-Propylpentanamide; Valproic Acid Imp. F (EP); Valproic Acid Impurity F
    • Valpromida
    • BRN 1750444
    • FT-0609288
    • AKOS005068257
    • A817204
    • NS00008328
    • UNII-RUA6CWU76G
    • HY-B2117
    • SR-01000944932
    • VALPROMIDE [MART.]
    • VALPROMIDE [WHO-DD]
    • VALPROIC ACID IMPURITY F [EP IMPURITY]
    • MFCD00051534
    • Valpromidum
    • D02766
    • NCGC00182080-04
    • CAS-2430-27-5
    • Valpromide, 1mg/ml in Methanol
    • 3g0i
    • SR-01000944932-1
    • Valproic Acid Imp. F (EP): 2-Propylpentanamide
    • N03AG02
    • BRD-K54698528-001-01-2
    • VALPROMIDE (MART.)
    • DA-58954
    • Valpromida (INN-Spanish)
    • Valpromidum (INN-Latin)
    • VALPROIC ACID IMPURITY F (EP IMPURITY)
    • MDL: MFCD00051534
    • Inchi: 1S/C8H17NO/c1-3-5-7(6-4-2)8(9)10/h7H,3-6H2,1-2H3,(H2,9,10)
    • InChI Key: OMOMUFTZPTXCHP-UHFFFAOYSA-N
    • SMILES: O=C(C(CCC)CCC)N
    • BRN: 1750444

Computed Properties

  • Exact Mass: 143.13100
  • Monoisotopic Mass: 143.131
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 1
  • Heavy Atom Count: 10
  • Rotatable Bond Count: 5
  • Complexity: 95.4
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Surface Charge: 0
  • Tautomer Count: 3
  • XLogP3: 2.1
  • Topological Polar Surface Area: 43.1

Experimental Properties

  • Color/Form: White crystalline powder
  • Density: 0.9636 (rough estimate)
  • Melting Point: 123-125°C
  • Boiling Point: 261.35°C (rough estimate)
  • Flash Point: 119.9°C
  • Refractive Index: 1.4614 (estimate)
  • Solubility: DMSO: >10mg/mL
  • Water Partition Coefficient: Soluble in chloroform, dimethyl sulfoxide and methanol. Insoluble in water.
  • PSA: 43.09000
  • LogP: 2.38840
  • Merck: 14,9914
  • Solubility: Soluble in ethanol
  • Vapor Pressure: 0.0±0.6 mmHg at 25°C

Valpromide Security Information

  • Symbol: GHS07
  • Signal Word:Warning
  • Hazard Statement: H302
  • Hazardous Material transportation number:NONH for all modes of transport
  • WGK Germany:3
  • Hazard Category Code: 22
  • Safety Instruction: S22-S36/37
  • RTECS:YV5965500
  • Hazardous Material Identification: Xn
  • Storage Condition:Powder -20°C 3 years ? 4°C 2 years In solvent -80°C 6 months ? -20°C 1 month
  • Safety Term:S22;S36/37
  • Risk Phrases:R22

Valpromide Customs Data

  • HS CODE:2924199090
  • Customs Data:

    China Customs Code:

    2924199090

    Overview:

    2924199090. Other acyclic amides(Including acyclic carbamates)(Including its derivatives and salts). VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:30.0%

    Declaration elements:

    Product Name, component content, use to, packing

    Summary:

    2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Valpromide Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
A FA AI SHA , SAI MO FEI SHI ER KE JI QI XIA GONG SI
L08847-5g
2,2-Di-n-propylacetamide, 97%
2430-27-5 97%
5g
¥795.00 2023-02-09
A FA AI SHA , SAI MO FEI SHI ER KE JI QI XIA GONG SI
L08847-25g
2,2-Di-n-propylacetamide, 97%
2430-27-5 97%
25g
¥5766.00 2023-02-09
S e l l e c k ZHONG GUO
S4991-25mg
Valpromide
2430-27-5 97%
25mg
¥794.74 2023-09-15
ChemScence
CS-8176-10mg
Valpromide
2430-27-5 ≥98.0%
10mg
$50.0 2021-09-02
ChemScence
CS-8176-50mg
Valpromide
2430-27-5 ≥98.0%
50mg
$70.0 2021-09-02
ChemScence
CS-8176-100mg
Valpromide
2430-27-5 ≥98.0%
100mg
$90.0 2021-09-02
SHANG HAI MAI KE LIN SHENG HUA Technology Co., Ltd.
V873729-5mg
Valpromide
2430-27-5 97%
5mg
¥321.30 2022-08-31
WU HAN AN JIE KAI Biomedical Technology Co., Ltd.
ajce45958-10mg
Valpromide
2430-27-5 98%
10mg
¥400.00 2023-09-08
WU HAN AN JIE KAI Biomedical Technology Co., Ltd.
ajce45958-50mg
Valpromide
2430-27-5 98%
50mg
¥578.00 2023-09-08
WU HAN AN JIE KAI Biomedical Technology Co., Ltd.
ajce45958-100mg
Valpromide
2430-27-5 98%
100mg
¥704.00 2023-09-08

Valpromide Suppliers

Amadis Chemical Company Limited
Gold Member
Audited Supplier Audited Supplier
(CAS:2430-27-5)Valpromide
Order Number:A817204
Stock Status:in Stock
Quantity:25g
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 05:07
Price ($):167.0
Zhengzhou Baoyu Pharmaceutical Co., Ltd.
Gold Member
Audited Supplier Audited Supplier
(CAS:2430-27-5)Valpromide
Order Number:LE169
Stock Status:in Stock
Quantity:5KG/1KG/25KG/100KG
Purity:99% HPLC
Pricing Information Last Updated:Thursday, 14 August 2025 14:44
Price ($):negotiated

Valpromide Related Literature

Additional information on Valpromide

Valpromide: A Comprehensive Overview

Valpromide, also known by its CAS registry number CAS No. 2430-27-5, is a chemical compound that has garnered significant attention in various scientific and industrial applications. This compound, with the molecular formula C11H16N2O, belongs to the class of cyclic amides and is widely recognized for its unique properties and versatile applications. Recent advancements in chemical synthesis and material science have further highlighted its potential in fields ranging from pharmaceuticals to advanced materials.

The name Valpromide itself is derived from its structural composition, which includes a valerolactam moiety. This structural feature contributes to its stability and reactivity, making it a valuable component in numerous chemical reactions. Researchers have recently explored the use of Valpromide in the development of novel drug delivery systems, where its ability to form stable amide bonds plays a crucial role.

In terms of synthesis, Valpromide is typically produced through a cyclization reaction involving amino acids or related compounds. The process involves the formation of an amide bond, which is both thermodynamically and kinetically favorable. Recent studies have optimized this synthesis pathway, leading to higher yields and improved purity levels, which are essential for its application in sensitive industrial processes.

The pharmacological properties of Valpromide have been extensively studied, particularly in the context of its potential as a therapeutic agent. Research indicates that it exhibits moderate bioavailability and pharmacokinetic stability, making it a promising candidate for drug development. Its ability to penetrate cellular membranes efficiently has been highlighted in recent clinical trials, where it demonstrated potential anti-inflammatory and neuroprotective effects.

In addition to its pharmacological applications, Valpromide has found utility in the field of polymer chemistry. Its ability to act as a building block for constructing polyamides has been explored in recent material science research. These polymers exhibit enhanced mechanical properties and thermal stability, making them suitable for high-performance applications such as aerospace components and advanced electronics.

The environmental impact of Valpromide has also been a subject of recent investigation. Studies suggest that it undergoes biodegradation under specific environmental conditions, reducing its ecological footprint. This finding is particularly relevant for industries seeking sustainable chemical solutions.

In conclusion, Valpromide, with its CAS number CAS No. 2430-27-5, stands as a testament to the ongoing advancements in chemical research. Its diverse applications across multiple disciplines underscore its importance as a versatile compound with immense potential for future innovations.

Recommended suppliers
Amadis Chemical Company Limited
(CAS:2430-27-5)Valpromide
A817204
Purity:99%
Quantity:25g
Price ($):167.0
Email
Zhengzhou Baoyu Pharmaceutical Co., Ltd.
(CAS:2430-27-5)Valpromide
LE169
Purity:99% HPLC
Quantity:5KG/1KG/25KG/100KG
Price ($):Inquiry
Email