• 1. Evolution of hierarchical porous structures in supramolecular guest–host hydrogels?
  Christopher B. Rodell,Christopher B. Highley,Minna H. Chen,Neville N. Dusaj,Chao Wang,Lin Han,Jason A. Burdick Soft Matter, 2016,12, 7839-7847
• 2. Estimates of hydride ion stability in condensed systems: energy of formation and solvation in aqueous and polar-organic solvents
  Craig A. Kelly,David R. Rosseinsky Phys. Chem. Chem. Phys., 2001,3, 2086-2090
• 3. Exchangeability of amino acid residues with similar physicochemical properties in coiled-coil interactions?
  Guiying Zhang,Maosheng Cheng,Yanni Li,Keliang Liu,Lifeng Cai Chem. Commun., 2013,49, 11086-11088
• 4. Excess electrons in lithium–ethylamine solutions—density, electrical conductivity and EPR studies
  Phys. Chem. Chem. Phys., 1999,1, 3561-3565
• 5. Elusive 2-aminofuran Diels–Alder substrates for a straightforward synthesis of polysubstituted anilines?
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• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Phenylpropenes

Benzonitrile, 2-(1-methylethenyl)- (CAS No. 23877-63-6)

Benzonitrile, 2-(1-methylethenyl)-, also known by its CAS registry number CAS No. 23877-63-6, is a versatile organic compound with significant applications in various fields of chemistry and materials science. This compound, characterized by its structure containing a benzonitrile group and a substituted vinyl group, has garnered attention due to its unique chemical properties and potential for further functionalization. Recent studies have highlighted its role in the synthesis of advanced materials, including polymers and pharmaceutical intermediates.

The synthesis of Benzonitrile, 2-(1-methylethenyl)- typically involves the use of palladium-catalyzed coupling reactions or other transition metal-mediated processes. These methods have been optimized in recent years to enhance yield and selectivity, making the compound more accessible for large-scale production. Researchers have also explored alternative routes using biocatalysts, which offer an environmentally friendly approach to synthesizing this compound.

In terms of applications, Benzonitrile, 2-(1-methylethenyl)- serves as a valuable intermediate in the production of specialty chemicals. Its ability to undergo various functional group transformations makes it a key building block in organic synthesis. For instance, it can be converted into amides, esters, or other nitrile derivatives through simple chemical reactions. Recent advancements in catalytic chemistry have further expanded its utility in the development of bioactive molecules and agrochemicals.

The chemical stability of Benzonitrile, 2-(1-methylethenyl)- under diverse reaction conditions has been extensively studied. It exhibits good thermal stability and is resistant to oxidation under mild conditions, which are advantageous for its use in high-temperature applications or long-term storage. However, exposure to strong oxidizing agents or extreme conditions may lead to decomposition or side reactions.

From an environmental standpoint, the ecological impact of Benzonitrile, 2-(1-methylethenyl)- has been a topic of recent research interest. Studies indicate that it is not inherently toxic at typical exposure levels but may undergo biodegradation under specific environmental conditions. Regulatory agencies have established guidelines for safe handling and disposal to minimize its environmental footprint.

In conclusion, Benzonitrile, 2-(1-methylethenyl)- (CAS No. 23877-63-6) remains a pivotal compound in modern organic chemistry due to its structural versatility and wide-ranging applications. Ongoing research continues to uncover new avenues for its utilization in both industrial and academic settings.

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