Cas no 22187-96-8 (5-methoxypyridine-2-carbaldehyde)

5-Methoxypyridine-2-carbaldehyde is a versatile heterocyclic aldehyde used as a key intermediate in organic synthesis and pharmaceutical research. Its pyridine core, functionalized with a methoxy group at the 5-position and an aldehyde at the 2-position, offers selective reactivity for constructing complex molecules, particularly in medicinal chemistry and agrochemical applications. The compound's electron-rich aromatic system enhances its utility in nucleophilic addition and condensation reactions, facilitating the synthesis of derivatives such as Schiff bases or heterocyclic scaffolds. Its well-defined structure and stability under standard conditions make it a reliable building block for developing bioactive compounds, catalysts, and functional materials.

5-methoxypyridine-2-carbaldehyde structure

22187-96-8 structure

Product Name:5-methoxypyridine-2-carbaldehyde

CAS No:22187-96-8

MF:C₇H₇NO₂

MW:137.135981798172

MDL:MFCD08234867

CID:51985

PubChem ID:23450640

Update Time:2025-05-25

5-methoxypyridine-2-carbaldehyde Chemical and Physical Properties

Names and Identifiers

- 5-Methoxypicolinaldehyde
- 5-methoxypyridine-2-carbaldehyde
- 5-Methoxypyridine-2-carboxaldehyde
- 2-FORMYL-5-METHOXYPYRIDINE
- 2-Pyridinecarboxaldehyde,5-methoxy
- 5-methoxy-2-pyridinecarbaldehyde
- 5-methoxy-2-pyridinecarboxaldehyde
- 5-methoxy-pyridine-2-carbaldehyde
- PubChem24092
- CTYUCLSCBVSTAA-UHFFFAOYSA-N
- EBD39117
- 2-Pyridinecarboxaldehyde,5-methoxy-
- 2-Pyridinecarboxaldehyde, 5-methoxy-
- PB17495
- AM84791
- RP20350
- 22187-96-8
- DTXSID30634276
- SY039034
- CS-W005343
- J-509538
- AKOS006287192
- AC-24596
- Z1198176556
- SCHEMBL967531
- AS-18768
- MFCD08234867
- SCHEMBL733531
- FT-0630178
- EN300-134886
- DB-013037
- MDL： MFCD08234867
- Inchi： 1S/C7H7NO2/c1-10-7-3-2-6(5-9)8-4-7/h2-5H,1H3
- InChI Key： CTYUCLSCBVSTAA-UHFFFAOYSA-N
- SMILES： O(C)C1=CN=C(C=O)C=C1

Computed Properties

Exact Mass: 137.04800
Monoisotopic Mass: 137.048
Isotope Atom Count: 0
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 3
Heavy Atom Count: 10
Rotatable Bond Count: 2
Complexity: 116
Covalently-Bonded Unit Count: 1
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count : 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Topological Polar Surface Area: 39.2
XLogP3: 0.6

Experimental Properties

Color/Form: Pale-yellow to Yellow-brown Solid
Density: 1.159
Melting Point: 35°C
Boiling Point: 248.3℃ at 760 mmHg
Flash Point: 248.375 °C at 760 mmHg
Refractive Index: 1.551
PSA: 39.19000
LogP: 0.90270

5-methoxypyridine-2-carbaldehyde Security Information

Signal Word：Warning
Hazard Statement： H315; H319; H335
Warning Statement： P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501
Safety Instruction： H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body
Storage Condition：Store long-term at 2-8°C

5-methoxypyridine-2-carbaldehyde Customs Data

HS CODE：2933399090
Customs Data：

China Customs Code:
2933399090

Overview:

2933399090. Other compounds with non fused pyridine rings in structure. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

Declaration elements:

Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date

Summary:

2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

5-methoxypyridine-2-carbaldehyde Pricemore >>

Related Categories	No.	Product Name	Cas No.	Purity	Specification	Price	update time
SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd.	M182921-1g	5-methoxypyridine-2-carbaldehyde	22187-96-8	97%	1g	￥571.90	2023-09-01
SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd.	M182921-100mg	5-methoxypyridine-2-carbaldehyde	22187-96-8	97%	100mg	￥131.90	2023-09-01
SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd.	M182921-5g	5-methoxypyridine-2-carbaldehyde	22187-96-8	97%	5g	￥2004.90	2023-09-01
SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd.	M182921-250mg	5-methoxypyridine-2-carbaldehyde	22187-96-8	97%	250mg	￥207.90	2023-09-01
SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd.	M182921-50mg	5-methoxypyridine-2-carbaldehyde	22187-96-8	97%	50mg	￥80.90	2023-09-01
AstaTech	61667-0.25/G	2-FORMYL-5-METHOXYPYRIDINE	22187-96-8	95%	0.25g	$55	2023-09-16
AstaTech	61667-1/G	2-FORMYL-5-METHOXYPYRIDINE	22187-96-8	95%	1g	$135	2023-09-16
AstaTech	61667-5/G	2-FORMYL-5-METHOXYPYRIDINE	22187-96-8	95%	5g	$405	2023-09-16
Fluorochem	050083-250mg	5-Methoxypicolinaldehyde	22187-96-8	95%	250mg	￡49.00	2022-03-01
Fluorochem	050083-1g	5-Methoxypicolinaldehyde	22187-96-8	95%	1g	￡123.00	2022-03-01

5-methoxypyridine-2-carbaldehyde Suppliers

Suzhou Senfeida Chemical Co., Ltd

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Audited Supplier

(CAS:22187-96-8)5-METHOXYPICOLINALDEHYDE

Order Number:sfd16985

Stock Status:in Stock

Quantity:200kg

Purity:99.9%

Pricing Information Last Updated:Friday, 19 July 2024 14:37

Price ($):discuss personally

Email:[email protected]

Product Official Link

Amadis Chemical Company Limited

Gold Member

Audited Supplier

(CAS:22187-96-8)5-methoxypyridine-2-carbaldehyde

Order Number:A848686

Stock Status:in Stock

Quantity:25g

Purity:99%

Pricing Information Last Updated:Friday, 30 August 2024 07:21

Price ($):420.0

Email:[email protected]

Product Official Link

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Related Categories

Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Pyridines and derivatives Pyridine carboxaldehydes

Additional information on 5-methoxypyridine-2-carbaldehyde

5-Methoxypyridine-2-Carbaldehyde: A Comprehensive Overview

5-Methoxypyridine-2-carbaldehyde (CAS No. 22187-96-8) is a fascinating organic compound with a unique structure and diverse applications. This compound, also referred to as 5-methoxypyridine-2-carbaldehyde, belongs to the class of aromatic aldehydes and has garnered significant attention in recent years due to its potential in various fields, including pharmaceuticals, agrochemicals, and materials science.

The molecular structure of 5-methoxypyridine-2-carbaldehyde consists of a pyridine ring substituted with a methoxy group at the 5-position and an aldehyde group at the 2-position. This arrangement imparts the compound with distinctive electronic and steric properties, making it highly versatile for chemical modifications. The pyridine ring serves as a rigid framework, while the aldehyde group introduces reactivity, enabling participation in various condensation reactions such as aldol and Perkin reactions.

Recent studies have highlighted the importance of 5-methoxypyridine-2-carbaldehyde in drug discovery. Researchers have explored its role as a building block for constructing bioactive molecules. For instance, its ability to form enamine derivatives has been exploited to develop potential antitumor agents. The compound's methoxy group also plays a crucial role in modulating the pharmacokinetic properties of derived drugs, enhancing their solubility and bioavailability.

In the realm of agrochemicals, 5-methoxypyridine-2-carbaldehyde has shown promise as a precursor for herbicides and insecticides. Its reactivity allows for the synthesis of compounds with enhanced pesticidal activity. For example, derivatives of this compound have demonstrated efficacy against various agricultural pests without causing significant harm to non-target organisms.

The synthesis of 5-methoxypyridine-2-carbaldehyde typically involves multi-step processes that include nucleophilic substitution and oxidation reactions. Recent advancements in catalytic methods have streamlined its production, making it more cost-effective and environmentally friendly. The use of transition metal catalysts has significantly improved the yield and purity of the compound, aligning with current trends toward sustainable chemistry.

From a materials science perspective, 5-methoxypyridine-2-carbaldehyde has been investigated for its potential in organic electronics. Its conjugated system enables efficient charge transport properties, making it a candidate for use in organic semiconductors and light-emitting diodes (OLEDs). Researchers are actively exploring ways to incorporate this compound into next-generation electronic devices to enhance their performance.

In conclusion, 5-methoxypyridine-2-carbaldehyde (CAS No. 22187-96-8) is a multifaceted compound with applications spanning multiple disciplines. Its unique structure and reactivity make it an invaluable tool in modern chemistry. As research continues to uncover new potentials for this compound, it is poised to play an even greater role in advancing scientific and technological frontiers.

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