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• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Diazines Halopyrimidines
• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Diazines Pyrimidines and pyrimidine derivatives Halopyrimidines

Introduction to CAS No 22177-94-2: 2-[(6-Chloropyrimidin-4-Yl)Amino]Ethan-1-Ol

The compound CAS No 22177-94-2, also known as 2-[(6-chloropyrimidin-4-yl)amino]ethan-1-ol, is a versatile organic compound with significant applications in the fields of pharmaceuticals, agrochemicals, and materials science. This compound has garnered attention due to its unique chemical properties and its potential in various research and industrial settings. In this article, we will delve into the structural characteristics, synthesis methods, and recent advancements in the utilization of this compound.

Chemical Structure and Synthesis

CAS No 22177-94-2 features a pyrimidine ring substituted with a chlorine atom at the 6-position and an aminoethyl alcohol group at the 4-position. The structure of this compound is characterized by its pyrimidine core, which is a six-membered ring consisting of two nitrogen atoms. The presence of the chlorine substituent introduces electronic effects that influence the reactivity and stability of the molecule. The aminoethyl alcohol group adds hydrophilic properties, making it suitable for applications requiring both hydrophobic and hydrophilic interactions.

The synthesis of CAS No 22177-94-2 typically involves multi-step reactions, including nucleophilic substitutions, reductions, and coupling reactions. Recent studies have focused on optimizing these processes to enhance yield and reduce costs. For instance, researchers have explored the use of microwave-assisted synthesis to accelerate reaction times while maintaining product purity.

Physical Properties and Stability

CAS No 22177-94-2 exhibits a melting point of approximately 150°C and a boiling point around 350°C under standard conditions. The compound is sparingly soluble in water but dissolves readily in organic solvents such as dichloromethane and acetonitrile. Its stability is influenced by environmental factors such as temperature and pH levels. Recent research has shown that the compound remains stable under neutral to mildly basic conditions but undergoes degradation in strongly acidic environments.

Applications in Pharmaceuticals

The pharmaceutical industry has shown considerable interest in CAS No 22177-94-2 due to its potential as an intermediate in drug development. The compound serves as a building block for synthesizing bioactive molecules with anti-inflammatory, antiviral, and anticancer properties. For example, studies have demonstrated that derivatives of this compound exhibit potent inhibitory activity against enzymes involved in inflammatory pathways, making them promising candidates for treating conditions such as arthritis.

In addition, CAS No 22177-94-2 has been explored for its role in developing antiviral agents targeting RNA viruses. Recent research highlights its ability to inhibit viral replication by interfering with essential viral proteins, offering a novel approach to combating emerging viral threats.

Role in Agrochemicals

Beyond pharmaceuticals, CAS No 22177-94} has found applications in agrochemicals, particularly as an intermediate in the synthesis of pesticides and herbicides. Its ability to modulate enzyme activity makes it valuable for developing compounds that target specific pests or weeds without harming crops. Recent advancements have focused on enhancing the selectivity of these compounds to minimize environmental impact.

Materials Science Applications

In materials science, CAS No 22177} has been utilized as a precursor for synthesizing advanced materials such as polymers and coordination complexes. Its functional groups enable it to act as a versatile linker or cross-linker in polymer networks, contributing to improved mechanical and thermal properties. Researchers have also explored its use in creating metalloorganic frameworks (MOFs), which have applications in gas storage and catalysis.

Recent Research Highlights

Recent studies have shed light on novel aspects of CAS No 2} chemistry. For instance, investigations into its electrochemical properties have revealed its potential as an electrode material in energy storage devices such as supercapacitors. Additionally, research into its photochemical behavior has uncovered applications in light-responsive materials for use in optoelectronics.

Another area of active research involves the use of CAS No} in click chemistry reactions. These reactions enable rapid assembly of complex molecules with high efficiency, opening new avenues for drug discovery and materials synthesis.

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• 872511-30-3(6-chloro-N-ethylpyrimidin-4-amine)
• 22177-92-0(4-(6-Chloropyrimidin-4-yl)morpholine)
• 2846-77-7(2-(2-Amino-6-chloropyrimidin-4-yl)aminoethanol)
• 503610-76-2(6-chloro-N-(2-methoxyethyl)pyrimidin-4-amine)
• 1219963-83-3(2-(6-Chloro-4-pyrimidinyl)amino-2-methyl-1-propanol)
• 1220036-27-0(2-(4-(6-chloropyrimidin-4-yl)piperazin-1-yl)ethan-1-ol)
• 22177-97-5(2-(6-Chloro-2-methyl-4-pyrimidinyl)amino-1-ethanol)
• 879609-73-1(2,6-Dichloro-N-(2-methoxyethyl)pyrimidin-4-amine)
• 89728-42-7(6-Chloro-N-ethyl-2-methylpyrimidin-4-amine)