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• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Benzene and substituted derivatives
• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives

Compound CAS No. 22078-90-6: (5-Phenylfuran-2-yl)methanol

The compound with CAS No. 22078-90-6, commonly referred to as (5-Phenylfuran-2-yl)methanol, is a fascinating organic molecule that has garnered significant attention in the fields of organic chemistry, pharmacology, and material science. This compound is characterized by its unique structure, which combines a phenyl group attached to a furan ring, further substituted with a methanol group at the 5-position of the furan moiety. The molecule's structure not only imparts it with interesting physical and chemical properties but also makes it a valuable precursor for various synthetic applications.

Chemical Structure and Properties

(5-Phenylfuran-2-yl)methanol consists of a furan ring, a five-membered aromatic heterocycle containing one oxygen atom. The furan ring is substituted at the 5-position with a phenyl group, which introduces aromaticity and enhances the molecule's stability. Additionally, the methanol group (-CH?OH) attached to the 2-position of the furan ring introduces hydroxymethyl functionality, making this compound both hydrophilic and capable of participating in hydrogen bonding. This combination of structural features gives rise to unique chemical properties, including moderate solubility in polar solvents and reactivity towards various nucleophilic and electrophilic substitutions.

Synthesis and Applications

The synthesis of (5-Phenylfuran-2-yl)methanol can be achieved through several routes, including nucleophilic aromatic substitution, coupling reactions, and oxidation processes. Recent advancements in catalytic methods have enabled more efficient and selective syntheses of this compound, reducing production costs and environmental impact. The compound finds applications in diverse areas such as fragrance formulation, pharmaceutical intermediates, and as building blocks for advanced materials.

In the fragrance industry, (5-Phenylfuran-2-yl)methanol is valued for its pleasant floral aroma, making it a key ingredient in perfumes and personal care products. Its ability to impart subtle yet complex olfactory notes has made it indispensable in creating high-end fragrances. Furthermore, its role as an intermediate in drug discovery has been significant. Researchers have explored its potential as a lead compound for developing novel therapeutic agents targeting various diseases.

Recent Research Findings

Recent studies have shed light on the biological activities of (5-Phenylfuran-2-yl)methanol. For instance, investigations into its antioxidant properties have revealed its potential as a natural preservative in food and cosmetics. Additionally, research into its interaction with cellular receptors has opened avenues for its use in designing bioactive molecules with specific pharmacological profiles.

In material science, (5-Phenylfuran-2-yl)methanol has been employed as a monomer in polymer synthesis due to its ability to form stable covalent bonds under specific reaction conditions. This has led to the development of novel polymeric materials with tailored mechanical and thermal properties.

Conclusion

(5-(Phenylfuran)-methyl alcohol), or CAS No. 22078906, stands out as a versatile compound with a wide range of applications across multiple disciplines. Its unique chemical structure endows it with properties that make it invaluable in both industrial and academic settings. As research continues to uncover new facets of this molecule's potential, it is poised to play an even more significant role in driving innovation across various sectors.

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• 33342-28-8(5-(4-Bromophenyl)-2-furylmethanol)
• 955-83-9(2,5-Diphenylfuran)
• 773872-95-0(Benzenemethanol,4-(5-methyl-2-furanyl)-)
• 54146-51-9(5-(4-Aminophenyl)-2-furylmethanol)
• 33342-29-9(5-(4-Chlorophenyl)-2-furylmethanol)
• 764710-29-4(5-(3-aminophenyl)-2-furylmethanol)
• 17920-85-3(4-(2-Furyl)phenylmethanol)
• 53782-69-7(4-(5-hydroxymethyl-furan-2-yl)-benzoic acid)