Cas no 220497-88-1 (1,2-Cyclopentanediol,3-amino-5-(hydroxymethyl)-, hydrochloride (1:1), (1S,2R,3S,5S)-)

1,2-Cyclopentanediol,3-amino-5-(hydroxymethyl)-, hydrochloride (1:1), (1S,2R,3S,5S)- structure
220497-88-1 structure
Product Name:1,2-Cyclopentanediol,3-amino-5-(hydroxymethyl)-, hydrochloride (1:1), (1S,2R,3S,5S)-
CAS No:220497-88-1
MF:C6H13NO3
MW:147.172322034836
CID:282837
PubChem ID:11887845
Update Time:2025-11-01

1,2-Cyclopentanediol,3-amino-5-(hydroxymethyl)-, hydrochloride (1:1), (1S,2R,3S,5S)- Chemical and Physical Properties

Names and Identifiers

    • 1,2-Cyclopentanediol,3-amino-5-(hydroxymethyl)-, hydrochloride (1:1), (1S,2R,3S,5S)-
    • (1S,2R,3S,4S)-2,3-Dihydroxy-4-(hydroxymethyl)-1-aminocyclopentane hydrochloride
    • 106707-52-2
    • (1S,2R,3S,5S)-3-Amino-5-(hydroxymethyl)-1,2-cyclopentanediol
    • DTXSID501186676
    • FHNKBDPGQXLKRW-OMMKOOBNSA-N
    • SCHEMBL1368473
    • AKOS006338152
    • 220497-88-1
    • (1S,2R,3S,5S)-3-Amino-5-hydroxymethyl-cyclopentane-1,2-diol
    • (1S,2R,3S,5S)-3-amino-5-(hydroxymethyl)cyclopentane-1,2-diol
    • Inchi: 1S/C6H13NO3/c7-4-1-3(2-8)5(9)6(4)10/h3-6,8-10H,1-2,7H2/t3-,4-,5-,6+/m0/s1
    • InChI Key: FHNKBDPGQXLKRW-OMMKOOBNSA-N
    • SMILES: O[C@@H]1[C@@H]([C@H](C[C@H]1CO)N)O

Computed Properties

  • Exact Mass: 147.09000
  • Monoisotopic Mass: 147.09
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 4
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 10
  • Rotatable Bond Count: 1
  • Complexity: 120
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 4
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 86.7A^2
  • XLogP3: -1.6

Experimental Properties

  • Density: 1.2361 (rough estimate)
  • Melting Point: 125.4 °C
  • Boiling Point: 300.9°Cat760mmHg
  • Flash Point: 135.8°C
  • Refractive Index: 1.5810 (estimate)
  • PSA: 86.71000
  • LogP: -1.25200

1,2-Cyclopentanediol,3-amino-5-(hydroxymethyl)-, hydrochloride (1:1), (1S,2R,3S,5S)- Security Information

  • Hazard Category Code: 36/37/38
  • Safety Instruction: S26-S37/39
  • Hazardous Material Identification: Xi
  • Risk Phrases:R36/37/38
  • Safety Term:S26;S37/39

1,2-Cyclopentanediol,3-amino-5-(hydroxymethyl)-, hydrochloride (1:1), (1S,2R,3S,5S)- Pricemore >>

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Additional information on 1,2-Cyclopentanediol,3-amino-5-(hydroxymethyl)-, hydrochloride (1:1), (1S,2R,3S,5S)-

Comprehensive Guide to 1,2-Cyclopentanediol,3-amino-5-(hydroxymethyl)-, hydrochloride (1:1), (1S,2R,3S,5S)- (CAS No. 220497-88-1)

The compound 1,2-Cyclopentanediol,3-amino-5-(hydroxymethyl)-, hydrochloride (1:1), (1S,2R,3S,5S)- (CAS No. 220497-88-1) is a specialized chiral molecule with significant potential in pharmaceutical and biochemical research. Its unique stereochemistry and functional groups make it a valuable intermediate in the synthesis of complex organic molecules. Researchers and industry professionals are increasingly interested in this compound due to its applications in drug development and asymmetric synthesis.

One of the key features of 1,2-Cyclopentanediol,3-amino-5-(hydroxymethyl)-, hydrochloride (1:1), (1S,2R,3S,5S)- is its stereospecificity, which is crucial for creating enantiomerically pure compounds. This property aligns with the growing demand for chiral drugs, as they often exhibit higher efficacy and fewer side effects compared to racemic mixtures. The compound's hydroxymethyl and amino groups further enhance its reactivity, making it a versatile building block in organic synthesis.

In recent years, the pharmaceutical industry has seen a surge in the development of targeted therapies and personalized medicine. 1,2-Cyclopentanediol,3-amino-5-(hydroxymethyl)-, hydrochloride (1:1), (1S,2R,3S,5S)- plays a pivotal role in this trend, as it can be used to synthesize active pharmaceutical ingredients (APIs) with precise stereochemical configurations. Its application extends to antiviral and anticancer drug research, where molecular specificity is paramount.

The compound's hydrochloride salt form improves its solubility and stability, which are critical factors in formulation development. This aspect is particularly relevant to researchers exploring novel drug delivery systems, such as nanoparticles and liposomes. The ability to fine-tune the physicochemical properties of APIs using intermediates like 1,2-Cyclopentanediol,3-amino-5-(hydroxymethyl)-, hydrochloride (1:1), (1S,2R,3S,5S)- is a hot topic in modern pharmaceutics.

From a synthetic chemistry perspective, the compound's cyclopentanediol backbone offers unique conformational constraints that can influence the biological activity of derived molecules. This structural feature is being exploited in the design of enzyme inhibitors and receptor modulators, addressing current challenges in drug discovery. The integration of computational chemistry and AI-driven molecular modeling has further amplified interest in such structurally diverse intermediates.

Quality control and analytical characterization of 1,2-Cyclopentanediol,3-amino-5-(hydroxymethyl)-, hydrochloride (1:1), (1S,2R,3S,5S)- are essential considerations for researchers. Advanced techniques like HPLC, LC-MS, and NMR spectroscopy are typically employed to verify its purity and stereochemical integrity. These analytical protocols align with the pharmaceutical industry's emphasis on rigorous quality standards and regulatory compliance.

The global market for chiral intermediates is expanding rapidly, driven by the increasing demand for enantiopure drugs. 1,2-Cyclopentanediol,3-amino-5-(hydroxymethyl)-, hydrochloride (1:1), (1S,2R,3S,5S)- is well-positioned to meet this demand, with potential applications spanning multiple therapeutic areas. Its commercial availability and customizable synthesis routes make it attractive for both academic and industrial research programs.

Environmental considerations in chemical synthesis have become a major focus in recent years. The production processes for 1,2-Cyclopentanediol,3-amino-5-(hydroxymethyl)-, hydrochloride (1:1), (1S,2R,3S,5S)- are being optimized to reduce waste and energy consumption, aligning with green chemistry principles. This sustainability aspect is increasingly important to researchers and manufacturers alike.

In conclusion, 1,2-Cyclopentanediol,3-amino-5-(hydroxymethyl)-, hydrochloride (1:1), (1S,2R,3S,5S)- (CAS No. 220497-88-1) represents a valuable tool in modern chemical research and drug development. Its unique structural features, combined with growing applications in targeted therapies, make it a compound of significant interest to the scientific community. As research continues to uncover new applications for this molecule, its importance in pharmaceutical chemistry is likely to increase further.

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