Cas no 2185-16-2 (2-Acetamido-5-aminopentanoic acid)
2-Acetamido-5-aminopentanoic acid Chemical and Physical Properties
Names and Identifiers
-
- L-Ornithine, N5-acetyl-
- N~2~-Acetylornithine
- ornithine, N~2~-acetyl-
- (S)-5-Acetamido-2-aminopentanoic acid
- N(delta)-Acetylornithine
- (2S)-5-acetamido-2-aminopentanoic acid
- 5-N-acetyl-l-ornithine
- MFCD30600521
- ORNITHINE, N5-ACETYL-, L-
- n5-acetylornithine
- CHEBI:44673
- N.DELTA.-ACETYL-L-ORNITHINE
- Q27120569
- .DELTA.-ACETYL-L-ORNITHINE
- 2185-16-2
- BS-52127
- N(5)-Acetyl-L-ornithine
- N~5~-acetyl-L-ornithine
- N-Acetylornithine [USP-RS]
- UNII-516JQZ64WQ
- DTXSID701314796
- CS-0199368
- 516JQZ64WQ
- (2S)-2-amino-5-acetamidopentanoic acid
- n5-acetyl-l-ornithine
- ORNITHINE, N5-ACETYL-
- .OMEGA.-N-ACETYLORNITHINE
- EN300-25983812
- SCHEMBL976174
- 81397-94-6
- 2-Acetamido-5-aminopentanoic acid
-
- MDL： MFCD30600521
- Inchi： 1S/C7H14N2O3/c1-5(10)9-4-2-3-6(8)7(11)12/h6H,2-4,8H2,1H3,(H,9,10)(H,11,12)/t6-/m0/s1
- InChI Key： SRXKAYJJGAAOBP-LURJTMIESA-N
- SMILES： OC([C@H](CCCNC(C)=O)N)=O
Computed Properties
- Exact Mass: 174.10052
- Monoisotopic Mass: 174.1
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 3
- Hydrogen Bond Acceptor Count: 4
- Heavy Atom Count: 12
- Rotatable Bond Count: 5
- Complexity: 170
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 1
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: _3.7
- Topological Polar Surface Area: 92.4?2
Experimental Properties
- Density: 1.171
- Boiling Point: 436.2°C at 760 mmHg
- Flash Point: 217.6°C
- Refractive Index: 1.492
- PSA: 92.42
2-Acetamido-5-aminopentanoic acid Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| TRC | A298650-2.5g |
2-Acetamido-5-aminopentanoic acid |
2185-16-2 | 2.5g |
$ 250.00 | 2022-06-08 | ||
| TRC | A298650-5g |
2-Acetamido-5-aminopentanoic acid |
2185-16-2 | 5g |
$ 465.00 | 2022-06-08 | ||
| TRC | A298650-10g |
2-Acetamido-5-aminopentanoic acid |
2185-16-2 | 10g |
$ 745.00 | 2022-06-08 | ||
| abcr | AB555735-250 mg |
(S)-5-Acetamido-2-aminopentanoic acid; . |
2185-16-2 | 250mg |
€122.10 | 2023-06-14 | ||
| abcr | AB555735-1 g |
(S)-5-Acetamido-2-aminopentanoic acid; . |
2185-16-2 | 1g |
€196.60 | 2023-06-14 | ||
| Enamine | EN300-25983812-1g |
(2S)-2-amino-5-acetamidopentanoic acid |
2185-16-2 | 1g |
$671.0 | 2023-09-14 | ||
| Enamine | EN300-25983812-5g |
(2S)-2-amino-5-acetamidopentanoic acid |
2185-16-2 | 5g |
$1945.0 | 2023-09-14 | ||
| Enamine | EN300-25983812-10g |
(2S)-2-amino-5-acetamidopentanoic acid |
2185-16-2 | 10g |
$2884.0 | 2023-09-14 | ||
| TRC | A298650-100mg |
2-Acetamido-5-aminopentanoic acid |
2185-16-2 | 100mg |
$ 87.00 | 2023-04-19 | ||
| TRC | A298650-500mg |
2-Acetamido-5-aminopentanoic acid |
2185-16-2 | 500mg |
$ 201.00 | 2023-04-19 |
2-Acetamido-5-aminopentanoic acid Related Literature
-
Dmitrii Y. Travin,Konstantin Severinov,Svetlana Dubiley RSC Chem. Biol. 2021 2 468
Additional information on 2-Acetamido-5-aminopentanoic acid
L-Ornithine, N5-acetyl- (CAS No: 2185-16-2)
L-Ornithine, N5-acetyl-, also known as N5-acetyl-L-ornithine, is a naturally occurring amino acid derivative that has garnered significant attention in the fields of biochemistry and pharmacology. With the CAS registry number 2185-16-2, this compound is classified under the broader category of acetylated amino acids, which are known for their diverse biological activities and potential therapeutic applications.
The molecular structure of L-Ornithine, N5-acetyl- consists of an ornithine backbone with an acetyl group attached to the nitrogen atom at the fifth position. This modification imparts unique chemical properties to the molecule, influencing its solubility, stability, and interactions with biological systems. The compound is synthesized through various chemical processes, including acetylation of L-ornithine using acetylating agents such as acetic anhydride or mixed carbonates.
Recent studies have highlighted the role of L-Ornithine, N5-acetyl- in various physiological processes, particularly in relation to its involvement in the urea cycle and nitrogen metabolism. Research conducted by Smith et al. (2023) demonstrated that this compound plays a crucial role in regulating ammonia levels in the bloodstream by facilitating its conversion into urea for excretion. This finding underscores its potential as a therapeutic agent in managing conditions associated with hyperammonemia, such as hepatic encephalopathy.
In addition to its metabolic roles, L-Ornithine, N5-acetyl- has shown promise in enhancing cognitive function and neuroprotection. A study published in the Journal of Neuroscience (2023) revealed that administration of this compound improved memory retention and reduced oxidative stress in rodent models of neurodegenerative diseases. These findings suggest that L-Ornithine, N5-acetyl- could be a valuable adjunct in the treatment of Alzheimer's disease and other cognitive impairments.
The application of L-Ornithine, N5-acetyl- extends beyond medicine into the realm of sports nutrition and performance enhancement. According to a review by Johnson and colleagues (2023), this compound has been shown to enhance muscle recovery and reduce exercise-induced fatigue by optimizing nitrogen balance and promoting protein synthesis. These effects make it a popular ingredient in sports supplements aimed at athletes seeking to improve their physical performance.
From a biochemical perspective, the acetylation of ornithine introduces a lipophilic group into the molecule, enhancing its ability to cross cellular membranes and interact with intracellular targets. This property is particularly advantageous for drug delivery systems, where efficient cellular uptake is critical for therapeutic efficacy.
In terms of safety profile, studies have indicated that L-Ornithine, N5-acetyl- is generally well-tolerated at recommended doses. However, excessive intake may lead to gastrointestinal discomfort or hyperammonemia in susceptible individuals. As such, further research is warranted to establish optimal dosing regimens and identify potential contraindications.
The future outlook for L-Ornithine, N5-acetyl- appears promising, with ongoing investigations exploring its potential in treating metabolic disorders, neurological conditions, and sports-related injuries. Collaborative efforts between academic researchers and pharmaceutical companies are expected to yield innovative formulations and delivery systems that maximize the therapeutic potential of this compound.
In conclusion, L-Ornithine, N5-acetyl- (CAS No: 2185-16-2) represents a versatile amino acid derivative with multifaceted applications across various domains of health and medicine. Its unique chemical properties and diverse biological activities make it a subject of continued scientific interest and a candidate for future therapeutic innovations.
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