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• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Benzodioxanes Benzo-1,4-dioxanes

Comprehensive Overview of 5-(Bromomethyl)-2,3-dihydro-1,4-benzodioxine (CAS No. 214894-89-0)

5-(Bromomethyl)-2,3-dihydro-1,4-benzodioxine (CAS No. 214894-89-0) is a specialized organic compound widely recognized for its versatile applications in pharmaceutical intermediates and material science. This brominated derivative of benzodioxine has garnered significant attention due to its unique molecular structure, which features a reactive bromomethyl group attached to a 2,3-dihydro-1,4-benzodioxine core. Researchers and industries value this compound for its role in synthesizing complex molecules, particularly in drug discovery and agrochemical development.

The compound’s CAS number 214894-89-0 serves as a critical identifier in chemical databases, ensuring precise tracking in regulatory and research contexts. Its systematic name, 5-(Bromomethyl)-2,3-dihydro-1,4-benzodioxine, reflects its IUPAC nomenclature, while alternative names like 5-Bromomethylbenzodioxane may also appear in literature. The presence of the bromomethyl moiety makes it a valuable building block for nucleophilic substitution reactions, enabling the introduction of diverse functional groups in synthetic pathways.

In recent years, the demand for 5-(Bromomethyl)-2,3-dihydro-1,4-benzodioxine has surged due to its relevance in green chemistry and sustainable synthesis. As industries prioritize eco-friendly processes, this compound’s efficiency in catalytic transformations and low-waste reactions aligns with global trends. For instance, its use in cross-coupling reactions—a hot topic in organic chemistry—highlights its potential to reduce reliance on heavy metals or hazardous reagents. Researchers frequently search for terms like "benzodioxine derivatives in drug design" or "bromomethyl applications in catalysis," underscoring its interdisciplinary appeal.

From a structural perspective, the 2,3-dihydro-1,4-benzodioxine scaffold is a privileged motif in medicinal chemistry, often associated with bioactive molecules targeting neurological and cardiovascular systems. The bromomethyl group’s versatility allows for further modifications, such as click chemistry or polymer functionalization, making it a focal point for material scientists. Online queries like "CAS 214894-89-0 supplier" or "benzodioxine bromomethyl synthesis" reflect its commercial and academic demand.

Quality control and analytical methods for 5-(Bromomethyl)-2,3-dihydro-1,4-benzodioxine are rigorously documented, with HPLC and NMR being standard techniques for purity verification. Its stability under controlled conditions ensures reliable performance in lab-scale and industrial applications. Notably, discussions on "scalable synthesis of bromomethylbenzodioxine" or "safe handling of benzodioxine derivatives" dominate forums, emphasizing both its utility and operational considerations.

In summary, 5-(Bromomethyl)-2,3-dihydro-1,4-benzodioxine (CAS No. 214894-89-0) stands at the intersection of innovation and practicality. Its chemical properties, coupled with growing interest in sustainable chemistry and high-value intermediates, position it as a compound of enduring relevance. Whether in peer-reviewed research or industrial workflows, this molecule continues to inspire advancements across multiple scientific domains.

• 22892-33-7(Benzene, 1-(bromomethyl)-2,4,5-tris(phenylmethoxy)-)
• 891197-84-5(Benzene,1,4-bis(bromomethyl)-2,5-bis[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]-)
• 86489-89-6(3-(bromomethyl)-1,2,4,5-tetramethoxybenzene)
• 58402-40-7(Benzene, 1-(bromomethyl)-3-methoxy-2-(phenylmethoxy)-)
• 89048-14-6(Benzene, 1-(bromomethyl)-2,3,4,5-tetramethoxy-6-methyl-)
• 79440-34-9(6-(Bromomethyl)-2,3-dihydrobenzob1,4dioxine)
• 80054-01-9(1-(bromomethyl)-2,3,4-trimethoxybenzene)
• 499770-96-6(6-(Bromomethyl)-3,4-dihydro-2H-1,5-benzodioxepine)
• 2417-70-1(1-(bromomethyl)-2-ethoxybenzene)
• 54636-77-0(1-(Bromomethyl)-2,3-dimethoxybenzene)