Cas no 2138178-85-3 (5-(2-methoxyethoxy)-4-methylpyrimidin-2-amine)
5-(2-Methoxyethoxy)-4-methylpyrimidin-2-amine is a pyrimidine derivative with potential applications in pharmaceutical and agrochemical research. Its structure features a methoxyethoxy substituent at the 5-position and a methyl group at the 4-position, contributing to its unique reactivity and solubility profile. This compound may serve as a versatile intermediate in the synthesis of biologically active molecules, particularly in the development of kinase inhibitors or nucleoside analogs. The presence of the amine group at the 2-position enhances its ability to participate in further functionalization, making it valuable for structure-activity relationship studies. Its balanced lipophilicity, influenced by the methoxyethoxy side chain, may improve bioavailability in drug discovery applications.
2138178-85-3 structure
Product Name:5-(2-methoxyethoxy)-4-methylpyrimidin-2-amine
CAS No:2138178-85-3
MF:C8H13N3O2
MW:183.207721471786
CID:6008032
PubChem ID:165484906
Update Time:2025-06-07
5-(2-methoxyethoxy)-4-methylpyrimidin-2-amine Chemical and Physical Properties
Names and Identifiers
-
- 5-(2-methoxyethoxy)-4-methylpyrimidin-2-amine
- 2138178-85-3
- EN300-1122184
-
- Inchi: 1S/C8H13N3O2/c1-6-7(13-4-3-12-2)5-10-8(9)11-6/h5H,3-4H2,1-2H3,(H2,9,10,11)
- InChI Key: DFOWMBXEAKAFRI-UHFFFAOYSA-N
- SMILES: O(C1=CN=C(N)N=C1C)CCOC
Computed Properties
- Exact Mass: 183.100776666g/mol
- Monoisotopic Mass: 183.100776666g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 5
- Heavy Atom Count: 13
- Rotatable Bond Count: 4
- Complexity: 145
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 0.1
- Topological Polar Surface Area: 70.3?2
5-(2-methoxyethoxy)-4-methylpyrimidin-2-amine Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Enamine | EN300-1122184-0.05g |
5-(2-methoxyethoxy)-4-methylpyrimidin-2-amine |
2138178-85-3 | 95% | 0.05g |
$612.0 | 2023-10-27 | |
| Enamine | EN300-1122184-0.1g |
5-(2-methoxyethoxy)-4-methylpyrimidin-2-amine |
2138178-85-3 | 95% | 0.1g |
$640.0 | 2023-10-27 | |
| Enamine | EN300-1122184-0.25g |
5-(2-methoxyethoxy)-4-methylpyrimidin-2-amine |
2138178-85-3 | 95% | 0.25g |
$670.0 | 2023-10-27 | |
| Enamine | EN300-1122184-0.5g |
5-(2-methoxyethoxy)-4-methylpyrimidin-2-amine |
2138178-85-3 | 95% | 0.5g |
$699.0 | 2023-10-27 | |
| Enamine | EN300-1122184-1.0g |
5-(2-methoxyethoxy)-4-methylpyrimidin-2-amine |
2138178-85-3 | 1g |
$728.0 | 2023-06-09 | ||
| Enamine | EN300-1122184-2.5g |
5-(2-methoxyethoxy)-4-methylpyrimidin-2-amine |
2138178-85-3 | 95% | 2.5g |
$1428.0 | 2023-10-27 | |
| Enamine | EN300-1122184-5.0g |
5-(2-methoxyethoxy)-4-methylpyrimidin-2-amine |
2138178-85-3 | 5g |
$2110.0 | 2023-06-09 | ||
| Enamine | EN300-1122184-10.0g |
5-(2-methoxyethoxy)-4-methylpyrimidin-2-amine |
2138178-85-3 | 10g |
$3131.0 | 2023-06-09 | ||
| Enamine | EN300-1122184-1g |
5-(2-methoxyethoxy)-4-methylpyrimidin-2-amine |
2138178-85-3 | 95% | 1g |
$728.0 | 2023-10-27 | |
| Enamine | EN300-1122184-5g |
5-(2-methoxyethoxy)-4-methylpyrimidin-2-amine |
2138178-85-3 | 95% | 5g |
$2110.0 | 2023-10-27 |
5-(2-methoxyethoxy)-4-methylpyrimidin-2-amine Related Literature
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Eunice Y.-L. Hui,Bhimsen Rout,Yaw Sing Tan,Kok-Ping Chan,Charles W. Johannes Org. Biomol. Chem., 2018,16, 389-392
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Xin Fu,Qing-rong Liang,Rong-guang Luo,Yan-shu Li,Xiao-ping Xiao,Lu-lu Yu,Wen-zhe Shan,Guang-qin Fan J. Mater. Chem. B, 2019,7, 3088-3099
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Philipp Traber,Stephan Kupfer,Stefanie Gr?fe,Isabelle Baussanne,Martine Demeunynck,Jean-Marie Mouesca,Serge Gambarelli,Vincent Artero,Murielle Chavarot-Kerlidou Chem. Sci., 2018,9, 4152-4159
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Xixi Li,Nanwei Zhu,Ruohan Li,Qinpu Zhang Anal. Methods, 2020,12, 3376-3381
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