Cas no 2135-17-3 (Flumethasone)

Flumethasone is a synthetic corticosteroid known for its potent anti-inflammatory activity. Its key advantages include rapid onset of action and high efficacy in treating skin conditions such as eczema and psoriasis, with minimal systemic side effects when applied topically. Its lipophilic nature enhances penetration into the skin, further contributing to its effectiveness.
Flumethasone structure
Flumethasone structure
Product Name:Flumethasone
CAS No:2135-17-3
MF:C22H28F2O5
MW:410.45153427124
MDL:MFCD00056464
CID:42504
PubChem ID:16490
Update Time:2025-11-05

Flumethasone Chemical and Physical Properties

Names and Identifiers

    • flumethasone
    • 6-alpha,9-alpha-difluoro-11-beta,17-alpha,21-trihydroxy-16-alpha-methylpregna-1,4-diene-3,20-dione
    • (6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
    • Flumetasone
    • 6α,9α-Difluoro-16α-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione
    • 6α,9α-Difluoro-16α-methylprednisolone
    • 6α-Fluorodexamethasone
    • Anaprime
    • Aniprime
    • Cortexilar
    • Flucorticin
    • Flumethason
    • Fluvet
    • Methagon
    • 6a,9a-Difluoro-16a-methyl-11b,17a,21-trihydroxy-1,4-pregnadiene-3,20-dione
    • 6a,9a-Difluoro-16a-methylprednisolone
    • 6alpha-Fluorodexamethasone
    • Flumetasonum
    • Flumetasona
    • Flumethasonum
    • RS 2177
    • Flucort (Veterinary)
    • Flumetasonum [INN-Latin]
    • Flumetasona [INN-Spanish]
    • 6-alpha-Fluorodexamethasone
    • LR3CD8SX89
    • MLS000028618
    • Flumetason
    • AC-2069
    • D07AB03
    • NCGC00021761-03
    • Prestwick0_000734
    • AKOS005256462
    • U-10974
    • Q-101387
    • BRD-K61496577-001-03-8
    • AMY38487
    • EN300-19734521
    • Flumetasone [INN]
    • U-10,974
    • Opera_ID_1501
    • EC 218-370-9
    • 6.alpha., 9.alpha.-Difluoro-16.alpha.-methylprednisolone
    • DTXCID0025365
    • NCGC00016604-01
    • Pregna-1,4-diene-3,20-dione, 6alpha,9-difluoro-11beta,17,21-trihydroxy-16alpha-methyl-(VAN)
    • C22H28F2O5
    • NCGC00021761-05
    • SMP1_000127
    • Flumetasonum (INN-Latin)
    • UNII-LR3CD8SX89
    • AS-12534
    • SR-01000003144
    • FLUMETASONE [WHO-DD]
    • RS-2177
    • BSPBio_000688
    • Flucort Solution
    • Prestwick1_000734
    • Prestwick_229
    • 6.alpha.-Fluorodexamethasone
    • MFCD00056464
    • NSC54702
    • 6.alpha., 9-Difluoro-11.beta.,17,21-trihydroxy-16.alpha.-methylpregna-1, 4-diene-3,20-dione
    • NCGC00021761-06
    • (6?,11?,16?)-6,9-Difluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione
    • CHEBI:34764
    • T72075
    • s4088
    • Pregna-1,4-diene-3,20-dione, 6,9-difluoro-11,17, 21-trihydroxy-16-methyl-, (6.alpha.,11.beta.,16.alpha.)-
    • DTXSID2045365
    • HMS1570C10
    • EINECS 218-370-9
    • D04208
    • Flumetasone (INN)
    • Flumethasone (USAN)
    • Tox21_110518_1
    • (6alpha,11beta,16alpha)-6,9-difluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione
    • CS-4573
    • Flumethasone [USAN]
    • Tox21_110518
    • Bimasone
    • (6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one
    • SR-01000003144-3
    • F0945
    • HMS3714C10
    • A855571
    • MLS001077306
    • SCHEMBL4046
    • SMR000058690
    • CCG-220734
    • Flumetasona (INN-Spanish)
    • CAS-2135-17-3
    • Pregna-1,4-diene-3,20-dione,6,9-difluoro-11,17,21-trihydroxy-16-methyl-, (6a,11b,16a)-
    • D07XB01
    • 6alpha,9alpha-Difluoro-16alpha-methyl-11beta,17alpha,21-trihydroxy-1,4-pregnadiene-3,20-dione
    • Anaprime Suspension
    • Prestwick3_000734
    • NS00001953
    • BRD-K61496577-001-20-2
    • Flucort Tablets
    • Pregna-1,4-diene-3,20-dione, 6,9-difluoro-11,17,21-trihydroxy-16-methyl-, (6.alpha.,11.beta.,16.alpha.)-
    • 6alpha,9alpha-Difluoro-16alpha-methylprednisolone
    • HMS2097C10
    • 6alpha-Fluoro-dexamethasone
    • BRN 5645455
    • (1R,2R,3aS,3bS,5S,9aS,9bR,10S,11aS)-5,9b-difluoro-1,10-dihydroxy-1-(2-hydroxyacetyl)-2,9a,11a-trimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-one
    • 6,9-Difluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione
    • DB00663
    • Q4383636
    • HY-B1051
    • CHEMBL1201392
    • 6alpha,9-Difluoro-11beta,17,21-trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione (Flumetasone)
    • 2135-17-3
    • NSC 54702
    • WXURHACBFYSXBI-GQKYHHCASA-N
    • flumethasoni pivalas
    • Prestwick2_000734
    • BPBio1_000758
    • FLUMETHASONE [GREEN BOOK]
    • Pregna-1,4-diene-3,20-dione, 6.alpha.,9-difluoro-11.beta.,17,21-trihydroxy-16.alpha.-methyl-
    • FLUMETHASONE [MI]
    • SPBio_002627
    • NSC-54702
    • 6alpha,9-Difluoro-11beta,17,21-trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione
    • (6S,9R,10S,11S,13S,16R,17R)-6,9-Difluoro-11,17-dihydroxy-17-(2-hydroxy-acetyl)-10,13,16-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-cyclopenta[a]phenanthren-3-one
    • Fluorodexamethasone
    • HMS2234B11
    • AKOS015895435
    • GLXC-20122
    • (6a,11b,16a)-6,9-Difluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione
    • HY-B1051R
    • 218-370-9
    • Flumethasone (Standard)
    • FF23328
    • Flumethasone
    • MDL: MFCD00056464
    • Inchi: 1S/C22H28F2O5/c1-11-6-13-14-8-16(23)15-7-12(26)4-5-19(15,2)21(14,24)17(27)9-20(13,3)22(11,29)18(28)10-25/h4-5,7,11,13-14,16-17,25,27,29H,6,8-10H2,1-3H3/t11-,13+,14+,16+,17+,19+,20+,21+,22+/m1/s1
    • InChI Key: WXURHACBFYSXBI-GQKYHHCASA-N
    • SMILES: F[C@@]12[C@]3(C=CC(C=C3[C@H](C[C@H]1[C@@H]1C[C@@H](C)[C@](C(CO)=O)([C@@]1(C)C[C@@H]2O)O)F)=O)C

Computed Properties

  • Exact Mass: 410.19000
  • Monoisotopic Mass: 410.19048
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 3
  • Hydrogen Bond Acceptor Count: 7
  • Heavy Atom Count: 29
  • Rotatable Bond Count: 2
  • Complexity: 839
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 9
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Surface Charge: 0
  • Tautomer Count: 3
  • XLogP3: 1.9
  • Topological Polar Surface Area: 94.8

Experimental Properties

  • Color/Form: Powder
  • Density: 1.1621 (estimate)
  • Melting Point: 237-240°C
  • Boiling Point: 569.8°C at 760 mmHg
  • Flash Point: 298.4 °C
  • Refractive Index: 1.579
  • Solubility: acetic acid: soluble10mg/mL
  • PSA: 94.83000
  • LogP: 1.84370
  • Merck: 14,4138

Flumethasone Security Information

  • Signal Word:Warning
  • Hazard Statement: H302
  • Warning Statement: P280-P305+P351+P338
  • WGK Germany:3
  • Hazard Category Code: R40
  • Safety Instruction: S22-S36
  • RTECS:TU3832000
  • Hazardous Material Identification: Xn
  • Safety Term:S22;S36
  • Risk Phrases:R40
  • Storage Condition:Powder -20°C 3 years ? 4°C 2 years In solvent -80°C 6 months ? -20°C 1 month

Flumethasone Customs Data

  • HS CODE:2937229000
  • Customs Data:

    China Customs Code:

    2937229000

Flumethasone Pricemore >>

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Flumethasone Production Method

Flumethasone Suppliers

Tiancheng Chemical (Jiangsu) Co., Ltd
Gold Member
Audited Supplier Audited Supplier
(CAS:2135-17-3)氟米松
Order Number:LE27038642;LE10660;LE2796
Stock Status:in Stock
Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Friday, 20 June 2025 13:02
Price ($):discuss personally
Suzhou Senfeida Chemical Co., Ltd
Gold Member
Audited Supplier Audited Supplier
(CAS:2135-17-3)Flumethasone
Order Number:sfd5453
Stock Status:in Stock
Quantity:200kg
Purity:99.9%
Pricing Information Last Updated:Friday, 19 July 2024 14:34
Price ($):discuss personally

Flumethasone Spectrogram

13C NMR
13C NMR
1H NMR 300 MHz DMSO
1H NMR
Recommended suppliers
Tiancheng Chemical (Jiangsu) Co., Ltd
(CAS:2135-17-3)氟米松
LE27038642;LE10660;LE2796
Purity:99%/99%/99%
Quantity:25KG,200KG,1000KG/25KG,200KG,1000KG/25KG,200KG,1000KG
Price ($):Inquiry/Inquiry/Inquiry
Email
Suzhou Senfeida Chemical Co., Ltd
(CAS:2135-17-3)Flumethasone
sfd5453
Purity:99.9%
Quantity:200kg
Price ($):Inquiry
Email