Cas no 194613-74-6 (A'-Neo-24-norgammacera-4(23),22(29)-diene-3,6-diol, (3b,6b,21b)-)
A'-Neo-24-norgammacera-4(23),22(29)-diene-3,6-diol, (3b,6b,21b)- Chemical and Physical Properties
Names and Identifiers
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- A'-Neo-24-norgammacera-4(23),22(29)-diene-3,6-diol, (3b,6b,21b)-
- 21αH-24-Norhopa-4(23),22(29)-die
- 21αH-24-Norhopa-4(23),22(29)-diene-3β,6β-diol
- 21ALPHAH-24-NORHOPA-4(23),22(29)-DIENE-3BETA,6BETA-DIOL
- 24-Nor-hopa-4(23),22(29)-diene-3β,6β-diol
- [ "" ]
- 24-Norhopa-4(23),22(29)-diene-3β,6β-diol
- 21aH-24-Norhopa-4(23),22(29)-diene-3b,6b-diol
- 24-Norhopa-4(23),22(29)-diene-3beta,6beta-diol
- (3beta,6beta,21beta)-A'-Neo-24-norgammacera-4(23),22(29)-diene-3,6-diol
- 194613-74-6
- AKOS032962507
- (3R,3aS,5aR,5bR,7R,7aR,9S,11aR,11bR,13aR,13bS)-5a,5b,11a,13b-tetramethyl-8-methylidene-3-prop-1-en-2-yl-1,2,3,3a,4,5,6,7,7a,9,10,11,11b,12,13,13a-hexadecahydrocyclopenta[a]chrysene-7,9-diol
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- Inchi: 1S/C29H46O2/c1-17(2)19-10-13-26(4)20(19)11-15-28(6)23(26)8-9-24-27(5)14-12-21(30)18(3)25(27)22(31)16-29(24,28)7/h19-25,30-31H,1,3,8-16H2,2,4-7H3
- InChI Key: SSBVUUVGCIMTCL-UHFFFAOYSA-N
- SMILES: CC(C1C2CCC3(C4(C(C5(C(C(C4)O)C(=C)C(O)CC5)C)CCC3C2(C)CC1)C)C)=C
Computed Properties
- Exact Mass: 426.349780706g/mol
- Monoisotopic Mass: 426.349780706g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 2
- Hydrogen Bond Acceptor Count: 2
- Heavy Atom Count: 31
- Rotatable Bond Count: 1
- Complexity: 801
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 11
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 7.4
- Topological Polar Surface Area: 40.5?2
Experimental Properties
- Color/Form: Powder
- Density: 1.1±0.0 g/cm3
- Boiling Point: 519.5±0.0 °C at 760 mmHg
- Flash Point: 213.8±0.0 °C
- Vapor Pressure: 0.0±0.0 mmHg at 25°C
A'-Neo-24-norgammacera-4(23),22(29)-diene-3,6-diol, (3b,6b,21b)- Security Information
- Hazard Statement: H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body
- Warning Statement: P264+P280+P305+P351+P338+P337+P313
- Safety Instruction: H303+H313+H333
- Storage Condition:Store at 4 ℃, better at -4 ℃
A'-Neo-24-norgammacera-4(23),22(29)-diene-3,6-diol, (3b,6b,21b)- Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd. | H39650-5mg |
(3R,3aS,5aR,5bR,7R,7aR,9S,11aR,11bR,13aR,13bS)-5a,5b,11a,13b-tetramethyl-8-methylene-3-(prop-1-en-2-yl)icosahydro-1H-cyclopenta[a]chrysene-7,9-diol |
194613-74-6 | ,HPLC≥98% | 5mg |
¥4418.0 | 2023-09-07 | |
| TargetMol Chemicals | TN2823-5 mg |
24-Norhopa-4(23),22(29)-diene-3?2,6?2-diol |
194613-74-6 | 98% | 5mg |
¥ 4,280 | 2023-07-11 | |
| TargetMol Chemicals | TN2823-1 mL * 10 mM (in DMSO) |
24-Norhopa-4(23),22(29)-diene-3?2,6?2-diol |
194613-74-6 | 98% | 1 mL * 10 mM (in DMSO) |
¥ 4,380 | 2023-07-11 | |
| TargetMol Chemicals | TN2823-5mg |
24-Norhopa-4(23),22(29)-diene-3?2,6?2-diol |
194613-74-6 | 5mg |
¥ 4280 | 2024-07-20 | ||
| TargetMol Chemicals | TN2823-1 ml * 10 mm |
24-Norhopa-4(23),22(29)-diene-3?2,6?2-diol |
194613-74-6 | 1 ml * 10 mm |
¥ 4380 | 2024-07-20 | ||
| TargetMol Chemicals | TN2823-5mg |
24-Norhopa-4(23),22(29)-diene-3?2,6?2-diol |
194613-74-6 | 5mg |
¥ 4280 | 2024-07-24 | ||
| TargetMol Chemicals | TN2823-1 ml * 10 mm |
24-Norhopa-4(23),22(29)-diene-3?2,6?2-diol |
194613-74-6 | 1 ml * 10 mm |
¥ 4380 | 2024-07-24 |
A'-Neo-24-norgammacera-4(23),22(29)-diene-3,6-diol, (3b,6b,21b)- Related Literature
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C. Achilli,G. F. Guidetti,A. Ciana,D. Capsoni,G. Minetti Biomater. Sci., 2016,4, 1417-1421
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2. Excimer emission and magnetoluminescence of radical-based zinc(ii) complexes doped in host crystals?Shojiro Kimura,Tetsuro Kusamoto Chem. Commun., 2020,56, 11195-11198
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Dongjia Han,Bing Xue,Juan Du,Tomohiro Miyatake,Hitoshi Tamiaki,Xin Xing,Wei Yuan,Yanyan Li Phys. Chem. Chem. Phys., 2016,18, 24252-24260
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Ji-Ping Wei Nanoscale, 2015,7, 11815-11832
Additional information on A'-Neo-24-norgammacera-4(23),22(29)-diene-3,6-diol, (3b,6b,21b)-
Introduction to A'-Neo-24-norgammacera-4(23),22(29)-diene-3,6-diol, (3b,6b,21b) and Its Significance in Modern Chemical Biology
The compound with the CAS number 194613-74-6, identified as A'-Neo-24-norgammacera-4(23),22(29)-diene-3,6-diol, (3b,6b,21b), represents a fascinating molecule in the realm of chemical biology. This triterpenoid derivative has garnered attention due to its unique structural configuration and potential biological activities. The stereochemistry defined by the (3b,6b,21b) notation underscores its distinct three-dimensional arrangement, which is critical for its interaction with biological targets.
Recent advancements in the field of natural product chemistry have highlighted the importance of triterpenoids in drug discovery. Triterpenoids, a class of terpenes with multiple isoprene units, are known for their diverse pharmacological profiles. Among these, A'-Neo-24-norgammacera-4(23),22(29)-diene-3,6-diol, (3b,6b,21b) stands out due to its complex stereochemistry and potential bioactivity. The presence of double bonds at positions 4(23) and 22(29) contributes to its structural rigidity and may influence its biological interactions.
Structurally speaking, this compound belongs to the neo-gammacera family of triterpenoids. The term "neo" indicates a modification from the parent compound by the removal of an isoprene unit. This structural simplification often enhances bioavailability and binding affinity to biological targets. The diol functional groups at positions 3 and 6 further contribute to its reactivity and potential applications in synthetic chemistry.
In terms of biological activity, A'-Neo-24-norgammacera-4(23),22(29)-diene-3,6-diol, (3b,6b,21b) has been studied for its potential roles in modulating various biological pathways. Preliminary studies suggest that this compound may exhibit anti-inflammatory properties by interacting with specific receptors or enzymes involved in inflammation cascades. Additionally, its structural similarity to known steroid hormones suggests possible applications in endocrine research.
The stereochemistry of this compound is particularly noteworthy. The configuration at the (3b,6b,21b) positions determines how it interacts with biological molecules. Stereoisomers of triterpenoids can exhibit vastly different biological activities due to differences in their spatial arrangement. This complexity makes compounds like A'-Neo-24-norgammacera-4(23),22(29)-diene-3,6-diol, (3b,6b,21b) valuable tools for studying enzyme mechanisms and receptor binding.
Recent research has also explored the synthetic pathways leading to the formation of this compound. The development of efficient synthetic routes is crucial for both academic research and industrial applications. Advances in organic synthesis have enabled the construction of complex triterpenoids like this one with high precision and yield. These synthetic methods are not only important for producing individual compounds but also for generating libraries of derivatives for high-throughput screening.
The pharmacological potential of A'-Neo-24-norgammacera-4(23),22(29)-diene-3,6-diol, (3b,6b,21b) has prompted investigations into its effects on various disease models. For instance, studies in cell culture systems have shown that this compound can inhibit the proliferation of certain cancer cell lines by disrupting key signaling pathways. Such findings highlight its potential as a lead compound for further drug development.
Moreover,the compound's interaction with enzymes has been a focus of interest. Enzymes are critical targets for many therapeutic agents due to their central role in metabolic pathways. By understanding how A'-Neo-24-norgammacera-4(23),22(29)-diene-3,6-diol, (3b,6b,21b) interacts with specific enzymes, researchers can gain insights into its mechanism of action and identify ways to enhance its efficacy or selectivity.
The stereochemical purity of this compound is another important consideration. Impurities or racemic mixtures can significantly alter biological activity and necessitate careful purification techniques. Advances in chromatography and spectroscopy have made it possible to obtain highly pure samples of complex molecules like this one.
In conclusion,A'-Neo-24-norgammacera-4(23),22(29)-diene-3,6-diol, (3b, 6b, 21 b) represents a promising molecule in chemical biology with significant potential for further research and development。 Its unique structure, stereochemistry, and bioactivity make it a valuable tool for studying various biological processes。 As research continues,this compound may contribute to new therapeutic strategies and deepen our understanding of triterpenoid biochemistry。
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