Cas no 19319-32-5 ((2Z)-3-(4-Methoxyphenyl)-2-phenylacrylic Acid)

(2Z)-3-(4-Methoxyphenyl)-2-phenylacrylic acid is a cinnamic acid derivative characterized by its (Z)-stereochemistry and substituted aromatic rings. This compound is of interest in synthetic organic chemistry due to its conjugated double bond system and electron-donating methoxy group, which influence its reactivity and photophysical properties. It serves as a versatile intermediate in the synthesis of pharmaceuticals, agrochemicals, and functional materials. The presence of both phenyl and 4-methoxyphenyl groups enhances its potential for further functionalization, making it valuable for cross-coupling reactions and polymer applications. Its crystalline nature facilitates purification, while its structural features contribute to studies in molecular electronics and nonlinear optics.
(2Z)-3-(4-Methoxyphenyl)-2-phenylacrylic Acid structure
19319-32-5 structure
Product Name:(2Z)-3-(4-Methoxyphenyl)-2-phenylacrylic Acid
CAS No:19319-32-5
MF:C16H14O3
MW:254.280564785004
CID:1081208
PubChem ID:816807
Update Time:2025-10-21

(2Z)-3-(4-Methoxyphenyl)-2-phenylacrylic Acid Chemical and Physical Properties

Names and Identifiers

    • (Z)-3-(4-Methoxyphenyl)-2-phenylacrylic acid
    • (2Z)-3-(4-Methoxyphenyl)-2-phenylacrylic acid
    • 3-(4-Methoxyphenyl)-2-phenylacrylic acid
    • (E)-2-phenyl-3-(4-methoxyphenyl)propenoic acid
    • (E)-3-(4-methoxyphenyl)-2-phenyl-2-propenoic acid
    • (E)-3-(4-methoxyphenyl)-2-phenylacrylic acid
    • (E)-3-(4-methoxyphenyl)-2-phenylpropenoic acid
    • benzyl-NNO-azoxymethane
    • CTK2I2934
    • Diazene, methyl(phenylmethyl)-, 1-oxide
    • (Z)-3-(4-methoxyphenyl)-2-phenyl-acrylic acid
    • 3-(4-methoxyphenyl)-2-phenylprop-2-enoic acid
    • 3-(4-methoxyphenyl)-2-phenyl-prop-2-enoic acid
    • (Z)-3-(4-methoxyphenyl)-2-phenylprop-2-enoic acid
    • (Z)-3-(4-methoxyphenyl)-2-phenyl-prop-2-enoic acid
    • Benzeneacetic acid, alpha-[(4-methoxyphenyl)methylene]-
    • (2Z)-3-(4-methoxyphenyl)-2-phenylacrylic acid(SALTDATA: FREE)
    • SR-01000032000
    • AKOS001027578
    • NSC66265
    • (2Z)-3-(4-METHOXYPHENYL)-2-PHENYLACRYLIC ACID 95%
    • MFCD00598899
    • SCHEMBL13950671
    • 6968-77-0
    • NSC-39459
    • (Z)-3-(4-Methoxyphenyl)-2-phenylacrylicacid
    • SR-01000032000-1
    • F16361
    • NSC638183
    • NSC-66265
    • Z56823404
    • 19319-32-5
    • NSC39459
    • AB-131/40897239
    • (2Z)-3-(4-Methoxyphenyl)-2-phenylacrylic Acid
    • MDL: MFCD00598899
    • Inchi: 1S/C16H14O3/c1-19-14-9-7-12(8-10-14)11-15(16(17)18)13-5-3-2-4-6-13/h2-11H,1H3,(H,17,18)/b15-11-
    • InChI Key: NHUQYXSTNXLJIW-PTNGSMBKSA-N
    • SMILES: O(C)C1C=CC(=CC=1)/C=C(\C(=O)O)/C1C=CC=CC=1

Computed Properties

  • Exact Mass: 254.09432
  • Monoisotopic Mass: 254.094294304g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 19
  • Rotatable Bond Count: 4
  • Complexity: 321
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 1
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 3.5
  • Topological Polar Surface Area: 46.5?2

Experimental Properties

  • PSA: 46.53

(2Z)-3-(4-Methoxyphenyl)-2-phenylacrylic Acid Pricemore >>

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Additional information on (2Z)-3-(4-Methoxyphenyl)-2-phenylacrylic Acid

Comprehensive Overview of (2Z)-3-(4-Methoxyphenyl)-2-phenylacrylic Acid (CAS No. 19319-32-5)

(2Z)-3-(4-Methoxyphenyl)-2-phenylacrylic Acid, with the CAS number 19319-32-5, is a specialized organic compound that has garnered significant attention in pharmaceutical and chemical research. This compound, characterized by its unique Z-configuration and aryl-substituted acrylic acid structure, plays a pivotal role in the synthesis of bioactive molecules. Its methoxyphenyl and phenyl moieties contribute to its distinct chemical properties, making it a valuable intermediate in medicinal chemistry.

In recent years, the demand for (2Z)-3-(4-Methoxyphenyl)-2-phenylacrylic Acid has surged due to its potential applications in drug discovery and material science. Researchers are particularly interested in its role as a building block for designing anti-inflammatory and antioxidant agents. The compound's ability to modulate biological pathways has also made it a subject of study in cancer research, aligning with the growing focus on targeted therapies.

The synthesis of CAS 19319-32-5 involves sophisticated organic reactions, such as Wittig olefination or Knoevenagel condensation, to achieve the desired Z-isomer. Its stereochemistry is critical for its biological activity, as even minor changes can alter its efficacy. This specificity has led to its inclusion in high-throughput screening libraries, where it is evaluated for structure-activity relationships (SAR).

From an industrial perspective, (2Z)-3-(4-Methoxyphenyl)-2-phenylacrylic Acid is valued for its scalable production and high purity standards. Manufacturers emphasize green chemistry principles to minimize environmental impact, a topic increasingly relevant to sustainable development goals (SDGs). The compound's low toxicity profile further enhances its appeal for pharmaceutical formulations.

Analytical techniques like HPLC, NMR, and mass spectrometry are essential for characterizing 19319-32-5, ensuring compliance with regulatory guidelines. Its solubility in organic solvents and thermal stability are also well-documented, facilitating its use in diverse laboratory protocols.

As the scientific community explores precision medicine and AI-driven drug design, compounds like (2Z)-3-(4-Methoxyphenyl)-2-phenylacrylic Acid are poised to play a transformative role. Its integration into computational models and virtual screening platforms underscores its relevance in modern biotechnology.

In summary, CAS 19319-32-5 exemplifies the intersection of chemical innovation and therapeutic potential. Its multifaceted applications, from bench research to industrial synthesis, highlight its importance in advancing health sciences and material engineering.

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