Cas no 18942-49-9 (Boc-D-Phe-OH)
Boc-D-Phe-OH, or N-tert-butoxycarbonyl-D-phenylalanine, is a protected derivative of D-phenylalanine widely used in peptide synthesis. Its key advantages include the Boc (tert-butoxycarbonyl) protecting group, which offers stability under basic conditions and selective deprotection under acidic conditions, facilitating controlled peptide chain elongation. The D-configuration of the phenylalanine moiety is valuable for constructing peptides with specific stereochemical requirements, often enhancing metabolic stability or biological activity. This compound exhibits high purity and compatibility with standard coupling reagents, ensuring efficient incorporation into peptide sequences. Its crystalline form allows for easy handling and accurate weighing, making it a reliable building block in solid-phase and solution-phase peptide synthesis.
Boc-D-Phe-OH structure
Product Name:Boc-D-Phe-OH
CAS No:18942-49-9
MF:C14H19NO4
MW:265.30496430397
MDL:MFCD00063149
CID:51182
PubChem ID:637610
Update Time:2025-05-28
Boc-D-Phe-OH Chemical and Physical Properties
Names and Identifiers
-
- N-Boc-D-Phenylalanine
- Boc-D-Phe-OH
- N-(tert-Butoxycarbonyl)-D-phenylalanine
- BOC-D-Phenylalanine
- (2R)-2-[(tert-butoxy)carbonylamino]-3-phenylpropanoic acid
- (R)-N-(tert-butoxycarbonyl)phenylalanine
- BOC-D-PHE
- N-(t-butoxycarbonyl)-D-phenylalanine
- N-(t-butyloxycarbonyl)-D-Phenylalanine
- N-(t-Butyloxycarbonyl)-R-phenylalanine
- N-t-BOC-D-phenylalanine
- N-t-Butoxycarbonyl-D-phenylalanine
- RARECHEM AL BE 0806
- BOC-D-PHENYLALANINE-OH
- Bortezomib Impurity 28
- Boc-D-Phe-OH ,≥99%
- BOC-D-Phenylalanine, 99+%
- ZYJPUMXJBDHSIF-LLVKDONJSA-N
- d-Phenylalanine, N-[(1,1-dimethylethoxy)carbonyl]-
- (2R)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoic acid
- (2R)-2-{[(tert-butoxy)carbonyl]amino}-3-phenylpropanoic acid
- (R)-2-(TERT-BUTOXYCARBONYLAMINO)-3-PHENYLPROPANOIC ACID
- BocDPheOH
- AK
- B2989
- A813323
- N-tert-butyloxycarbonyl-D-phenylalanine
- tert.-butoxycarbonyl-D-phenylalanine
- Q-101753
- AM82156
- CS-W010128
- Z285139170
- Boc-D-Phe-OH, >=99.0% (sum of enantiomers, TLC)
- Boc-D-phenyl-alanine
- AKOS015888245
- Boc-DPhe-OH
- DS-13505
- M03311
- N-tert-butoxycarbonyl-beta-phenyl-D-alanine
- HY-W009412
- (2R)-2-tert-butoxycarbonylamino-3-phenylpropionic acid
- DTXSID50348469
- N-(tert-Butoxycarbonyl)phenylalanine #
- Boc-D-PheOH
- N-Boc-D-Phe
- J-300206
- 18942-49-9
- AKOS015924106
- N-alpha-tert-Butyloxycarbonyl-D-phenylalanine
- 2-(tert-butoxycarbonylamino)-3-phenyl-propanoate;N-Boc-D-phenylalanine
- (TERT-BUTOXYCARBONYL)-D-PHENYLALANINE
- MFCD00063149
- Boc-(D)Phe-OH
- t-butoxycarbonyl-D-phenylalanine
- EN300-35010
- tert-butyloxycarbonyl-d-phenylalanine
- (2R)-2-tert-butoxycarbonylamino-3-phenyl-propionic acid
- SCHEMBL606309
- (R)-tert-butoxycarbonylamino-3-phenyl-propionic acid
- (2R)-2-[[(tert-butoxy)carbonyl]amino]-3-phenylpropanoic acid
- n-tert-butoxycarbonyl-d-phenylalanine
- (2R)-2-[(tert-butoxycarbonyl)amino]-3-phenylpropionic acid
- (R)-2-[(tert-butoxycarbonyl)amino]-3-phenylpropionic acid
- (2R)-2-(tert-butoxycarbonylamino)-3-phenylpropanoic acid
- tert-butoxycarbonyl-D-phenylalanine
- (R)-2-((tert-butoxycarbonyl)amino)-3-phenylpropionic acid
- (2R)-2-[(tert-butoxycarbonyl)amino]-3-phenylpropanoic acid
- CHEBI:231572
- N-[(1,1-DIMETHYLETHOXY)CARBONYL]-D-PHENYLALANINE
- (R)-2-tert-butoxycarbonylamino-3-phenylpropionic acid
-
- MDL： MFCD00063149
- Inchi： 1S/C14H19NO4/c1-14(2,3)19-13(18)15-11(12(16)17)9-10-7-5-4-6-8-10/h4-8,11H,9H2,1-3H3,(H,15,18)(H,16,17)/t11-/m1/s1
- InChI Key： ZYJPUMXJBDHSIF-LLVKDONJSA-N
- SMILES： O(C(N[C@@H](C(=O)O)CC1C=CC=CC=1)=O)C(C)(C)C
- BRN： 4695945
Computed Properties
- Exact Mass: 265.13100
- Monoisotopic Mass: 265.131
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 2
- Hydrogen Bond Acceptor Count: 4
- Heavy Atom Count: 19
- Rotatable Bond Count: 6
- Complexity: 316
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 1
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Surface Charge: -1
- XLogP3: 2.2
- Topological Polar Surface Area: 75.6
Experimental Properties
- Color/Form: White powder
- Density: 1.1356 (rough estimate)
- Melting Point: 85-88 oC
- Boiling Point: 426.6°C at 760 mmHg
- Flash Point: 211.8℃
- Refractive Index: -25 ° (C=1, EtOH)
- Water Partition Coefficient: Insoluble
- PSA: 75.63000
- LogP: 2.59790
- Specific Rotation: -26 o (c=2,ethanol)
- Optical Activity: [α]20/D ?25±1°, c =?1% in ethanol
- Solubility: Insoluble in water
- Vapor Pressure: 0.0±1.1 mmHg at 25°C
Boc-D-Phe-OH Security Information
- Signal Word：Warning
- Hazard Statement： H302-H315-H319-H332-H335
- Warning Statement： P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501
- Hazardous Material transportation number：NONH for all modes of transport
- WGK Germany：3
- Safety Instruction： S24/25
-
Hazardous Material Identification：
- Safety Term：S24/25
- Storage Condition：2-8°C
Boc-D-Phe-OH Customs Data
- HS CODE：2924299090
- Customs Data：
China Customs Code:
2924299090Overview:
2924299090. Other cyclic amides(Including cyclic carbamates)(Including their derivatives as well as their salts). VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:30.0%
Declaration elements:
Product Name, component content, use to, packing
Summary:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
Boc-D-Phe-OH Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Chemenu | CM100617-500g |
BOC-D-PHE-OH |
18942-49-9 | 97% | 500g |
$247 | 2021-06-09 | |
| Fluorochem | M03311-1g |
Boc-D-Phe-OH |
18942-49-9 | 98% | 1g |
￡10.00 | 2022-02-28 | |
| Fluorochem | M03311-5g |
Boc-D-Phe-OH |
18942-49-9 | 98% | 5g |
￡11.00 | 2022-02-28 | |
| Fluorochem | M03311-25g |
Boc-D-Phe-OH |
18942-49-9 | 98% | 25g |
￡14.00 | 2022-02-28 | |
| Fluorochem | M03311-100g |
Boc-D-Phe-OH |
18942-49-9 | 98% | 100g |
￡42.00 | 2022-02-28 | |
| NAN JING HUA XUE SHI JI GU FEN Co., Ltd. | C0687609351- 5g |
Boc-D-Phe-OH |
18942-49-9 | 99%（HPLC) | 5g |
￥ 54.1 | 2021-05-18 | |
| NAN JING HUA XUE SHI JI GU FEN Co., Ltd. | C0687609343- 25g |
Boc-D-Phe-OH |
18942-49-9 | 99%（HPLC) | 25g |
￥ 127.1 | 2021-05-18 | |
| NAN JING HUA XUE SHI JI GU FEN Co., Ltd. | C0687609335- 100g |
Boc-D-Phe-OH |
18942-49-9 | 99%（HPLC) | 100g |
￥ 494.1 | 2021-05-18 | |
| Apollo Scientific | OR350041-25g |
Boc-D-phenylalanine |
18942-49-9 | 25g |
￡29.00 | 2025-02-19 | ||
| Apollo Scientific | OR350041-100g |
Boc-D-phenylalanine |
18942-49-9 | 100g |
￡96.00 | 2025-02-19 |
Boc-D-Phe-OH Suppliers
Suzhou Senfeida Chemical Co., Ltd
Gold Member
Audited Supplier
(CAS:18942-49-9)BOC-D-Phenylalanine
Order Number:sfd1335
Stock Status:in Stock
Quantity:200kg
Purity:99.9%
Pricing Information Last Updated:Friday, 19 July 2024 14:32
Price ($):discuss personally
Email:[email protected]
Tiancheng Chemical (Jiangsu) Co., Ltd
Gold Member
Audited Supplier
(CAS:18942-49-9)Boc-D-苯丙氨酸
Order Number:LE25956684
Stock Status:in Stock
Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Friday, 20 June 2025 12:54
Price ($):discuss personally
Email:[email protected]
Boc-D-Phe-OH Related Literature
-
Haidi Li,Junyou Li,Jie Chao,Zixin Zhang,Chuanguang Qin Org. Chem. Front. 2022 9 946
-
Holger A. Scheidt,Annemarie Sickert,Thomas Meier,Nicola Castellucci,Claudia Tomasini,Daniel Huster Org. Biomol. Chem. 2011 9 6998
-
M. L. Di Gioia,A. Barattucci,P. Bonaccorsi,A. Leggio,L. Minuti,E. Romio,A. Temperini,C. Siciliano RSC Adv. 2014 4 2678
-
Luciano Ricci,Lorenzo Sernissi,Dina Scarpi,Francesca Bianchini,Alessandro Contini,Ernesto G. Occhiato Org. Biomol. Chem. 2017 15 6826
-
Ting Lian,Wei Liu,Yi Li,Yonggang Yang New J. Chem. 2023 47 653
18942-49-9 (Boc-D-Phe-OH) Related Products
- 62129-44-6(Boc-4-Iodo-L-phenylalanine)
- 41153-30-4((S)-2-((tert-Butoxycarbonyl)amino)-3-(4-fluorophenyl)propanoic acid)
- 57292-45-2((2R)-2-(tert-butoxycarbonylamino)-3-(4-fluorophenyl)propanoic acid)
- 37553-65-4(Boc-N-Me-Phe-OH)
- 13734-34-4((2S)-2-(tert-butoxycarbonylamino)-3-phenyl-propanoic acid)
- 53267-93-9(Boc-Tyr(Me)-OH)
- 55533-24-9((S)-3-(4-Aminophenyl)-2-((tert-butoxycarbonyl)amino)propanoic acid)
- 70642-86-3(Boc-D-Tyr-OH)
- 51987-73-6(N-Boc-L-phenylalanine methyl ester)
- 3978-80-1(N-Boc-L-tyrosine)
