Cas no 1892830-19-1 (2-Bromo-5-(ethoxymethyl)-1,3-oxazole)

2-Bromo-5-(ethoxymethyl)-1,3-oxazole is a brominated oxazole derivative featuring an ethoxymethyl substituent at the 5-position. This compound serves as a versatile intermediate in organic synthesis, particularly in the construction of heterocyclic frameworks and pharmaceutical scaffolds. The bromine atom at the 2-position enhances reactivity for cross-coupling reactions, such as Suzuki or Buchwald-Hartwig couplings, while the ethoxymethyl group offers potential for further functionalization. Its stable oxazole core contributes to its utility in medicinal chemistry and agrochemical research. The compound is typically handled under inert conditions due to its sensitivity to moisture and air. Suitable for research and industrial applications requiring precise heterocyclic modifications.
2-Bromo-5-(ethoxymethyl)-1,3-oxazole structure
1892830-19-1 structure
Product Name:2-Bromo-5-(ethoxymethyl)-1,3-oxazole
CAS No:1892830-19-1
MF:C6H8BrNO2
MW:206.037220954895
CID:6220846
PubChem ID:117192321
Update Time:2025-10-28

2-Bromo-5-(ethoxymethyl)-1,3-oxazole Chemical and Physical Properties

Names and Identifiers

    • 2-bromo-5-(ethoxymethyl)-1,3-oxazole
    • EN300-7294762
    • 1892830-19-1
    • 2-Bromo-5-(ethoxymethyl)-1,3-oxazole
    • Inchi: 1S/C6H8BrNO2/c1-2-9-4-5-3-8-6(7)10-5/h3H,2,4H2,1H3
    • InChI Key: ZWWUJTIRYKRLQS-UHFFFAOYSA-N
    • SMILES: BrC1=NC=C(COCC)O1

Computed Properties

  • Exact Mass: 204.97384g/mol
  • Monoisotopic Mass: 204.97384g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 10
  • Rotatable Bond Count: 3
  • Complexity: 102
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 1.4
  • Topological Polar Surface Area: 35.3?2

2-Bromo-5-(ethoxymethyl)-1,3-oxazole Pricemore >>

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Additional information on 2-Bromo-5-(ethoxymethyl)-1,3-oxazole

2-Bromo-5-(ethoxymethyl)-1,3-oxazole: A Comprehensive Overview

2-Bromo-5-(ethoxymethyl)-1,3-oxazole, also known by its CAS registry number CAS No. 1892830-19-1, is a heterocyclic compound with significant applications in organic synthesis and materials science. This compound belongs to the class of oxazoles, which are five-membered rings consisting of two double bonds and two oxygen atoms. The presence of a bromine atom at the 2-position and an ethoxymethyl group at the 5-position makes this compound unique and versatile in various chemical reactions.

The synthesis of 2-Bromo-5-(ethoxymethyl)-1,3-oxazole typically involves multi-step reactions, often starting from readily available starting materials. Recent advancements in catalytic methods have enabled more efficient and environmentally friendly syntheses. For instance, researchers have explored the use of transition metal catalysts to facilitate the formation of the oxazole ring under mild conditions. These methods not only improve yield but also reduce the environmental footprint compared to traditional approaches.

One of the most notable applications of 2-Bromo-5-(ethoxymethyl)-1,3-oxazole is in the field of organic electronics. The compound's ability to act as a building block for more complex structures has been leveraged in the development of advanced materials such as organic light-emitting diodes (OLEDs) and flexible electronics. Recent studies have demonstrated that incorporating this oxazole derivative into polymer frameworks can significantly enhance charge transport properties, making it a valuable component in next-generation electronic devices.

In addition to its role in materials science, 2-Bromo-5-(ethoxymethyl)-1,3-oxazole has also found applications in medicinal chemistry. The compound serves as an intermediate in the synthesis of bioactive molecules, particularly those targeting specific biological pathways. For example, researchers have utilized this oxazole derivative to develop potential anti-cancer agents that exhibit selective cytotoxicity against cancer cells while sparing healthy cells. These findings highlight the compound's potential in drug discovery and development.

The structural versatility of 2-Bromo-5-(ethoxymethyl)-1,3-oxazole also makes it an attractive candidate for use in sensor technologies. Its ability to undergo reversible redox reactions under specific conditions has been exploited in the design of electrochemical sensors for detecting analytes such as glucose and heavy metals. Recent breakthroughs in nanotechnology have further enhanced the sensitivity and selectivity of these sensors, paving the way for their integration into point-of-care diagnostic devices.

In conclusion, 2-Bromo-5-(ethoxymethyl)-1,3-oxazole is a multifaceted compound with a wide range of applications across various scientific disciplines. Its unique chemical properties and structural flexibility continue to drive innovative research and development efforts. As advancements in synthetic methodologies and material science progress, this compound is poised to play an even more significant role in shaping future technologies and therapeutic solutions.

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