Cas no 185963-32-0 (3,5-Bis(aminomethyl)benzoic acid dihydrochloride)

3,5-Bis(aminomethyl)benzoic acid dihydrochloride is a bifunctional aromatic compound featuring two primary amine groups and a carboxylic acid moiety, making it a versatile building block in organic synthesis and pharmaceutical applications. The dihydrochloride form enhances solubility and stability, facilitating its use in peptide coupling reactions and as a precursor for heterocyclic compounds. Its rigid benzene core and symmetrical functionalization allow for precise molecular design in drug development and material science. The compound’s high purity and well-defined structure ensure reproducibility in research and industrial processes. Suitable for use in controlled reactions, it is particularly valuable in the synthesis of complex molecules requiring selective amine or carboxylate modifications.
3,5-Bis(aminomethyl)benzoic acid dihydrochloride structure
185963-32-0 structure
Product Name:3,5-Bis(aminomethyl)benzoic acid dihydrochloride
CAS No:185963-32-0
MF:C9H14Cl2N2O2
MW:253.125660419464
CID:2092976
PubChem ID:86280425
Update Time:2025-05-20

3,5-Bis(aminomethyl)benzoic acid dihydrochloride Chemical and Physical Properties

Names and Identifiers

    • 3,5-Bis(aminomethyl)benzoic acid dihydrochloride
    • 3,5-BIS(AMINOMETHYL)BENZOIC ACID 2HCL
    • SCHEMBL22400384
    • DS-8056
    • CS-0045347
    • I12017
    • 185963-32-0
    • 3,5-Bis(aminomethyl)benzoic acid dihydrochloride
    • AKOS024465082
    • 3,5-bis(aminomethyl)benzoic acid;dihydrochloride
    • 3,5-Bis(aminomethyl)benzoicaciddihydrochloride
    • DB-151092
    • MFCD28144945
    • MDL: MFCD28144945
    • Inchi: InChI=1S/C9H12N2O2.2ClH/c10-4-6-1-7(5-11)3-8(2-6)9(12)13;;/h1-3H,4-5,10-11H2,(H,12,13);2*1H
    • InChI Key: BKJBHQXEYLPXTQ-UHFFFAOYSA-N
    • SMILES: C1=C(C=C(C=C1CN)C(=O)O)CN.Cl.Cl

Computed Properties

  • Exact Mass: 252.0432331g/mol
  • Monoisotopic Mass: 252.0432331g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 3
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 15
  • Rotatable Bond Count: 3
  • Complexity: 173
  • Covalently-Bonded Unit Count: 3
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 89.3?2

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Additional information on 3,5-Bis(aminomethyl)benzoic acid dihydrochloride

Comprehensive Overview of 3,5-Bis(aminomethyl)benzoic acid dihydrochloride (CAS No. 185963-32-0)

3,5-Bis(aminomethyl)benzoic acid dihydrochloride (CAS No. 185963-32-0) is a highly specialized organic compound widely utilized in pharmaceutical research, biochemical applications, and material science. This compound, characterized by its dihydrochloride salt form, offers enhanced solubility and stability, making it a preferred choice for researchers focusing on drug development and peptide synthesis. Its unique structure, featuring two aminomethyl groups attached to a benzoic acid backbone, enables versatile reactivity, particularly in cross-linking reactions and bioconjugation.

In recent years, the demand for 3,5-Bis(aminomethyl)benzoic acid dihydrochloride has surged due to its pivotal role in targeted drug delivery systems and nanotechnology. Researchers are increasingly exploring its potential in cancer therapeutics, where its ability to form stable conjugates with biomolecules is highly valued. Additionally, its application in proteomics and enzyme immobilization has garnered significant attention, aligning with the growing interest in precision medicine and biocatalysis.

The synthesis of 3,5-Bis(aminomethyl)benzoic acid dihydrochloride involves a multi-step process, ensuring high purity and consistency. Its CAS No. 185963-32-0 serves as a critical identifier in regulatory and commercial databases, facilitating seamless procurement for laboratories worldwide. The compound’s physicochemical properties, including its melting point, solubility profile, and spectral data, are well-documented, supporting its integration into high-throughput screening and combinatorial chemistry workflows.

From an industrial perspective, 3,5-Bis(aminomethyl)benzoic acid dihydrochloride is a key intermediate in the production of advanced polymers and specialty coatings. Its bifunctional nature allows for the creation of cross-linked networks, enhancing the mechanical and thermal properties of materials. This aligns with the rising demand for sustainable materials and green chemistry initiatives, where efficiency and environmental impact are paramount.

For researchers seeking alternatives or derivatives, 3,5-Bis(aminomethyl)benzoic acid (without the dihydrochloride salt) is often compared, though the latter’s superior handling and reactivity make it more desirable for aqueous-phase reactions. Common queries in search engines include "3,5-Bis(aminomethyl)benzoic acid dihydrochloride solubility" and "CAS 185963-32-0 suppliers," reflecting practical concerns in laboratory settings. Addressing these, the compound’s MSDS and technical data sheets are readily available from reputable suppliers, ensuring compliance with safety protocols.

In summary, 3,5-Bis(aminomethyl)benzoic acid dihydrochloride (CAS No. 185963-32-0) stands as a cornerstone in modern scientific endeavors, bridging gaps between organic chemistry, biomedical engineering, and industrial applications. Its adaptability and well-characterized properties position it as a critical tool for innovation in an era dominated by personalized medicine and smart materials.

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