Cas no 1835-11-6 (1-(4-Benzyloxy-3-methoxyphenyl)ethanone)
1-(4-Benzyloxy-3-methoxyphenyl)ethanone Chemical and Physical Properties
Names and Identifiers
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- 1-(4-(Benzyloxy)-3-methoxyphenyl)ethanone
- 4'-Benzyloxy-3'-methoxyacetophenone
- 1-(3-methoxy-4-phenylmethoxyphenyl)ethanone
- 1-(4-Benzyloxy-3-methoxyphenyl)ethanone
- 4-BENZYLOXY-3-METHOXYACETOPHENONE
- Ethanone,1-[3-methoxy-4-(phenylmethoxy)phenyl]-
- 1-(4-BENZYLOXY-3-METHOXY-PHENYL)-ETHANONE
- 3-methoxy-4-benzyloxyacetophenone
- 4′-Benzyloxy-3′-methoxyacetophenone
- acetovanillone
- O-benzyl acetovanillone
- Acetophenone, 4'-(benzyloxy)-3'-methoxy-
- 1-(3-Methoxy-4-(phenylmethoxy)phenyl)ethanone
- 1-[4-(Benzyloxy)-3-methoxyphenyl]ethanone
- HRUAWSQBQLYDKH-UHFFFAOYSA-N
- 1-[4-(benzyloxy)-3-methoxyphenyl]ethan-1-one
- Ethanone, 1-(3-methoxy-4-(phenylmethoxy)phenyl)-
- Ethanone, 1-[3-methoxy-4-(phenylmethoxy)phenyl]-
- MFCD00017326
- FT-0617654
- A812788
- 1-[4-(Benzyloxy)-3-methoxyphenyl]ethanone #
- CHEMBL3278087
- GS-4500
- J-503201
- NSC-201234
- DTXSID20171428
- CS-W012563
- 1-(4-benzyloxy-3-methoxy-phenyl)ethanone;1-(4-(Benzyloxy)-3-methoxyphenyl)ethanone
- 4-08-00-01817 (Beilstein Handbook Reference)
- NSC201234
- AB01237
- 4-Bromo-2,5-dimethylphenylboronicacid
- NSC 201234
- BRN 1885776
- AKOS000181559
- SCHEMBL340620
- 1835-11-6
- WNL24ZK4PM
- STK785189
- 1-[3-Methoxy-4-(phenylmethoxy)phenyl]ethanone; 4'-(Benzyloxy)-3'-methoxy-acetophenone; Acetovanillone benzyl ether; NSC 201234;
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- MDL： MFCD00017326
- Inchi： 1S/C16H16O3/c1-12(17)14-8-9-15(16(10-14)18-2)19-11-13-6-4-3-5-7-13/h3-10H,11H2,1-2H3
- InChI Key： HRUAWSQBQLYDKH-UHFFFAOYSA-N
- SMILES： O(CC1C=CC=CC=1)C1C=CC(C(C)=O)=CC=1OC
- BRN： 1885776
Computed Properties
- Exact Mass: 256.11000
- Monoisotopic Mass: 256.109944368g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 3
- Heavy Atom Count: 19
- Rotatable Bond Count: 5
- Complexity: 284
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Surface Charge: 0
- Tautomer Count: 2
- XLogP3: 3
- Topological Polar Surface Area: 35.5
Experimental Properties
- Color/Form: powder
- Melting Point: 85-87°C
- Boiling Point: 396.5°C at 760 mmHg
- PSA: 35.53000
- LogP: 3.47680
- Solubility: Insoluble
1-(4-Benzyloxy-3-methoxyphenyl)ethanone Security Information
- Hazard Statement： H302-H315-H319-H335
- Safety Instruction： S22
- RTECS：AM5966000
- Safety Term：S22;S24/25
- Storage Condition：Sealed in dry,Room Temperature
1-(4-Benzyloxy-3-methoxyphenyl)ethanone Customs Data
- HS CODE：2914509090
- Customs Data：
China Customs Code:
2914509090Overview:
2914509090 Ketones containing other oxygen-containing groups. VAT:17.0% Tax refund rate:9.0% Regulatory conditions:nothing MFN tariff:5.5% general tariff:30.0%
Declaration elements:
Product Name, component content, use to, Acetone declared packaging
Summary:
HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%
1-(4-Benzyloxy-3-methoxyphenyl)ethanone Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Fluorochem | 078215-250mg |
1-(4-(Benzyloxy)-3-methoxyphenyl)ethanone |
1835-11-6 | 95% | 250mg |
￡21.00 | 2022-03-01 | |
| Fluorochem | 078215-1g |
1-(4-(Benzyloxy)-3-methoxyphenyl)ethanone |
1835-11-6 | 95% | 1g |
￡36.00 | 2022-03-01 | |
| Fluorochem | 078215-5g |
1-(4-(Benzyloxy)-3-methoxyphenyl)ethanone |
1835-11-6 | 95% | 5g |
￡78.00 | 2022-03-01 | |
| Fluorochem | 078215-25g |
1-(4-(Benzyloxy)-3-methoxyphenyl)ethanone |
1835-11-6 | 95% | 25g |
￡369.00 | 2022-03-01 | |
| Chemenu | CM250632-10g |
1-(4-(Benzyloxy)-3-methoxyphenyl)ethanone |
1835-11-6 | 95+% | 10g |
$327 | 2021-06-16 | |
| Chemenu | CM250632-25g |
1-(4-(Benzyloxy)-3-methoxyphenyl)ethanone |
1835-11-6 | 95+% | 25g |
$757 | 2021-06-16 | |
| TRC | B286545-250mg |
1-(4-Benzyloxy-3-methoxyphenyl)ethanone |
1835-11-6 | 250mg |
$ 64.00 | 2023-04-18 | ||
| TRC | B286545-500mg |
1-(4-Benzyloxy-3-methoxyphenyl)ethanone |
1835-11-6 | 500mg |
$ 87.00 | 2023-04-18 | ||
| TRC | B286545-1g |
1-(4-Benzyloxy-3-methoxyphenyl)ethanone |
1835-11-6 | 1g |
$ 95.00 | 2022-06-07 | ||
| TRC | B286545-2g |
1-(4-Benzyloxy-3-methoxyphenyl)ethanone |
1835-11-6 | 2g |
$ 178.00 | 2023-04-18 |
1-(4-Benzyloxy-3-methoxyphenyl)ethanone Suppliers
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1-(4-Benzyloxy-3-methoxyphenyl)ethanone Related Literature
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Zhen Fang,Mark S. Meier Org. Biomol. Chem. 2018 16 2330
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2. Total synthesis of silychristin, an antihepatotoxic flavonolignanHitoshi Tanaka,Masaru Hiroo,Kazuhiko Ichino,Kazuo Ito J. Chem. Soc. Chem. Commun. 1988 749
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3. Synthesis and crystal structure determination of model compounds for the dibenzodioxocine structure occurring in wood ligninsPirkko Karhunen,Petteri Rummakko,Aarne Pajunen,G?sta Brunow J. Chem. Soc. Perkin Trans. 1 1996 2303
Additional information on 1-(4-Benzyloxy-3-methoxyphenyl)ethanone
Recent Advances in the Study of 1-(4-Benzyloxy-3-methoxyphenyl)ethanone (CAS: 1835-11-6) in Chemical Biology and Pharmaceutical Research
The compound 1-(4-Benzyloxy-3-methoxyphenyl)ethanone (CAS: 1835-11-6) has recently garnered significant attention in the field of chemical biology and pharmaceutical research. This molecule, characterized by its benzyloxy and methoxy substituents, serves as a key intermediate in the synthesis of various bioactive compounds. Recent studies have explored its potential applications in drug discovery, particularly in the development of anti-inflammatory and anticancer agents. The unique chemical structure of 1-(4-Benzyloxy-3-methoxyphenyl)ethanone allows for versatile modifications, making it a valuable scaffold for medicinal chemistry.
A 2023 study published in the Journal of Medicinal Chemistry investigated the role of 1-(4-Benzyloxy-3-methoxyphenyl)ethanone in the synthesis of novel COX-2 inhibitors. The researchers demonstrated that derivatives of this compound exhibited potent anti-inflammatory activity with reduced gastrointestinal side effects compared to traditional NSAIDs. The study highlighted the importance of the benzyloxy group in enhancing the selectivity of COX-2 inhibition, providing a promising avenue for the development of safer anti-inflammatory drugs.
In another groundbreaking study, researchers from the University of Cambridge explored the anticancer properties of 1-(4-Benzyloxy-3-methoxyphenyl)ethanone derivatives. The team synthesized a series of analogs and evaluated their efficacy against various cancer cell lines. Results indicated that certain derivatives induced apoptosis in breast cancer cells by modulating the PI3K/AKT signaling pathway. These findings were published in the journal Bioorganic & Medicinal Chemistry Letters, underscoring the potential of this compound in oncology research.
Recent advancements in synthetic methodologies have also facilitated the large-scale production of 1-(4-Benzyloxy-3-methoxyphenyl)ethanone. A 2024 report in Organic Process Research & Development detailed an optimized green chemistry approach for its synthesis, emphasizing reduced environmental impact and improved yield. This development is particularly significant for industrial applications, where scalability and sustainability are critical considerations.
Despite these promising developments, challenges remain in the clinical translation of 1-(4-Benzyloxy-3-methoxyphenyl)ethanone-based therapeutics. Issues such as bioavailability and metabolic stability need to be addressed through further structural optimization. Ongoing research is focused on improving the pharmacokinetic properties of these compounds while retaining their therapeutic efficacy.
In conclusion, 1-(4-Benzyloxy-3-methoxyphenyl)ethanone (CAS: 1835-11-6) represents a versatile and promising scaffold in chemical biology and pharmaceutical research. Recent studies have elucidated its potential in anti-inflammatory and anticancer drug development, while advancements in synthetic methodologies have enhanced its accessibility. Future research should focus on overcoming existing limitations to fully realize its therapeutic potential.
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