• 1. Acetophenone derivatives: novel and potent small molecule inhibitors of monoamine oxidase B
  Zhi-Min Wang,Xue-Mei Li,Wei Xu,Fan Li,Jin Wang,Ling-Yi Kong,Xiao-Bing Wang Med. Chem. Commun. 2015 6 2146
• 2. Formal synthesis of the antitumour antibiotic CC-1065
  Richard E. Bolton,Christopher J. Moody,Martin Pass,Charles W. Rees,Gabriel Tojo J. Chem. Soc. Perkin Trans. 1 1988 2491
• 3. Synthesis of 6-hydroxy-1,4-dimethylisoquinoline and of ethyl 7-hydroxy-6-methoxy-1-methylisoquinoline-3-carboxylate
  Silvio J. Martinet,Lesley Larsen,Jonathan D. Street,John A. Joule J. Chem. Soc. Perkin Trans. 1 1988 1705

• Solvents and Organic Chemicals Organic Compounds Organic oxygen compounds Organooxygen compounds Ketones
• Solvents and Organic Chemicals Organic Compounds Organic oxygen compounds Organooxygen compounds Carbonyl compounds Ketones

Comprehensive Overview of 3-Benzyloxyacetophenone (CAS No. 34068-01-4): Properties, Applications, and Industry Insights

3-Benzyloxyacetophenone (CAS No. 34068-01-4) is an organic compound widely recognized for its versatile applications in pharmaceuticals, fragrances, and specialty chemical synthesis. This aromatic ketone, characterized by its benzyloxy and acetophenone functional groups, has garnered significant attention in research and industrial sectors due to its unique chemical properties and reactivity. Below, we delve into its molecular structure, synthesis methods, and emerging trends aligned with current market demands.

The molecular formula of 3-Benzyloxyacetophenone is C₁₅H₁₄O₂, with a molecular weight of 226.27 g/mol. Its structure features a benzyl ether linkage at the meta-position of the acetophenone ring, which enhances its solubility in organic solvents like ethanol and dichloromethane. This property makes it a valuable intermediate in organic synthesis, particularly for constructing complex molecules such as flavonoids and chiral auxiliaries.

Recent advancements in green chemistry have spurred interest in eco-friendly synthesis routes for 3-Benzyloxyacetophenone. Researchers are exploring catalytic methods using biodegradable reagents or microwave-assisted reactions to reduce waste and energy consumption—a response to the growing demand for sustainable chemical processes. These innovations align with global initiatives like the UN Sustainable Development Goals (SDGs), particularly Goal 12 (Responsible Consumption and Production).

In the pharmaceutical industry, 3-Benzyloxyacetophenone serves as a precursor for drug discovery and medicinal chemistry. Its derivatives are investigated for potential bioactivities, including anti-inflammatory and antioxidant effects. A 2023 study highlighted its role in synthesizing tyrosinase inhibitors, which are relevant for treating hyperpigmentation disorders—a hot topic in cosmeceutical research.

The fragrance industry also leverages 3-Benzyloxyacetophenone due to its mild, sweet odor profile. It is incorporated into fine perfumery and flavor enhancers, often as a fixative agent to prolong scent longevity. With consumers increasingly favoring natural-inspired aromas, this compound’s synthetic flexibility allows perfumers to mimic rare botanical extracts sustainably.

From an SEO perspective, common user queries include "3-Benzyloxyacetophenone solubility," "CAS 34068-01-4 suppliers," and "benzyloxyacetophenone synthesis mechanism." Addressing these, we note that the compound’s solubility data is well-documented in Hansen solubility parameters databases, while its commercial availability spans global specialty chemical distributors. Analytical techniques like HPLC and GC-MS are recommended for purity verification.

Regulatory compliance is another critical focus. 3-Benzyloxyacetophenone is not classified under restricted lists like REACH Annex XVII or TSCA, but users should adhere to Good Laboratory Practices (GLP) when handling it. Safety Data Sheets (SDS) recommend using personal protective equipment (PPE) such as nitrile gloves and goggles to prevent irritation.

Future prospects for 3-Benzyloxyacetophenone include its integration into advanced material science, such as organic semiconductors or photoinitiators for UV-curable resins. As industries pivot toward bio-based alternatives, this compound’s adaptability positions it as a candidate for circular economy innovations.

In summary, 3-Benzyloxyacetophenone (CAS No. 34068-01-4) exemplifies the intersection of traditional chemistry and modern sustainability. Its multifaceted applications—from pharmaceutical intermediates to fragrance components—underscore its enduring relevance. By addressing user queries and aligning with trends like green synthesis and cosmeceuticals, this overview aims to bridge technical depth with accessible insights for researchers and industry stakeholders alike.

• 28924-21-2(3’,5’-Dibenzyloxyacetophenone)
• 4495-66-3(4-Benzyloxypropiophenone)
• 69736-33-0(2-(3-(Benzyloxy)phenyl)-2-oxoacetaldehyde hydrate)
• 54696-05-8(4-Benzyloxyacetophenone)
• 52600-91-6(1-(3-ethoxyphenyl)ethan-1-one)
• 37951-47-6(3'-Benzyloxy Propiophenone)
• 54589-41-2(4-Benzyloxybenzophenone)
• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
• 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)