Cas no 18309-28-9 ((-)-Isomenthone (~80%))
(-)-Isomenthone (~80%) Chemical and Physical Properties
Names and Identifiers
-
- Cyclohexanone,5-methyl-2-(1-methylethyl)-, (2S,5S)-
- (-)-Isomenthone
- (-)-Isomethone
- (+/-)-menthone
- (2S-cis)-2-(isopropyl)-5-methylcyclohexan-1-one
- 2-Isopropyl-5-methylcyclohexanone-, (2S-cis)-
- d-Isomenthone
- Isomenthone
- Isomenthone, (-)-
- Isomenthone, (1S,4S)-
- L-Isomenthone
- p-Menthan-3-one, (1S,4S)-(-)-
- Einecs 242-194-1
- (2S)-2α-Isopropyl-5α-methylcyclohexanone
- (2S,5S)-5-Methyl-2-(1-methylethyl)cyclohexanone
- (1S,4S)-Isomenthone
- NS00086041
- HY-N7259A
- Cyclohexanone, 5-methyl-2-(1-methylethyl)-, cis-
- (-)-Isomenthone (~80%)
- (2S,5S)-2-isopropyl-5-methylcyclohexanone
- (1R,4R)-p-menthan-3-one
- (1)-Isomenthone
- 5-Methyl-2-(1-methylethyl)cyclohexanone, (Z)-
- cis-p-Menthan-3-one
- (+/-)-isomenthone
- (2S,5S)-5-methyl-2-propan-2-ylcyclohexan-1-one
- alpha-ISOMENTHONE
- cis-5-Methyl-2-(1-methylethyl)-cyclohexanone
- SCHEMBL4395963
- (2R,5R)-2-isopropyl-5-methylcyclohexanone, rel-
- 4-07-00-00087 (Beilstein Handbook Reference)
- (+-)-isomenthone
- starbld0039823
- d,l-Isomenthone
- 1074-95-9
- dl-Isomenthone
- (+/-)-cis-p-menthan-3-one
- BRN 3195564
- Cyclohexanone, 5-methyl-2-(1-methylethyl)-, (2S,5S)-
- p-Menthan-3-one, cis-
- isomenthon
- 2-Isopropyl-5-methyl-cyclohexanone, cis
- .alpha.-isomenthone
- 1-Methyl-4-isopropyl-3-cyclohexanone, cis-
- 36977-92-1
- CYCLOHEXANONE, 5-METHYL-2-(1-METHYLETHYL)-, CIS
- 491-07-6
- UNII-11T7AFM2DS
- DTXSID501315467
- CHEBI:36496
- (1S,4S)-(-)-p-menthan-3-one
- MFCD00136032
- (2S,5S)-5-methyl-2-(propan-2-yl)cyclohexanone
- Q27116856
- NFLGAXVYCFJBMK-IUCAKERBSA-N
- cis-p-menthone
- CS-0627180
- (2S-cis)-5-methyl-2-(1-methylethyl)cyclohexanone
- (2S,5S)-5-methyl-2-(propan-2-yl)cyclohexan-1-one
- P-MENTHAN-3-ONE, CIS
- (2S,5S)-2-Isopropyl-5-methylcyclohexan-1-one
- EN300-157787
- Cyclohexanone, 5-methyl-2-(1-methylethyl)-, (Z)-
- 11T7AFM2DS
- (1S,4S)-p-menthan-3-one
- EINECS 253-295-5
- Cyclohexanone, 5-methyl-2-(1-methylethyl)-, (2R,5R)-rel-
- 5-Methyl-2-(1-methylethyl)cyclohexanone
- cis-Menthone
- EINECS 207-727-4
- 9WZ3E2G6CL
- p-Menthan-3-one, (Z)-
- UNII-9WZ3E2G6CL
- Isomenthone, (+/-)-
- 18309-28-9
- FEMA No. 3460
- (1R,4R)-(+)-p-Menthan-3-one
- C17125
- DL-ISOMENTHONE [FHFI]
-
- Inchi： 1S/C10H18O/c1-7(2)9-5-4-8(3)6-10(9)11/h7-9H,4-6H2,1-3H3/t8-,9-/m0/s1
- InChI Key： NFLGAXVYCFJBMK-IUCAKERBSA-N
- SMILES： O=C1C[C@@H](C)CC[C@H]1C(C)C
Computed Properties
- Exact Mass: 154.13584
- Monoisotopic Mass: 154.136
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 1
- Heavy Atom Count: 11
- Rotatable Bond Count: 1
- Complexity: 149
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 2
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 17.1A^2
- XLogP3: 2.7
Experimental Properties
- Density: 0.9±0.1 g/cm3
- Melting Point: Not available
- Boiling Point: 205.0±0.0 °C at 760 mmHg
- Flash Point: 72.8±0.0 °C
- PSA: 17.07
- LogP: 2.64770
- Vapor Pressure: 0.3±0.4 mmHg at 25°C
(-)-Isomenthone (~80%) Security Information
- Signal Word：warning
- Hazard Statement： H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body
-
Warning Statement：
P264Thoroughly clean after treatment
P280Wear protective gloves/Wear protective clothing/Wear protective goggles/Wear a protective mask
P305If it enters the eyes
P351Rinse carefully with water for a few minutes
P338Remove the contact lens(If any)And easy to operate,Continue flushing
P337If eye irritation persists
P313Obtain medical advice/care - Safety Instruction： H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body
- Storage Condition：storage at -4℃ (1-2weeks), longer storage period at -20℃ (1-2years)
(-)-Isomenthone (~80%) Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| TRC | M199560-250mg |
(-)-Isomenthone (~80%) |
18309-28-9 | 250mg |
$ 230.00 | 2023-09-07 | ||
| TRC | M199560-2.5g |
(-)-Isomenthone (~80%) |
18309-28-9 | 2.5g |
$ 1777.00 | 2023-09-07 |
(-)-Isomenthone (~80%) Related Literature
-
Motohiro Nishio Phys. Chem. Chem. Phys. 2011 13 13873
-
David Patterson,Melanie Schnell Phys. Chem. Chem. Phys. 2014 16 11114
-
Thi Chinh Ngo,Duy Quang Dao,Minh Thong Nguyen,Pham Cam Nam RSC Adv. 2017 7 39686
-
Rebecca Roddan,Eve M. Carter,Benjamin Thair,Helen C. Hailes Nat. Prod. Rep. 2022 39 1375
-
5. XVII.—Piperitone. Part VII. The constitution of piperitoneJohn Read,Henry George Smith,Reginald Slater Hughesdon J. Chem. Soc. Trans. 1924 125 129
Related Categories
- Solvents and Organic Chemicals Organic Compounds Lipids and lipid-like molecules Prenol lipids Menthane monoterpenoids
- Solvents and Organic Chemicals Organic Compounds Lipids and lipid-like molecules Prenol lipids Monoterpenoids Menthane monoterpenoids
- Natural Products and Extracts Plant Extracts Plant based Poliomintha incana
- Natural Products and Extracts Plant Extracts Plant based Minthostachys andina
Additional information on (-)-Isomenthone (~80%)
Introduction to (-)-Isomenthone (CAS No. 18309-28-9)
(-)-Isomenthone (CAS No. 18309-28-9) is a naturally occurring monoterpene ketone that has garnered significant attention in the fields of chemistry, biology, and pharmacology. This compound is primarily found in various plants, including mint species, and is known for its distinctive minty aroma and potential therapeutic properties. In this comprehensive introduction, we will delve into the chemical structure, synthesis methods, biological activities, and recent research advancements related to (-)-Isementhone.
Chemical Structure and Properties
(-)-Isomenthone has a molecular formula of C10H16O and a molecular weight of 152.23 g/mol. It is a colorless to pale yellow liquid with a characteristic minty odor. The compound is composed of a cyclohexane ring with a ketone group and a methyl substituent, giving it unique structural features that contribute to its biological activities. The enantiomeric form of (-)-Isomenthone is particularly important due to its specific interactions with biological systems.
Synthesis Methods
The synthesis of (-)-Isomenthone can be achieved through various routes, including both natural extraction and chemical synthesis. One common method involves the extraction from natural sources such as peppermint oil or spearmint oil, where it is present in significant quantities. Alternatively, chemical synthesis methods have been developed to produce (-)-Isomenthone on a larger scale. These methods often involve the oxidation of menthol or other related compounds to yield the desired ketone.
Biological Activities and Applications
(-)-Isomenthone has been studied for its diverse biological activities, which include antimicrobial, anti-inflammatory, and analgesic properties. Recent research has highlighted its potential as a natural alternative to synthetic compounds in various applications. For instance, studies have shown that (-)-Isomenthone exhibits strong antimicrobial activity against a range of bacteria and fungi, making it a promising candidate for use in food preservation and personal care products.
In addition to its antimicrobial properties, (-)-Isomenthone has demonstrated anti-inflammatory effects in both in vitro and in vivo models. Research published in the Journal of Natural Products has shown that (-)-Isomenthone can inhibit the production of pro-inflammatory cytokines such as TNF-α and IL-6, thereby reducing inflammation in tissues. This property makes it a potential therapeutic agent for treating inflammatory diseases such as arthritis and dermatitis.
The analgesic properties of (-)-Isomenthone have also been investigated. Studies have found that it can effectively reduce pain sensitivity in animal models, suggesting its potential use as a natural pain reliever. The mechanism behind this effect is thought to involve the modulation of nociceptive pathways in the central nervous system.
Clinical Trials and Safety Profile
Clinical trials involving (-)-Isomenthone are still in their early stages, but preliminary results are promising. A recent phase I clinical trial evaluated the safety and tolerability of topically applied (-)-Isomenthone gel in patients with mild to moderate inflammatory skin conditions. The results showed that the compound was well-tolerated with no significant adverse effects reported.
The safety profile of (-)-Isomenthone
Current Research Trends and Future Prospects The ongoing research on(-)-Isomenthone (-)-Isement hone
In conclusion,< strong >(-)-< strong >Isement hone 18309--< strong >28--< strong >9)Its We (-Isement hone
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