Cas no 182410-00-0 (Betadex Sulfobutyl Ether Sodium)

Betadex Sulfobutyl Ether Sodium (SBECD) is a sulfobutyl ether derivative of β-cyclodextrin, widely used as a solubilizing and stabilizing agent in pharmaceutical formulations. Its key advantages include enhanced water solubility compared to native cyclodextrins, making it particularly effective for improving the bioavailability of poorly soluble drugs. SBECD forms non-covalent inclusion complexes with hydrophobic molecules, thereby increasing their dissolution and stability. It is biocompatible and exhibits low toxicity, making it suitable for parenteral and oral drug delivery systems. Additionally, its anionic sulfobutyl groups contribute to reduced renal toxicity, further broadening its applicability in injectable formulations. SBECD is commonly employed in preclinical and clinical drug development.
Betadex Sulfobutyl Ether Sodium structure
182410-00-0 structure
Product Name:Betadex Sulfobutyl Ether Sodium
CAS No:182410-00-0
MF:C42H70O35
MW:1134.98421812057
MDL:MFCD12032209
CID:200565
Update Time:2026-01-28

Betadex Sulfobutyl Ether Sodium Chemical and Physical Properties

Names and Identifiers

    • Betadex Sulfobutyl Ether Sodium
    • beta.-Cyclodextrin, sulfobutyl ethers, sodium salts
    • CAPTISOL
    • Sodium sulfobutylether β-cyclodextrin
    • Betadex Sulfobutyl Ether Sodium (500 mg)
    • sulfobutyl ether B-cyclodextrin
    • sodiuM salts
    • sulfobutyl ethers
    • SodiuM Sulphobutylether-β-Cyclodextrin
    • β-Cyclodextrin Sulfobutyl Ethers, Sodium Salts
    • b-Cyclodextrin, sulfobutyl ethers,sodium salts
    • BetadexSulfobutylE
    • SODIUM SULPHOBUTYLETHER-BETA-CYCLODEXTRIN
    • Sulfobutylether-β-Cyclodextrin
    • CS-0731
    • SBE-Beta-CD
    • beta-Cyclodextrin sulfobutyl ethers sodium salts
    • SBEBCD
    • SBE-β-CD
    • SBE-(beta)-CD
    • Sulfobutyl -β- cyclodextrin sodium
    • β-Cyclodextrin, sulfobutyl ethers, sodium salts
    • DOCOSAHEXAENOICACID
    • Sulfobutyl beta cyclodextrin ether sodium
    • beta-Cyclodextrinsulfobutyl ethers sodium salts,99%
    • .beta.-Cyclodextrin, sulfobutyl ethers, sodium salts
    • SBE-β-CD(Sulfobutyl Ether-β-cyclodextrin Sodium salt)
    • BETADEX SULFOBUTYL ETHER SOIDUM
    • sulfobutyl ether sodium salt
    • betadex sulfobuytl ether sodium
    • β-Cyclodextrin, sulfobutyl ethers
    • Sulfobutylated beta-cyclodextrin sodium salt (DS~4)
    • Sulfobutylated beta-cyclodextrin sodium salt (DS~6)
    • MDL: MFCD12032209
    • Inchi: 1S/C42H70O35/c43-1-8-29-15(50)22(57)36(64-8)72-30-9(2-44)66-38(24(59)17(30)52)74-32-11(4-46)68-40(26(61)19(32)54)76-34-13(6-48)70-42(28(63)21(34)56)77-35-14(7-49)69-41(27(62)20(35)55)75-33-12(5-47)67-39(25(60)18(33)53)73-31-10(3-45)65-37(71-29)23(58)16(31)51/h8-63H,1-7H2/t8?,9?,10?,11?,12?,13?,14?,15?,16?,17?,18?,19?,20?,21?,22?,23?,24?,25?,26?,27?,28?,29-,30-,31-,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,42+/m1/s1
    • InChI Key: WHGYBXFWUBPSRW-PVYQGTNRSA-N
    • SMILES: [C@H]12C(O)C(O)[C@H](O[C@@H]3OC(CO)[C@H](C(O)C3O)O[C@H]3OC(CO)[C@H](C(O)C3O)O[C@H]3OC(CO)[C@H](C(O)C3O)O[C@H]3OC(CO)[C@H](C(O)C3O)O[C@H]3OC(CO)[C@H](C(O)C3O)O[C@H]3OC(CO)[C@H](C(O)C3O)O1)C(CO)O2

Computed Properties

  • Exact Mass: 1450.37000
  • Monoisotopic Mass: 411.150429
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 14
  • Hydrogen Bond Acceptor Count: 56
  • Heavy Atom Count: 140
  • Rotatable Bond Count: 49
  • Complexity: 503
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 87.2

Experimental Properties

  • Color/Form: White powder
  • Melting Point: 266-274°C
  • Boiling Point: No data available
  • Flash Point: No data available
  • Solubility: Soluble in water. Insoluble in acetone, methanol, chloroform.
  • PSA: 663.21000
  • LogP: -12.36960
  • Specific Rotation: +80.0°~+91.0°
  • Vapor Pressure: No data available

Betadex Sulfobutyl Ether Sodium Security Information

Betadex Sulfobutyl Ether Sodium Customs Data

  • HS CODE:2940006000

Betadex Sulfobutyl Ether Sodium Pricemore >>

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Betadex Sulfobutyl Ether Sodium Suppliers

Suzhou Senfeida Chemical Co., Ltd
Gold Member
Audited Supplier Audited Supplier
(CAS:182410-00-0)Betadex Sulfobutyl Ether Sodium
Order Number:sfd8850
Stock Status:in Stock
Quantity:200kg
Purity:99.9%
Pricing Information Last Updated:Friday, 19 July 2024 14:35
Price ($):discuss personally
Shandong Zhonghuan Zhongjie Biotechnology Co.,Ltd
Gold Member
Audited Supplier Audited Supplier
(CAS:182410-00-0)Betadex sulfobutyl ether sodium
Order Number:C0006
Stock Status:in Stock
Quantity:1kg;2kg;10kg
Purity:99%
Pricing Information Last Updated:Friday, 9 January 2026 10:00
Price ($):inquiry

Betadex Sulfobutyl Ether Sodium Spectrogram

1H NMR 300 MHz DMSO
1H NMR
13C NMR
13C NMR

Additional information on Betadex Sulfobutyl Ether Sodium

Comprehensive Guide to Betadex Sulfobutyl Ether Sodium (CAS No. 182410-00-0): Properties, Applications, and Market Insights

Betadex Sulfobutyl Ether Sodium, also known as Sulfobutylether-β-Cyclodextrin Sodium (SBECD), is a chemically modified cyclodextrin derivative with the CAS number 182410-00-0. This compound has gained significant attention in the pharmaceutical and biotechnology industries due to its unique properties as a solubility enhancer and stabilizer. With the increasing demand for advanced drug delivery systems, SBECD has become a critical excipient in formulations for poorly water-soluble drugs.

The molecular structure of Betadex Sulfobutyl Ether Sodium consists of a β-cyclodextrin backbone substituted with sulfobutyl ether groups, which are negatively charged at physiological pH. This modification enhances its water solubility and reduces renal toxicity compared to native cyclodextrins. Researchers and formulators often search for "SBECD solubility enhancement" or "Betadex Sulfobutyl Ether Sodium in drug delivery" to understand its mechanisms of action, which include forming inclusion complexes with hydrophobic drug molecules.

One of the most prominent applications of Betadex Sulfobutyl Ether Sodium is in the formulation of injectable drugs. Its ability to improve the solubility of lipophilic compounds while maintaining low toxicity makes it ideal for parenteral formulations. Current trends show growing interest in "SBECD for mRNA vaccines" and "Betadex Sulfobutyl Ether Sodium in biopharmaceuticals," reflecting its potential in cutting-edge therapeutic areas. The compound's safety profile has been well-established through numerous studies, making it a preferred choice for regulatory-approved formulations.

The pharmaceutical industry is increasingly adopting Sulfobutylether-β-Cyclodextrin Sodium as a versatile excipient. Market analysis reveals rising searches for "SBECD manufacturers" and "Betadex Sulfobutyl Ether Sodium price," indicating growing commercial interest. The global market for cyclodextrin derivatives is projected to expand significantly, driven by the demand for advanced drug delivery solutions and biopharmaceutical formulations. Quality parameters such as "SBECD purity standards" and "Betadex Sulfobutyl Ether Sodium specifications" are critical considerations for pharmaceutical companies.

From a regulatory perspective, Betadex Sulfobutyl Ether Sodium has been approved by major health authorities worldwide for use in various drug products. Researchers frequently inquire about "SBECD regulatory status" and "Betadex Sulfobutyl Ether Sodium safety data," highlighting the importance of compliance in pharmaceutical applications. The compound's monograph is included in major pharmacopeias, ensuring standardized quality for global pharmaceutical use. Recent advancements in analytical methods for characterizing SBECD have further strengthened its position in the industry.

Beyond traditional pharmaceutical applications, Sulfobutylether-β-Cyclodextrin Sodium shows promise in emerging fields. There's growing interest in its potential for "SBECD in gene therapy" and "Betadex Sulfobutyl Ether Sodium for protein stabilization." These applications leverage the compound's ability to protect sensitive biological molecules from degradation while improving their delivery efficiency. The scientific community continues to explore novel uses of SBECD, particularly in advanced therapeutic medicinal products (ATMPs) and personalized medicine approaches.

Quality control of Betadex Sulfobutyl Ether Sodium remains a crucial aspect for manufacturers and end-users. Common search queries include "SBECD analytical methods" and "Betadex Sulfobutyl Ether Sodium testing protocols," reflecting the need for robust characterization techniques. Modern analytical approaches such as mass spectrometry and advanced chromatographic methods are employed to ensure batch-to-batch consistency and compliance with stringent pharmaceutical standards.

The environmental profile of Sulfobutylether-β-Cyclodextrin Sodium has also become a subject of interest, with searches for "SBECD biodegradability" and "Betadex Sulfobutyl Ether Sodium environmental impact" increasing. Studies indicate that SBECD exhibits favorable environmental characteristics compared to many synthetic excipients, aligning with the pharmaceutical industry's growing emphasis on green chemistry principles.

Looking ahead, the future of Betadex Sulfobutyl Ether Sodium appears promising as research continues to uncover new applications. The compound's versatility in addressing formulation challenges for new chemical entities and biologics positions it as a valuable tool in drug development. With ongoing innovations in drug delivery technologies and the expanding biopharmaceutical market, SBECD is poised to play an increasingly important role in modern therapeutics.

Recommended suppliers
Suzhou Senfeida Chemical Co., Ltd
(CAS:182410-00-0)Betadex Sulfobutyl Ether Sodium
sfd8850
Purity:99.9%
Quantity:200kg
Price ($):Inquiry
Email
Shandong Zhonghuan Zhongjie Biotechnology Co.,Ltd
(CAS:182410-00-0)Betadex sulfobutyl ether sodium
C0006
Purity:99%
Quantity:1kg;2kg;10kg
Price ($):Inquiry
Email