Cas no 181297-72-3 (2-(3-Chlorophenoxy)benzaldehyde)

2-(3-Chlorophenoxy)benzaldehyde is a chlorinated aromatic aldehyde with the molecular formula C??H?ClO?. It serves as a versatile intermediate in organic synthesis, particularly in the preparation of pharmaceuticals, agrochemicals, and specialty chemicals. The compound features a benzaldehyde core substituted with a 3-chlorophenoxy group, enhancing its reactivity in condensation and nucleophilic addition reactions. Its well-defined structure and high purity make it suitable for precise synthetic applications. The presence of both aldehyde and chloro-phenoxy functionalities allows for selective modifications, enabling the synthesis of complex derivatives. This compound is typically handled under controlled conditions due to its sensitivity to light and moisture.
2-(3-Chlorophenoxy)benzaldehyde structure
181297-72-3 structure
Product Name:2-(3-Chlorophenoxy)benzaldehyde
CAS No:181297-72-3
MF:C13H9ClO2
MW:232.66236281395
MDL:MFCD01568769
CID:1087637
PubChem ID:2763428
Update Time:2025-11-02

2-(3-Chlorophenoxy)benzaldehyde Chemical and Physical Properties

Names and Identifiers

    • 2-(3-Chlorophenoxy)benzaldehyde
    • 2-(3-CHLOROPHENOXY)BENZENECARBALDEHYDE
    • 2-(3'-chlorophenoxy)-benzaldehyde
    • 2-(m-chlorophenoxy)benzaldehyde
    • AC1MC8A3
    • AC1Q3IGS
    • AG-A-29659
    • CTK7I0028
    • SBB097993
    • CS-0324126
    • 181297-72-3
    • 2-(3-chloro-phenoxy)-benzaldehyde
    • MFCD01568769
    • AKOS000260505
    • DTXSID80376952
    • E76300
    • JEPWDAWNQGZIFB-UHFFFAOYSA-N
    • 12N-067
    • A1-32724
    • SCHEMBL5319954
    • DS-016222
    • MDL: MFCD01568769
    • Inchi: 1S/C13H9ClO2/c14-11-5-3-6-12(8-11)16-13-7-2-1-4-10(13)9-15/h1-9H
    • InChI Key: JEPWDAWNQGZIFB-UHFFFAOYSA-N
    • SMILES: ClC1=CC=CC(=C1)OC1C=CC=CC=1C=O

Computed Properties

  • Exact Mass: 232.0291072g/mol
  • Monoisotopic Mass: 232.0291072g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 16
  • Rotatable Bond Count: 3
  • Complexity: 232
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 3.5
  • Topological Polar Surface Area: 26.3?2

Experimental Properties

  • Melting Point: 35-37°C
  • Boiling Point: 130°C 0,05mm

2-(3-Chlorophenoxy)benzaldehyde Security Information

  • HazardClass:IRRITANT

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Additional information on 2-(3-Chlorophenoxy)benzaldehyde

2-(3-Chlorophenoxy)benzaldehyde (CAS 181297-72-3): A Versatile Chemical Intermediate for Modern Applications

2-(3-Chlorophenoxy)benzaldehyde (CAS 181297-72-3) is an important aromatic aldehyde compound that has gained significant attention in pharmaceutical and agrochemical research. This chlorinated benzaldehyde derivative serves as a crucial building block in organic synthesis, particularly in the development of novel bioactive molecules. Its unique molecular structure, featuring both phenoxy and aldehyde functional groups, makes it valuable for creating complex molecular architectures.

The growing interest in 2-(3-chlorophenoxy)benzaldehyde synthesis aligns with current trends in green chemistry and sustainable manufacturing. Researchers are actively exploring more efficient production methods that minimize environmental impact while maintaining high purity standards. Recent studies have focused on optimizing reaction conditions to improve yields of this benzaldehyde derivative, addressing one of the most common search queries in chemical databases.

In pharmaceutical applications, 2-(3-chlorophenoxy)benzaldehyde CAS 181297-72-3 serves as a precursor for various drug candidates. Its structural features make it particularly useful in developing central nervous system (CNS) active compounds and anti-inflammatory agents. The compound's ability to undergo diverse chemical transformations allows medicinal chemists to create libraries of potential drug molecules, answering the frequent question: "What are the uses of 3-chlorophenoxy benzaldehyde in drug discovery?"

The agrochemical industry has shown increasing demand for 2-(3-chlorophenoxy)benzaldehyde price and availability information, as this compound proves valuable in developing new crop protection agents. Its chlorophenoxy moiety contributes to the biological activity of several herbicide intermediates and plant growth regulators. Manufacturers are responding to market needs by scaling up production while maintaining strict quality control measures.

Analytical characterization of 2-(3-chlorophenoxy)benzaldehyde 181297-72-3 remains an important topic in chemical forums. Advanced techniques such as HPLC purity analysis, mass spectrometry, and NMR spectroscopy are routinely employed to verify the identity and quality of this compound. These analytical methods address common quality concerns raised by researchers searching for "how to test 3-chlorophenoxy benzaldehyde purity."

Storage and handling recommendations for 2-(3-chlorophenoxy)benzaldehyde CAS no 181297-72-3 frequently appear in safety discussions. While not classified as hazardous under normal conditions, proper storage in amber glass containers under inert atmosphere helps maintain stability. This information responds to the often-searched question about "best practices for storing chlorophenoxy benzaldehyde derivatives."

The global market for 2-(3-chlorophenoxy)benzaldehyde suppliers has expanded significantly in recent years, with growing demand from Asia-Pacific regions. Industry reports indicate increasing applications in electronic materials and specialty chemicals, beyond its traditional uses. This market trend aligns with searches for "emerging applications of chlorophenoxy aromatic aldehydes."

Recent patent literature reveals innovative applications of 2-(3-chlorophenoxy)benzaldehyde structure in material science. Researchers have utilized its molecular framework to develop liquid crystal compounds and organic semiconductors, addressing the growing interest in "benzaldehyde derivatives in advanced materials." These developments position the compound as valuable in electronics and display technologies.

Environmental fate studies of 2-(3-chlorophenoxy)benzaldehyde properties have gained attention due to increased regulatory focus. Research into its biodegradation pathways and ecotoxicological profile helps address sustainability concerns, responding to queries about "environmental impact of chlorophenoxy benzaldehydes." These studies support responsible use in industrial applications.

Academic interest in 2-(3-chlorophenoxy)benzaldehyde reactions continues to grow, with numerous publications exploring its nucleophilic addition and condensation reactions. The compound's reactivity makes it valuable for teaching advanced organic chemistry concepts, answering educational searches for "demonstration reactions using substituted benzaldehydes."

Quality specifications for 2-(3-chlorophenoxy)benzaldehyde technical data typically include parameters such as appearance, melting point, and purity levels. These specifications help buyers evaluate products when searching for "3-chlorophenoxy benzaldehyde quality standards." Reputable suppliers provide comprehensive analytical certificates to meet these information needs.

The future outlook for 2-(3-chlorophenoxy)benzaldehyde applications appears promising, with potential uses in flavor and fragrance intermediates and photoresist chemicals. These emerging applications respond to market demands for versatile chemical building blocks, as reflected in industry trend searches for "next-generation uses of aromatic aldehydes."

In conclusion, 2-(3-Chlorophenoxy)benzaldehyde (CAS 181297-72-3) represents a valuable chemical intermediate with diverse applications across multiple industries. Its importance in pharmaceutical research, agrochemical development, and advanced materials continues to drive scientific and commercial interest. As research progresses, new applications for this versatile benzaldehyde derivative are likely to emerge, solidifying its position in modern chemical synthesis.

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